Mira Jung
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View article: Proton-boron capture interaction enhances killing of radiation resistant cancer cells
Proton-boron capture interaction enhances killing of radiation resistant cancer cells Open
Background/objectives Studies involving the interaction of protons with boron ( 11 B) have shown potential for enhanced cell killing in cancer cells. However, theoretical analyses conducted using Monte Carlo simulations have not corroborat…
View article: Zero-Overhead Lexical Effect Handlers
Zero-Overhead Lexical Effect Handlers Open
Exception handlers—and effect handlers more generally—are language mechanisms for structured nonlocal control flow. A recent trend in language-design research has introduced lexically scoped handlers, which address a modularity problem wi…
View article: Spatial FAP Expression as Detected by 68 Ga-FAPI-46 Identifies Myofibroblasts Beyond the Infarct Scar After Reperfusion
Spatial FAP Expression as Detected by 68 Ga-FAPI-46 Identifies Myofibroblasts Beyond the Infarct Scar After Reperfusion Open
Purpose Myocardial infarction (MI) triggers complex cellular responses essential for tissue repair and remodeling, including myofibroblast activation. Fibroblast activation protein alpha (FAP) identifies activated myofibroblasts post-MI, h…
View article: Dual-targeting class I HDAC inhibitor and ATM activator, SP-1-303, preferentially inhibits estrogen receptor positive breast cancer cell growth
Dual-targeting class I HDAC inhibitor and ATM activator, SP-1-303, preferentially inhibits estrogen receptor positive breast cancer cell growth Open
Dual-targeting chromatin regulation and DNA damage repair signaling presents a promising avenue for cancer therapy. Applying rational drug design, we synthesized a potent dual-targeting small molecule, SP-1-303. Here, we report SP-1-303 as…
View article: Precision medicine targets for prostate cancers in African American men
Precision medicine targets for prostate cancers in African American men Open
To investigate molecular mechanisms underlying prostate cancer health disparities, the primary prostate epithelial cell cultures were established from the tumors and adjacent non-tumor tissues of prostatectomy specimens of African American…
View article: Supplementary Figure 5 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 5 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 5
View article: Supplementary Data Figure Legend from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Data Figure Legend from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Data Figure Legend
View article: Supplementary Figure 6 A_B from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 6 A_B from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 6 A_B
View article: Supplementary Figure 4 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 4 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 4
View article: Supplementary Data Figure Legend from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Data Figure Legend from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Data Figure Legend
View article: Supplementary Figure 1 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 1 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 1
View article: Supplementary Figure 2 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 2 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 2
View article: Supplementary Figure 3 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 3 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 3
View article: Supplementary Figure 1 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 1 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 1
View article: Supplementary Figure 4 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 4 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 4
View article: Supplementary Figure 6 C_D from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 6 C_D from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 6 C_D
View article: Data from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Data from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Radiotherapy is a curative cancer treatment modality that imparts damage to cellular DNA, induces immunogenic cell death, and activates antitumor immunity. Despite the radiotherapy-induced direct antitumor effect seen within the treated vo…
View article: Data from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Data from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Radiotherapy is a curative cancer treatment modality that imparts damage to cellular DNA, induces immunogenic cell death, and activates antitumor immunity. Despite the radiotherapy-induced direct antitumor effect seen within the treated vo…
View article: Supplementary Figure 3 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 3 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 3
View article: Supplementary Figure 6 A_B from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 6 A_B from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 6 A_B
View article: Supplementary Figure 5 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 5 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 5
View article: Supplementary Figure 2 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 2 from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 2
View article: Supplementary Figure 6 C_D from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Supplementary Figure 6 C_D from Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Supplementary Figure 6 C_D
View article: Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition
Radiotherapy-induced Immune Response Enhanced by Selective HDAC6 Inhibition Open
Radiotherapy is a curative cancer treatment modality that imparts damage to cellular DNA, induces immunogenic cell death, and activates antitumor immunity. Despite the radiotherapy-induced direct antitumor effect seen within the treated vo…
View article: Data from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
Data from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients Open
Prostate cancer is the most frequently diagnosed solid malignancy in men. African American (AA) men are at greater risk for developing prostate cancer, and experience higher mortality rates, as compared with Caucasian American men. However…
View article: Supplementary Table ST1. from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
Supplementary Table ST1. from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients Open
Table S1. Clinical characterization of prostate cancer patients.
View article: Supplementary Figure SF1 from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
Supplementary Figure SF1 from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients Open
Figure S1: A) Results obtained from analyses of 15 autosomal short tandem repeat (STR) loci identify the male locus amelogenin. The profile of L/P4T is unique. No mouse DNA was detected for this sample. B) Karyotype of AP4T. Of 20 metaphas…
View article: Supplementary Figure SF1 from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
Supplementary Figure SF1 from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients Open
Figure S1: A) Results obtained from analyses of 15 autosomal short tandem repeat (STR) loci identify the male locus amelogenin. The profile of L/P4T is unique. No mouse DNA was detected for this sample. B) Karyotype of AP4T. Of 20 metaphas…
View article: Supplementary Figure SF2. from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
Supplementary Figure SF2. from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients Open
Figure S2. Western analysis of AR and p53. Cells were examined for expression levels of AR and p53 in a set of cell cultures. LNCaP (AR-dependent and p53+) and PC3 (AR-independent and p53 null) cells were used as controls for AR and p53 ex…
View article: Supplementary Figure SF3. from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients
Supplementary Figure SF3. from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients Open
Figure S3: Immunocytochemistry analysis of normal (N) and tumor (T)- derived paired cell cultures of AP4 and AP10. Normal and tumor cells from AP4 and AP10 were stained with indicated antibodies. DAPI (bottom in blue) stained the nucleus. …