Rachel Gorodkin
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View article: Psoriatic arthritis: the role of self-reported non-adherence, non-trough drug levels, immunogenicity and conventional synthetic DMARD co-therapy in adalimumab and etanercept response
Psoriatic arthritis: the role of self-reported non-adherence, non-trough drug levels, immunogenicity and conventional synthetic DMARD co-therapy in adalimumab and etanercept response Open
Objective The aim of this study was to assess the relationship between self-reported non-adherence, non-trough drug levels, immunogenicity and conventional synthetic DMARD (csDMARD) co-therapy in TNF inhibitor (TNF-i) drug response in PsA.…
View article: Non-trough serum drug levels of adalimumab and etanercept are associated with response in patients with psoriatic arthritis
Non-trough serum drug levels of adalimumab and etanercept are associated with response in patients with psoriatic arthritis Open
Objectives Up to 40% of PsA patients experience first-line tumour necrosis factor inhibitors (TNF-i) failure. Lower serum drug levels (SDL) have been associated with lower response in autoimmune conditions. This study aimed to: (i) establi…
View article: P209 Subgroups of refractory rheumatoid arthritis and difficult to treat features highlight differences in comorbidity and smoking history - a single-centre observational study
P209 Subgroups of refractory rheumatoid arthritis and difficult to treat features highlight differences in comorbidity and smoking history - a single-centre observational study Open
Background/Aims Limited therapeutic efficacy and ‘difficult to treat’ (D2T) characteristics mean some rheumatoid arthritis (RA) patients cycle through multiple therapies to achieve their treatment targets. The aim of this study was to eval…
View article: Translating research into clinical practice: quality improvement to halve non-adherence to methotrexate
Translating research into clinical practice: quality improvement to halve non-adherence to methotrexate Open
Objective MTX remains the cornerstone for therapy for RA, yet research shows that non-adherence is significant and correlates with response to therapy. This study aimed to halve self-reported non-adherence to MTX at the Kellgren Centre for…
View article: 9. Hypomyopathic dermatomyositis complicated by mannose-binding lectin deficiency
9. Hypomyopathic dermatomyositis complicated by mannose-binding lectin deficiency Open
Introduction Connective tissue diseases can present a diagnostic odyssey both for the patient and the practitioner. Here, the clinical journey of a patient with hypomyopathic dermatomyositis and mannose-binding lectin deficiency is describ…
View article: Progression of subclinical and clinical cardiovascular disease in a UK SLE cohort: the role of classic and SLE-related factors
Progression of subclinical and clinical cardiovascular disease in a UK SLE cohort: the role of classic and SLE-related factors Open
Objectives We aimed to describe the rate and determinants of carotid plaque progression and the onset of clinical cardiovascular disease (CVD) in a UK SLE cohort. Methods Female patients with SLE of white British ancestry were recruited fr…
View article: 078 Peer review in rheumatology members survey
078 Peer review in rheumatology members survey Open
the British Society of Rheumatology Biologics Registry for Rheumatoid Arthritis (BSRBR-RA).The LIP -control arm consisted of the other two sites in the trust, where switching was undertaken at routine clinic review.Funding for the HIP aros…
View article: Microvascular Response in Patients with Complex Regional Pain Syndrome as Measured by Laser Doppler Imaging
Microvascular Response in Patients with Complex Regional Pain Syndrome as Measured by Laser Doppler Imaging Open
Objectives Our aim was to investigate the hypothesis that microvascular dysfunction occurs in patients with CRPS. Specifically, whether there were functional differences in either deeper cutaneous blood vessels or more superficial nutritiv…
View article: 015 Red Cell Aplasia: A Rare Complication of Adult Onset Still's Disease
015 Red Cell Aplasia: A Rare Complication of Adult Onset Still's Disease Open
Background: We present a case of pure red cell aplasia (PRCA) secondary to adult-onset Still's disease (AOSD) to raise awareness of this rare complication.To our knowledge, only seven cases have been reported.RA and SLE have established as…