Rachelle Saleh
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View article: Spastin regulates ER-mitochondrial contact sites and mitochondrial homeostasis
Spastin regulates ER-mitochondrial contact sites and mitochondrial homeostasis Open
Mitochondria-endoplasmic reticulum (ER) contact sites (MERCs) emerged to play critical roles in numerous cellular processes, and their dysregulation has been associated to neurodegenerative disorders. Mutations in the SPG4 gene coding for …
View article: Potential antiviral effects of pantethine against SARS-CoV-2
Potential antiviral effects of pantethine against SARS-CoV-2 Open
SARS-CoV-2 interacts with cellular cholesterol during many stages of its replication cycle. Pantethine was reported to reduce total cholesterol levels and fatty acid synthesis and potentially alter different processes that might be involve…