Rachel Debs
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View article: Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case-Control Study and Call for a Consensus
Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case-Control Study and Call for a Consensus Open
Objective: Sleep-predominant network hyperexcitability is increasingly recognized as a potential disease-accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk-factors remain debated, largely due to cohort-s…
View article: Stridor Is an Independent Risk Factor for Mortality and Disease Progression in Patients with Multiple System Atrophy
Stridor Is an Independent Risk Factor for Mortality and Disease Progression in Patients with Multiple System Atrophy Open
Background and aim Stridor and sleep apnea syndrome (SAS) are common in multiple system atrophy (MSA). Retrospective cohort studies have yielded conflicting results regarding the consequences of stridor and SAS on the disease course. This …
View article: Determinants of substance use patterns in patients with narcolepsy type 1: A multi-center comparative cross-sectional study
Determinants of substance use patterns in patients with narcolepsy type 1: A multi-center comparative cross-sectional study Open
Patients with NT1 do not seem less vulnerable to psychoactive substance use/misuse. Consumptions patterns are associated with multiple dimensions of the disease including sleep-related symptoms, comorbidities, treatments, and psycho-behavi…
View article: Back to the future: May Kleine‐Levin syndrome be an emerging psychiatric disorder?
Back to the future: May Kleine‐Levin syndrome be an emerging psychiatric disorder? Open
Since the 20th century, atypical cases of recurrent hypersomnia are no longer related to mood disorders but are grouped together in the new Kleine-Levin syndrome (KLS). Between neurology and psychiatry, the KLS symptoms include hypersomnia…
View article: Microglia Density and Its Association With Disease Duration, Severity, and Orexin Levels in Patients With Narcolepsy Type 1
Microglia Density and Its Association With Disease Duration, Severity, and Orexin Levels in Patients With Narcolepsy Type 1 Open
ClinicalTrials.org NCT03754348.
View article: Academic and socio-professional trajectories in narcolepsy type 1: the NARCOSCOL-NARCOVITAE multicentric study
Academic and socio-professional trajectories in narcolepsy type 1: the NARCOSCOL-NARCOVITAE multicentric study Open
Background and objectives Narcolepsy type 1 (NT1) is a chronic, disabling neurological disease. Sleep-related symptoms and comorbidities such as psycho-cognitive disturbances, and a frequent childhood onset of the disease may negatively im…
View article: Specific profiles of new-onset vs. non-inaugural status epilepticus: From diagnosis to 1-year outcome
Specific profiles of new-onset vs. non-inaugural status epilepticus: From diagnosis to 1-year outcome Open
While new-onset status epilepticus (NOSE) is a harbinger of chronic epilepsy, prospective medical data are sparse in terms of specifying whether the evolution of status epilepticus (SE) and seizure expression in NOSE resembles what occurs …
View article: Erdheim-Chester Disease Revealed by Central Positional Nystagmus: A Case Report
Erdheim-Chester Disease Revealed by Central Positional Nystagmus: A Case Report Open
Erdheim-Chester disease (ECD) is a rare histiocytic disorder, recently recognized to be neoplastic. The clinical phenotype of the disease is extremely heterogeneous, and depends on the affected organs, with the most frequently reported man…