Pascal Buijs
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View article: Oncolytic Newcastle Disease Virus as treatment for pancreatic cancer
Oncolytic Newcastle Disease Virus as treatment for pancreatic cancer Open
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\nIn this thesis, experiments are presented that were undertaken to develop oncolytic NDV for the treatment of pancreatic adenocarcinoma. Oncolytic viruses (OVs), reported first halfway the previous century, have und
View article: Recombinant Immunomodulating Lentogenic or Mesogenic Oncolytic Newcastle Disease Virus for Treatment of Pancreatic Adenocarcinoma
Recombinant Immunomodulating Lentogenic or Mesogenic Oncolytic Newcastle Disease Virus for Treatment of Pancreatic Adenocarcinoma Open
Oncolytic Newcastle disease virus (NDV) might be a promising new therapeutic agent for the treatment of pancreatic cancer. We evaluated recombinant NDVs (rNDVs) expressing interferon (rNDV-hIFNβ-F\(_{\rm{0}}\)) or an IFN antagonistic prote…
View article: Oncolytic viruses: From bench to bedside with a focus on safety
Oncolytic viruses: From bench to bedside with a focus on safety Open
Oncolytic viruses are a relatively new class of anti-cancer immunotherapy agents. Several viruses have undergone evaluation in clinical trials in the last decades, and the first agent is about to be approved to be used as a novel cancer th…