Rashidul Haque
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View article: A framework for guiding integrated disease control measures through multipathogen surveillance
A framework for guiding integrated disease control measures through multipathogen surveillance Open
Global health programs have traditionally focused on single diseases. There is potential for synergy through integrated intervention delivery, particularly in areas with overlapping geographic disease burden, but there is limited methodolo…
View article: Effect of neonatal administration of <i>Lactiplantibacillus plantarum</i> ATCC 202195 on stool iron content and iron status in infants in Dhaka, Bangladesh
Effect of neonatal administration of <i>Lactiplantibacillus plantarum</i> ATCC 202195 on stool iron content and iron status in infants in Dhaka, Bangladesh Open
Background Lactobacillus probiotics may enhance host iron bioavailability, offering a potential strategy to address iron deficiency; however, evidence of such effects in infants is lacking. Objective To examine whether neonatal administrat…
View article: Effects of a single oral dose of azithromycin in laboring women on antimicrobial resistance (AMR) and the microbiome: a protocol for the Antimicrobial Resistance Sub-Study of the A-PLUS trial
Effects of a single oral dose of azithromycin in laboring women on antimicrobial resistance (AMR) and the microbiome: a protocol for the Antimicrobial Resistance Sub-Study of the A-PLUS trial Open
Background The Azithromycin Prevention in Labor Use Study (A-PLUS), a large, multi-national randomized trial, was performed to evaluate the improvement of maternal and newborn outcomes following a single dose of azithromycin (AZ) given dur…
View article: Impact of Asymptomatic Enteroaggregative <i>Escherichia coli</i> Infection and Co-Pathogen Burden on Intestinal Barrier Function, Linear Growth, and Cognitive Development in Early Childhood: Insights from a Birth Cohort Study
Impact of Asymptomatic Enteroaggregative <i>Escherichia coli</i> Infection and Co-Pathogen Burden on Intestinal Barrier Function, Linear Growth, and Cognitive Development in Early Childhood: Insights from a Birth Cohort Study Open
Introduction Enteroaggregative Escherichia coli (EAEC) is a major enteric pathogen in low-resource settings and can infect children with or without causing diarrhea. However, limited data exists on the impact of subclinical EAEC infections…
View article: The cAMP responsive element modulator (CREM) transcription factor influences susceptibility to undernutrition and infection
The cAMP responsive element modulator (CREM) transcription factor influences susceptibility to undernutrition and infection Open
We previously identified genetic polymorphisms associated with Entamoeba histolytica -positive diarrhea at the locus containing the transcription factor, cAMP responsive element modulator ( CREM ). Genetic association testing in birth coho…
View article: Decrease in Incidence of Diarrhea Due to <i>Cryptosporidium</i> in Bangladeshi Children Is Associated With an Increase in Anti-<i>Cryptosporidium</i> Antibody Avidity
Decrease in Incidence of Diarrhea Due to <i>Cryptosporidium</i> in Bangladeshi Children Is Associated With an Increase in Anti-<i>Cryptosporidium</i> Antibody Avidity Open
Background Cryptosporidium is a cause of diarrhea morbidity and mortality in infants in low- and middle-income countries. Methods A cohort of children was followed longitudinally in a high-transmission-intensity community in Bangladesh. Re…
View article: Health care in pregnancy during the COVID‐19 pandemic and pregnancy outcomes in six low‐ and‐middle‐income countries: Evidence from a prospective, observational registry of the Global Network for Women’s and Children’s Health
Health care in pregnancy during the COVID‐19 pandemic and pregnancy outcomes in six low‐ and‐middle‐income countries: Evidence from a prospective, observational registry of the Global Network for Women’s and Children’s Health Open
OBJECTIVE: To assess, on a population basis, the medical care for pregnant women in specific geographic regions of six countries before and during the first year of the coronavirus disease 2019 (COVID-19) pandemic in relationship to pregna…
View article: Knowledge, attitude and practices of pregnant women related to COVID‐19 infection: A cross‐sectional survey in seven countries from the Global Network for Women's and Children's Health
Knowledge, attitude and practices of pregnant women related to COVID‐19 infection: A cross‐sectional survey in seven countries from the Global Network for Women's and Children's Health Open
Objective: We sought to understand knowledge, attitudes and practices (KAP) regarding COVID-19 in pregnant women in seven low and middle-income countries (LMIC). Design: Population-based prospective, observational study. Settings: Study si…
View article: Epidemiology of Shigella species and serotypes in children: a retrospective substudy of the MAL-ED observational birth cohort study
Epidemiology of Shigella species and serotypes in children: a retrospective substudy of the MAL-ED observational birth cohort study Open
Bill & Melinda Gates Foundation.
View article: Gastrointestinal and hepatobiliary manifestations of COVID-19 infection: A single center study from Pakistan
Gastrointestinal and hepatobiliary manifestations of COVID-19 infection: A single center study from Pakistan Open
BACKGROUND: Coronavirus disease was a global challenge affecting around 229 countries with over 700 million confirmed cases with significant morbidity and mortality. OBJECTIVE: To determine the frequency of hepatobiliary manifestations in …
View article: COVID‐19 antibody positivity over time and pregnancy outcomes in seven low‐and‐middle‐income countries: A prospective, observational study of the Global Network for Women's and Children's Health Research
COVID‐19 antibody positivity over time and pregnancy outcomes in seven low‐and‐middle‐income countries: A prospective, observational study of the Global Network for Women's and Children's Health Research Open
OBJECTIVES: To determine COVID-19 antibody positivity rates over time and relationships to pregnancy outcomes in low- and middle-income countries (LMICs). DESIGN: With COVID-19 antibody positivity at delivery as the exposure, we performed …
View article: NTDscope: A multi-contrast portable microscope for disease diagnosis
NTDscope: A multi-contrast portable microscope for disease diagnosis Open
Accurate diagnostics are essential for disease control and elimination efforts. However, access to diagnostics for neglected tropical diseases (NTDs) is hindered by limited healthcare infrastructure in many NTD-endemic regions, as well as …
View article: Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children
Influence of environmental exposures on T follicular helper cell function and implications on immunity: a comparison of Bangladeshi and American children Open
T follicular helper (Tfh) cells are crucial for B cell activation and subsequent antibody production. This functionality is influenced by surface markers such as CD40L, a costimulatory factor which promotes B cell activation, and CD57, whi…
View article: Learning Styles, Preferences and Needs of Generation Z Medical Students
Learning Styles, Preferences and Needs of Generation Z Medical Students Open
Background: Generation Z individuals have been described as being technologically sophisticated, dependent on gadgets and devices, have short attention spans, dislike reading printed material, prefer collaborative activities and learning i…
View article: High Exposure to Screen: A threat for Health and Mental Wellbeing of School Going Children in Dhaka, Bangladesh (Preprint)
High Exposure to Screen: A threat for Health and Mental Wellbeing of School Going Children in Dhaka, Bangladesh (Preprint) Open
BACKGROUND In Bangladesh as well as throughout the world, children's screen time has significantly increased. Children spent a lot of time on the internet and digital screens for entertainment, education, and communication which have incr…
View article: Assessment of cellular immune phenotype of peripheral blood mononuclear cells in Bangladeshi children with severe acute malnutrition
Assessment of cellular immune phenotype of peripheral blood mononuclear cells in Bangladeshi children with severe acute malnutrition Open
Children suffering from severe acute malnutrition (SAM) have a weakened immune system. The relationship between malnutrition and alterations in the frequency of peripheral blood mononuclear cells (PBMCs) remains unclear. This study investi…
View article: Effects of household concrete floors on maternal and child health: the CRADLE trial – a randomised controlled trial protocol
Effects of household concrete floors on maternal and child health: the CRADLE trial – a randomised controlled trial protocol Open
Introduction Early life soil-transmitted helminth (STH) infection and diarrhoea are associated with growth faltering, anaemia, impaired child development and mortality. Exposure to faecally contaminated soil inside the home may be a key co…
View article: Effect of Nitazoxanide and Probiotic Treatment on Bangladeshi Children with Cryptosporidiosis
Effect of Nitazoxanide and Probiotic Treatment on Bangladeshi Children with Cryptosporidiosis Open
Cryptosporidium spp. is a cause of diarrhea morbidity and mortality in children under 5 years of age. In addition, asymptomatic infections can have a negative impact on growth and development. In low- and middle-income countries where a gr…
View article: Bile acid dysmetabolism in Bangladeshi infants is associated with poor linear growth, enteric inflammation, and small intestine bacterial overgrowth
Bile acid dysmetabolism in Bangladeshi infants is associated with poor linear growth, enteric inflammation, and small intestine bacterial overgrowth Open
Introduction Environmental enteric dysfunction (EED) is a subclinical condition caused by fecal-oral contamination leading to enteric inflammation and dysbiosis. This study investigates bile acid metabolism in Bangladeshi children with EED…
View article: Antibodies Against SARS-CoV-2 Do Not Cross-React with Endemic Coronaviruses in a Pediatric Population: Data from a Bangladesh Cohort
Antibodies Against SARS-CoV-2 Do Not Cross-React with Endemic Coronaviruses in a Pediatric Population: Data from a Bangladesh Cohort Open
There is a limited understanding of the immunological differences between children and adults that protect children from developing severe coronavirus disease 2019 (COVID-19) following SARS-CoV-2 infection. Previous infection with endemic …
View article: Evaluation of the In vitro Anthelmintic Activity of Melia azedarach and Swertia chirata Aqueous Extracts Against Haemonchus contortus
Evaluation of the In vitro Anthelmintic Activity of Melia azedarach and Swertia chirata Aqueous Extracts Against Haemonchus contortus Open
Aim: This research intended to assess the in vitro anthelmintic properties of Mahaneem leaves (Melia azedarach) and whole plant of Chirata (Swertia chirata). Study Design: In vitro study was conducted aganist Haemonchus contortus eggs and …
View article: Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition
Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition Open
Malnutrition affects over 30 million children annually and has profound immediate and enduring repercussions. Survivors often suffer lasting neurocognitive consequences that impact academic performance and socioeconomic outcomes. Mechanist…
View article: Predicting Stunted Growth in Two Year Old Bangladeshi Children via the Super Learner
Predicting Stunted Growth in Two Year Old Bangladeshi Children via the Super Learner Open
Stunted growth in children is a worldwide issue which may cause long term problems for individuals stunted as early as two years of age. However, predicting stunted growth with accuracy is quite complex, but machine learning poses a distin…