Regina Silva
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View article: CGRP Suppresses Protective SiglecFhi Neutrophil Development in Neonatal Group B Streptococcus Pneumonia
CGRP Suppresses Protective SiglecFhi Neutrophil Development in Neonatal Group B Streptococcus Pneumonia Open
Neonatal pneumonia, a leading cause of morbidity and mortality, is frequently caused by Group B Streptococcus (GBS). The mechanisms underlying protective immunity to this pathogen in the neonatal lung remain incompletely understood. Using …
View article: Análise de correlação das manifestações patológicas em fachadas de prédio caixão
Análise de correlação das manifestações patológicas em fachadas de prédio caixão Open
Objective – Identify and analyze the pathological manifestations on box buildings with painted coatings facades, as well as carry out a correlation analysis to understand the relationships between these structural problems. Methodology – T…
View article: 0030 Sleep Regularity Index and Light Regularity Index in Six-month-old Infants
0030 Sleep Regularity Index and Light Regularity Index in Six-month-old Infants Open
Introduction There is a bidirectional relationship between sleep patterns and light exposure patterns; in other words, sleep patterns influence light exposure patterns, and vice versa. Sleep regularity can be quantified using the Sleep Reg…
View article: Ambulatory inguinal hernia repair in Portugal - a multicenter prospective cohort study
Ambulatory inguinal hernia repair in Portugal - a multicenter prospective cohort study Open
Ambulatory surgery is the recommended approach for elective inguinal hernia repair for most people. However, the relative use of this procedure in Portugal and its related outcomes are unknown. We aimed to assess complication rates in pati…
View article: Análise dos danos estruturais e necessidades de manutenção em um prédio caixão
Análise dos danos estruturais e necessidades de manutenção em um prédio caixão Open
The article analyzes the structural damage and maintenance needs of a coffin building in Jaboatão dos Guararapes-PE, highlighting the importance of preserving the integrity of buildings with pathological manifestations. In order to create …
View article: Interdisciplinary management of orofacial lesions in early childhood: paediatric alert system at University of Verona.
Interdisciplinary management of orofacial lesions in early childhood: paediatric alert system at University of Verona. Open
Orofacial trauma (OFT) occurs frequently in children and requires thorough evaluation not only by paediatric dentists but also by all specialists involved in emergency services, particularly in cases involving children under 3 years of age…
View article: The Project Trauma-Informed Practice for Workers in Public Service Settings: New Strategies for the Same Old Objective
The Project Trauma-Informed Practice for Workers in Public Service Settings: New Strategies for the Same Old Objective Open
Many professionals are confronted in their practice with clients who show post-traumatic symptoms (PTS). “Trauma-informed practice” helps professionals recognize, understand, and appropriately respond to the effects of trauma. This work pr…
View article: Necrotizing Enterocolitis: Incidence, Risk Factors, and Associated Morbidities in a Large Cohort of Infants with Very Low Birth Weight
Necrotizing Enterocolitis: Incidence, Risk Factors, and Associated Morbidities in a Large Cohort of Infants with Very Low Birth Weight Open
Objective: Necrotizing Enterocolitis (NEC) causes morbidity and mortality in infancy.This study investigated the incidence, risk factors, morbidity, and mortality rates in a cohort of infants with very low birth weight in Brazil.Study Desi…
View article: Epidemiology of prematurity and related comorbidities in very low birth weight preterm newborns
Epidemiology of prematurity and related comorbidities in very low birth weight preterm newborns Open
OBJECTIVE: To describe the major epidemiological features of prematurity, risk factors, prevalence of comorbidities, death and survival rates in very low birth weight newborns. METHODS: Transversal study with rectrospective data collection…
View article: Epidemiology of prematurity and related comorbidities in very low birth weight preterm newborns
Epidemiology of prematurity and related comorbidities in very low birth weight preterm newborns Open
Objective: To describe the major epidemiological features of prematurity, risk factors, prevalence of comorbidities, death and survival rates in very low birth weight newborns. Methods: Transversal study with rectrospective data collection…
View article: High-risk HPV genotypes and cervical lesions association in postmenopausal women
High-risk HPV genotypes and cervical lesions association in postmenopausal women Open
Background Persistent infection by high-risk Human Papillomavirus (hrHPV) are the major cause of cervical cancer. Studies report disparities in the incidence of infection and the various genotypes of this virus in different age groups, sug…
View article: Family caregiver support—a facilitator to empower family caregivers
Family caregiver support—a facilitator to empower family caregivers Open
Background Mental disorders are highly prevalent, placing an enormous burden on individuals, society and economy. Research shows that family members who provide care to individuals with chronic or disabling mental conditions are themselves…
View article: Maternal deprivation by early weaning causesthe nociceptinto alter the palatability and cookie consumption
Maternal deprivation by early weaning causesthe nociceptinto alter the palatability and cookie consumption Open
The deprivation of maternal care during the initial development period, as well as interruption of early breastfeeding, promotes changes in eating behavior, however, the underlying neuromodulatory mechanisms have not been fully understood.…
View article: Validation of CINtec® PLUS Cytology Kit in the Diagnosis of Persistent HPV Infections - Cohort Study in the Portuguese Population
Validation of CINtec® PLUS Cytology Kit in the Diagnosis of Persistent HPV Infections - Cohort Study in the Portuguese Population Open
Context: The use of the CINtec® PLUS Cytology Kit as a complementary method of diagnosis is intended to contribute to a risk assessment of CIN II+ cervical lesions development, thus avoiding unnecessary colposcopy in negative cases. This m…
View article: The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines Open
Breast (BrCa) and prostate (PCa) cancers are the most common malignancies in women and men, respectively. The available therapeutic options for these tumors are still not curative and have severe side effects. Therefore, there is an urgent…
View article: Expression of EMT-Related Genes CAMK2N1 and WNT5A is increased in Locally Invasive and Metastatic Prostate Cancer
Expression of EMT-Related Genes CAMK2N1 and WNT5A is increased in Locally Invasive and Metastatic Prostate Cancer Open
Purpose: Prostate cancer (PCa) varies clinically from very indolent, not requiring therapeutic intervention, to highly aggressive, entailing radical treatment. Currently, stratification of PCa aggressiveness is mostly based on Gleason scor…
View article: Laparoscopic deroofing of a ruptured hepatic cyst presenting as an acute abdomen
Laparoscopic deroofing of a ruptured hepatic cyst presenting as an acute abdomen Open
The rupture of a nonparasitic hepatic cyst is a rare complication for which there is no optimal treatment strategy yet. Laparoscopic deroofing is the standard approach for the elective treatment of symptomatic NHCs but it has seldom been d…
View article: Prevalence of pancreatic autoantibodies in non-diabetic patients with autoimmune thyroid disease and its relation to insulin secretion and glucose tolerance
Prevalence of pancreatic autoantibodies in non-diabetic patients with autoimmune thyroid disease and its relation to insulin secretion and glucose tolerance Open
Objective We evaluated the prevalence of glutamic acid decarboxylase (GADA) and tyrosine phosphatase-protein antibodies (IA2A), their titers and their relation to first phase insulin response (FPIR) and glucose tolerance in autoimmune thyr…
View article: Prevalence of pancreatic autoantibodies in non-diabetic patients with autoimmune thyroid disease and its relation to insulin secretion and glucose tolerance
Prevalence of pancreatic autoantibodies in non-diabetic patients with autoimmune thyroid disease and its relation to insulin secretion and glucose tolerance Open
A trend for greater prevalence of GADA was observed for GD patients than for HT or control. However, the titers of these autoantibodies were higher in HT patients, but there was no significant relation to insulin secretion and glucose tole…
View article: Diabetic Nephropathy and its two phenotypes: the proteinuric and non-proteinuric
Diabetic Nephropathy and its two phenotypes: the proteinuric and non-proteinuric Open
The typical progression of diabetic nephropathy is from the normoalbuminuric stage to microalbuminuria (urinary albumin creatinine rate, UACR, 30-300 mg/g) to end in overt proteinuria. A growing body of recent evidence has shown an acceler…
View article: Reaction of common bean lines to Pseudocercospora griseola in different enviromental conditions.
Reaction of common bean lines to Pseudocercospora griseola in different enviromental conditions. Open
This study aimed to compare the reaction of common bean lines to Pseudocercospora griseola in different enviromental conditions.