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View article: Multiple Organ Failure as a Strong Predictor of Mortality in Patients with Hypoxic Hepatitis
Multiple Organ Failure as a Strong Predictor of Mortality in Patients with Hypoxic Hepatitis Open
Background: Hypoxic hepatitis contributes to the development and progression of multiple organ failure (MOF). We evaluated whether MOF is associated with 30-day mortality in patients with hypoxic hepatitis. Methods: This retrospective stud…
View article: Seoul Consensus on Clinical Practice Guidelines for Functional Constipation
Seoul Consensus on Clinical Practice Guidelines for Functional Constipation Open
Chronic constipation is one of the most common digestive diseases encountered in clinical practice. Constipation manifests as a variety of symptoms, such as infrequent bowel movements, hard stools, feeling of incomplete evacuation, straini…
View article: Etiology and Outcomes of Patients with Extreme Hyperbilirubinemia in Korea: A Retrospective Cohort Study
Etiology and Outcomes of Patients with Extreme Hyperbilirubinemia in Korea: A Retrospective Cohort Study Open
This study suggests three etiologies of extreme hyperbilirubinemia in the ICU and non-ICU settings. The prognosis of patients with extreme hyperbilirubinemia depends largely on the etiology and the presence of obstructive jaundice.
View article: Efficacy of Tegoprazan in Patients With Functional Dyspepsia: A Prospective, Multicenter, Single-arm Study
Efficacy of Tegoprazan in Patients With Functional Dyspepsia: A Prospective, Multicenter, Single-arm Study Open
Tegoprazan (50 mg) administered once daily provided satisfactory symptom relief for FD.
View article: Clinical Trial: Efficacy of Mosapride Controlled-release and Nortriptyline in Patients With Functional Dyspepsia: A Multicenter, Double-placebo, Double-blinded, Randomized Controlled, Parallel Clinical Study
Clinical Trial: Efficacy of Mosapride Controlled-release and Nortriptyline in Patients With Functional Dyspepsia: A Multicenter, Double-placebo, Double-blinded, Randomized Controlled, Parallel Clinical Study Open
Mosapride CR and nortriptyline showed similar efficacy in patients with FD regardless of the subtype. Both treatments could be equally helpful for improving quality of life and psychological well-being while also relieving dyspepsia.
View article: Constipation in Patients With Chronic Kidney Disease
Constipation in Patients With Chronic Kidney Disease Open
Constipation is a frequent symptom in patients with chronic kidney disease (CKD). This review outlines the mechanisms and management of constipation in patients with CKD from a physician’s perspective. Common causes of constipation in pati…
View article: 2022 Seoul Consensus on Clinical Practice Guidelines for Functional Constipation
2022 Seoul Consensus on Clinical Practice Guidelines for Functional Constipation Open
Chronic constipation is one of the most common digestive diseases encountered in clinical practice. Constipation manifests as a variety of symptoms, such as infrequent bowel movements, hard stools, feeling of incomplete evacuation, straini…
View article: Association of the etiology and peak level of markedly elevated aminotransferases with mortality: a multicenter study
Association of the etiology and peak level of markedly elevated aminotransferases with mortality: a multicenter study Open
Background: Markedly elevated aminotransferase levels are commonly encountered among hospitalized patients. However, data regarding the trajectory of enzyme elevation and disease-specific prognosis are limited. Methods: This study included…
View article: Clinical Features of Hepatitis C Virus-related Acute-on-chronic Liver Failure in a Korean Population
Clinical Features of Hepatitis C Virus-related Acute-on-chronic Liver Failure in a Korean Population Open
HCV-related ACLF has unique clinical characteristics distinct from hepatitis B virus-related and alcohol-related ACLF. ACLF defined by EASL can be useful for predicting the short-term mortality in HCV-related cirrhosis.
View article: Self-reported Non-celiac Gluten Sensitivity in the Korean Population: Demographic and Clinical Characteristics
Self-reported Non-celiac Gluten Sensitivity in the Korean Population: Demographic and Clinical Characteristics Open
Our findings suggest that if there are gluten-related symptoms in irritable bowel syndrome, the possibility of accompanying non-celiac gluten sensitivity should be considered.
View article: Clinical Features and Prognosis of Patients with Primary Intestinal B-cell Lymphoma Treated with Chemotherapy with or without Surgery
Clinical Features and Prognosis of Patients with Primary Intestinal B-cell Lymphoma Treated with Chemotherapy with or without Surgery Open
The Ann Arbor stage, hemoglobin level, and histological type were independent prognostic factors for survival, while the primary site of involvement and treatment modality did not affect the prognosis in patients with B-cell PIL.
View article: Acute Hepatitis E Virus Superinfection Increases Mortality in Patients with Cirrhosis
Acute Hepatitis E Virus Superinfection Increases Mortality in Patients with Cirrhosis Open
Background: Although acute hepatitis E is not fatal in healthy individuals, it is unclear whether hepatitis E superinfection increases mortality in patients with pre-existing liver disease. Thus, we investigated the prognosis of patients w…
View article: Impact of non-hepatic hyperammonemia on mortality in intensive care unit patients: a retrospective cohort study
Impact of non-hepatic hyperammonemia on mortality in intensive care unit patients: a retrospective cohort study Open
Background/Aims: The effect of hyperammonemia on the mortality in patients with liver cirrhosis is well documented. However, little is known about the impact of hyperammonemia on mortality among intensive care unit patients without hepatic…
View article: Impact of acute kidney injury on survival in patients with chronic hepatitis C: a retrospective cohort study
Impact of acute kidney injury on survival in patients with chronic hepatitis C: a retrospective cohort study Open
Background Acute kidney injury (AKI) is expected to occur commonly in patients with chronic hepatitis C. In addition, AKI may affect the survival of patients with chronic hepatitis C. However, few studies are available on this topic. We ai…
View article: Clinical Features of Hepatitis C Virus-Related Acute-On-Chronic Liver Failure in a Korean Population
Clinical Features of Hepatitis C Virus-Related Acute-On-Chronic Liver Failure in a Korean Population Open
Background Acute-on-chronic liver failure (ACLF) is a widely recognized concept in which acute decompensation (AD) in patients with cirrhosis results in organ failures and high short-term mortality. However, few studies reflecting the vari…
View article: Impact of Non-Hepatic Hyperammonemia on Mortality in Intensive Care Unit Patients: A Retrospective Cohort Study
Impact of Non-Hepatic Hyperammonemia on Mortality in Intensive Care Unit Patients: A Retrospective Cohort Study Open
Background: The effect of hyperammonemia on the mortality in patients with liver cirrhosis is well documented. However, little is known about the impact of hyperammonemia on mortality in intensive care unit patients without hepatic disease…
View article: Impact of Acute Kidney Injury on Survival in Patients With Chronic Hepatitis C
Impact of Acute Kidney Injury on Survival in Patients With Chronic Hepatitis C Open
Background: Acute kidney injury (AKI) is expected to occur commonly in patients with chronic hepatitis C. In addition, AKI may affect the survival of patients with chronic hepatitis C. However, few studies are available on this topic. We a…
View article: Non-celiac Gluten Sensitivity
Non-celiac Gluten Sensitivity Open
Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improve…
View article: Recent Advances in the Pathogenesis and Treatment of Functional Dyspepsia with Focus on the Duodenum
Recent Advances in the Pathogenesis and Treatment of Functional Dyspepsia with Focus on the Duodenum Open
Article Novel Concepts in the Pathophysiology and Treatment of Functional Dyspepsia (Gut 2019 Nov 29. [Epub ahead of print])
View article: Hepatitis C virus genotype affects survival in patients with hepatocellular carcinoma
Hepatitis C virus genotype affects survival in patients with hepatocellular carcinoma Open
Among patients with HCV-related HCC, those with genotype 2 have better survival.
View article: Self-expanding metal stent procedure for afferent loop syndrome with ascending cholangitis caused by remnant gastric cancer
Self-expanding metal stent procedure for afferent loop syndrome with ascending cholangitis caused by remnant gastric cancer Open
Rationale: Self-expanding metal stent placement is a useful procedure for intestinal obstruction. Afferent loop syndrome after gastrectomy is an uncommon complication of gastroenterostomy reconstruction. Ascending cholangitis caused by aff…
View article: Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience
Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience Open
Most patients responded very well to anti-TB therapy, and surgery was required in only a minority of cases of suspected abdominal TB.
View article: Successful biliary cannulation by the rendezvous technique via percutaneous transhepatic gallbladder drainage: A report of two cases
Successful biliary cannulation by the rendezvous technique via percutaneous transhepatic gallbladder drainage: A report of two cases Open
Key Clinical Message Reports of the rendezvous technique via percutaneous transhepatic gallbladder drainage are very rare because of difficulties with insertion of the guidewire from the gallbladder into the common bile duct. In particular…
View article: Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report Open
Small cell carcinomas are the most aggressive, highly malignant neuroendocrine tumors; among these, gastric small cell carcinoma (GSCC) is extremely rare. Here we report a case of a patient with primary GSCC, presenting as linitis plastic,…
View article: Endoscopic submucosal dissection under general anesthesia for superficial esophageal squamous cell carcinoma is associated with better clinical outcomes
Endoscopic submucosal dissection under general anesthesia for superficial esophageal squamous cell carcinoma is associated with better clinical outcomes Open
ESD is an oncologically effective treatment modality for SESCC, particularly when CuR is achieved. Applying GA for esophageal ESD could improve the clinical outcomes of ESD in patients with SESCC.