Rachael E. Rush
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View article: LRP1 facilitates Jamestown Canyon virus infection of neurons
LRP1 facilitates Jamestown Canyon virus infection of neurons Open
Jamestown Canyon virus (JCV) is a bunyavirus and arbovirus that causes viral neuroinvasive disease in North America. JCV neuropathogenesis is understudied, and no pro-viral host factors for cellular infection have been identified. Here, we…
View article: Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor
Identification and Characterization of a Metal Binding-Independent Rift Valley Fever Virus Endonuclease Inhibitor Open
The viral cap-snatching mechanism, facilitated by the endonuclease (EndoN) domain of viral polymerases, is critical for viral gene transcription and translation and is therefore an attractive target for antiviral development. The successfu…
View article: Lrp1 facilitates infection of neurons by Jamestown Canyon virus
Lrp1 facilitates infection of neurons by Jamestown Canyon virus Open
Jamestown Canyon virus (JCV) is a bunyavirus and arbovirus responsible for neuroinvasive disease in the United States. Little is known about JCV pathogenesis, and no host factors required for cellular infection have been identified. Recent…
View article: Corrigendum: Persisting Cryptococcus yeast species Vishniacozyma victoriae and Cryptococcus neoformans elicit unique airway inflammation in mice following repeated exposure
Corrigendum: Persisting Cryptococcus yeast species Vishniacozyma victoriae and Cryptococcus neoformans elicit unique airway inflammation in mice following repeated exposure Open
[This corrects the article DOI: 10.3389/fcimb.2023.1067475.].
View article: Optimization of Aspergillus versicolor Culture and Aerosolization in a Murine Model of Inhalational Fungal Exposure
Optimization of Aspergillus versicolor Culture and Aerosolization in a Murine Model of Inhalational Fungal Exposure Open
Aspergillus versicolor is ubiquitous in the environment and is particularly abundant in damp indoor spaces. Exposure to Aspergillus species, as well as other environmental fungi, has been linked to respiratory health outcomes, including as…
View article: Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice
Lrp1 is essential for lethal Rift Valley fever hepatic disease in mice Open
Rift Valley fever virus (RVFV) is an emerging arbovirus found in Africa. While RVFV is pantropic and infects many cells and tissues, viral replication and necrosis within the liver play a critical role in mediating severe disease. The low-…
View article: Persisting Cryptococcus yeast species Vishniacozyma victoriae and Cryptococcus neoformans elicit unique airway inflammation in mice following repeated exposure
Persisting Cryptococcus yeast species Vishniacozyma victoriae and Cryptococcus neoformans elicit unique airway inflammation in mice following repeated exposure Open
Background Allergic airway disease (AAD) is a growing concern in industrialized nations and can be influenced by fungal exposures. Basidiomycota yeast species such as Cryptococcus neoformans are known to exacerbate allergic airway disease;…
View article: Ten questions concerning the implications of carpet on indoor chemistry and microbiology
Ten questions concerning the implications of carpet on indoor chemistry and microbiology Open
Carpet and rugs currently represent about half of the United States flooring market and offer many benefits as a flooring type. How carpets influence our exposure to both microorganisms and chemicals in indoor environments has important he…
View article: Function, expression, specificity, diversity and incompatibility of actinobacteriophage <i>parABS</i> systems
Function, expression, specificity, diversity and incompatibility of actinobacteriophage <i>parABS</i> systems Open
Summary More than 180 individual phages infecting hosts in the phylum Actinobacteria have been sequenced and grouped into Cluster A because of their similar overall nucleotide sequences and genome architectures. These Cluster A phages are …