Radim J. Šrám
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View article: Biomarkers of exposure to polycyclic aromatic hydrocarbons in urine of municipal police officers: impact of inhalation on total exposure
Biomarkers of exposure to polycyclic aromatic hydrocarbons in urine of municipal police officers: impact of inhalation on total exposure Open
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants that adversely affect human health, mainly through their carcinogenic and mutagenic properties. Monitoring the exposure to PAHs of the inhabitants of air pol…
View article: Possible relationship between respiratory diseases and urinary concentrations of polycyclic aromatic hydrocarbon metabolites - a pilot study
Possible relationship between respiratory diseases and urinary concentrations of polycyclic aromatic hydrocarbon metabolites - a pilot study Open
This study investigates the potential relationship between exposure to polycyclic aromatic hydrocarbons (PAHs), specifically monohydroxylated metabolites (OH-PAHs), in urine, and the prevalence of respiratory diseases in 2-year-old childre…
View article: Prenatal exposure to polycyclic aromatic hydrocarbons and growth parameters
Prenatal exposure to polycyclic aromatic hydrocarbons and growth parameters Open
We have shown a possible connection between higher concentration of OH-PAH metabolites in newborns' urine and decreased length, head circumference, placenta weight, and Apgar 5', but not birth weight.
View article: A Simultaneous Determination of Benzophenone and Camphor UV-Filters, Together with Metabolites of Polycyclic Aromatic Hydrocarbons, in Human Urine
A Simultaneous Determination of Benzophenone and Camphor UV-Filters, Together with Metabolites of Polycyclic Aromatic Hydrocarbons, in Human Urine Open
By monitoring biomarkers in urine, personal exposure to selected chemical substances can be assessed. In this paper, we describe the monitoring of 7 benzophenone and 2 camphor UV-filters and 11 metabolites of polycyclic aromatic hydrocarbo…
View article: Assessment of organohalogenated pollutants in breast milk from the Czech Republic
Assessment of organohalogenated pollutants in breast milk from the Czech Republic Open
This biomonitoring survey brings new information on the occurrence of a total of 94 organohalogenated pollutants in 231 human breast milk samples collected in 2019 and 2021 from women living in two regions of the Czech Republic (Karvina an…
View article: Morbidity of children under 2 years of age in the districts with different degrees of air pollution
Morbidity of children under 2 years of age in the districts with different degrees of air pollution Open
Byla studována nemocnost 300 dětí od narození do 2 let v okresech Karviná (KI) a České Budějovice (CB), lišících se stupněm znečištění ovzduší. Podle očekávání byly více nemocné děti v okrese Karviná, nejčastější byly infekce horních cest …
View article: Maternal Diet Quality and the Health Status of Newborns
Maternal Diet Quality and the Health Status of Newborns Open
The maternal diet during pregnancy affects neonatal health status. The objective of this study was to assess the nutritional quality of the maternal diet, and its contamination by persistent organic pollutants (POPs), in pregnant women liv…
View article: Possible Relationship between Respiratory Diseases and Urinary Concentrations of Polycyclic Aromatic Hydrocarbon Metabolites
Possible Relationship between Respiratory Diseases and Urinary Concentrations of Polycyclic Aromatic Hydrocarbon Metabolites Open
Aim: Exposure to polycyclic aromatic hydrocarbons (PAHs) has been in the past associated with adverse effects on human health among which belong also respiratory diseases. Our study is focused on the evaluation of PAH exposure by measuring…
View article: Possibilities of Influencing Procedural Pain Associated with Premature Newborn Retinopathy Screening with Oral Clonidine
Possibilities of Influencing Procedural Pain Associated with Premature Newborn Retinopathy Screening with Oral Clonidine Open
Background: The aim of our study was to compare the analgesic/sedative effects of various fundus-related procedural pain management strategies on the risk of retinopathy in premature infants. Method: This was a prospective comparative stud…
View article: Prenatal Exposure to Polycyclic Aromatic Hydrocarbons and Growth Parameters
Prenatal Exposure to Polycyclic Aromatic Hydrocarbons and Growth Parameters Open
Background and objectives: The impact of prenatal exposure to polycyclicaromatic 17 hydrocarbons (PAHs) on birth outcomes as weight, length, head circumference, placenta 18 weight, and Apgar. Materials and Methods: Two cohorts of children …
View article: Prenatal Exposure to Polycyclic Aromatic Hydrocarbons and Birth Outcomes
Prenatal Exposure to Polycyclic Aromatic Hydrocarbons and Birth Outcomes Open
Background and objectives: The impact of prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) to birth outcomes as weight, length, head perimeter, placenta weight and Apgar score. Materials and Methods: Two cohorts of children born…
View article: "The Impact of Breastfeeding to Cognitive Functions in 5 Years Old Children"
"The Impact of Breastfeeding to Cognitive Functions in 5 Years Old Children" Open
Barbora Blazkova1, Anna Pastorkova1,2, Ivo Solansky1, Jana Schmuczerova3, Milos Veleminsky, Jr1,4, Milos Veleminsky1 and Radim J Sram1,2* Author Affiliations 1Faculty of Health and Social Sciences, University of South Bohemia, Czech Republ…
View article: Frequency of Leiden Mutation in Newborns with Birth Weight below 1500 g
Frequency of Leiden Mutation in Newborns with Birth Weight below 1500 g Open
It has been hypothesized that fetal prematurity or Intrauterine Growth Restriction (IUGR) could be related to the presence of factor V of Leiden mutation. This mutation is associated with a higher incidence of pregnancy difficulties that c…
View article: Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants
Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants Open
We aimed to identify the variables that modify levels of oxidatively damaged DNA and lipid peroxidation in subjects living in diverse localities of the Czech Republic (a rural area, a metropolitan locality, and an industrial region). The s…
View article: Genome-Wide DNA Methylation in Policemen Working in Cities Differing by Major Sources of Air Pollution
Genome-Wide DNA Methylation in Policemen Working in Cities Differing by Major Sources of Air Pollution Open
DNA methylation is the most studied epigenetic mechanism that regulates gene expression, and it can serve as a useful biomarker of prior environmental exposure and future health outcomes. This study focused on DNA methylation profiles in a…
View article: The Consequences of Various Types of Environments and Their Changes on the Cytogenetic Endpoints Affected by Epigenetic Settings
The Consequences of Various Types of Environments and Their Changes on the Cytogenetic Endpoints Affected by Epigenetic Settings Open
View article: Lifetime Carcinogenic Risk Proportions from Inhalation Exposures in Industrial and Non-Industrial Regions
Lifetime Carcinogenic Risk Proportions from Inhalation Exposures in Industrial and Non-Industrial Regions Open
The aim of this work was to estimate the share of selected significant risk factors for respiratory cancer in the overall incidence of this disease and their comparison in two environmentally different burdened regions. A combination of a …
View article: Evaluation of Fine and Ultrafine Particles Proportion in Airborne Dust in an Industrial Area
Evaluation of Fine and Ultrafine Particles Proportion in Airborne Dust in an Industrial Area Open
The health impacts of suspended particulate matter (SPM) are significantly associated with size—the smaller the aerosol particles, the stronger the biological effect. Quantitative evaluation of fine and ultrafine particles (FP and UFP) is,…
View article: Short- and medium-chain chlorinated paraffins in human blood serum of Czech population
Short- and medium-chain chlorinated paraffins in human blood serum of Czech population Open
Short- and medium-chain chlorinated paraffins (SCCPs; MCCPs) are widespread environmental pollutants with bioaccumulation potential and adverse effects on human health. The analysis of blood serum is an important strategy to assess the hum…
View article: High NO2 Concentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate?
High NO2 Concentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate? Open
This work examines the effects of two problematic trends in diesel passenger car emissions—increasing NO2/NOx ratio by conversion of NO into NO2 in catalysts and a disparity between the emission limit and the actual emissions in everyday d…
View article: Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children
Airborne Benzo[a]Pyrene may contribute to divergent Pheno-Endotypes in children Open
View article: High NO2 cOncentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate?
High NO2 cOncentrations Measured by Passive Samplers in Czech Cities: Unresolved Aftermath of Dieselgate? Open
This work examines the effects of two problematic trends in diesel passenger car emissions – increasing NO2/NOx ratio by conversion of NO into NO2 in catalysts and a disparity between the emission limit and the actual emissions in ev…
View article: The effects of age on<scp>DNA</scp>fragmentation, the condensation of chromatin and conventional semen parameters in healthy nonsmoking men exposed to traffic air pollution
The effects of age on<span>DNA</span>fragmentation, the condensation of chromatin and conventional semen parameters in healthy nonsmoking men exposed to traffic air pollution Open
Background Numerous studies have investigated age‐based declines in semen traits, but the impact of paternal age on semen parameter values remains inconclusive. Objectives The aim of this study was to detect an impact of age on semen quali…
View article: Running and Physical Activity in an Air-Polluted Environment: The Biomechanical and Musculoskeletal Protocol for a Prospective Cohort Study 4HAIE (Healthy Aging in Industrial Environment—Program 4)
Running and Physical Activity in an Air-Polluted Environment: The Biomechanical and Musculoskeletal Protocol for a Prospective Cohort Study 4HAIE (Healthy Aging in Industrial Environment—Program 4) Open
Far too little attention has been paid to health effects of air pollution and physical (in)activity on musculoskeletal health. The purpose of the Healthy aging in industrial environment study (4HAIE) is to investigate the potential impact …
View article: Regular running in an air-polluted environment: physiological and anthropometric protocol for a prospective cohort study (Healthy Aging in Industrial Environment Study – Program 4)
Regular running in an air-polluted environment: physiological and anthropometric protocol for a prospective cohort study (Healthy Aging in Industrial Environment Study – Program 4) Open
Introduction Ambient air pollution is a global environmental problem, which causes adverse health effects and premature deaths worldwide. Although regular exercise and physical activity have evident health benefits, the influence of long-t…
View article: The Impact of Cesarean and Vaginal Delivery on Results of Psychological Cognitive Test in 5 Year Old Children
The Impact of Cesarean and Vaginal Delivery on Results of Psychological Cognitive Test in 5 Year Old Children Open
Background and objectives: The impact of cesarean and vaginal delivery on cognitive development was analyzed in 5 year old children. Materials and Methods: Two cohorts of 5 year old children born in the years 2013 and 2014 in Karvina (Nort…
View article: Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children
Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children Open
Objectives: To analyze the impact of polycyclic aromatic hydrocarbons (PAHs) in ambient air at the time of delivery and five years of age on cognitive development in five year old children. Materials and Methods: Two cohorts of children bo…
View article: Impact of Air Pollution on the Health of the Population in Parts of the Czech Republic
Impact of Air Pollution on the Health of the Population in Parts of the Czech Republic Open
Thirty years ago, Northern Bohemia in the Czech Republic was one of the most air polluted areas in Europe. After political changes, the Czech government put forward a research program to determine if air pollution is really affecting human…
View article: The impact of air pollution on genes in relation to respiratory morbidity in children
The impact of air pollution on genes in relation to respiratory morbidity in children Open
View article: Comparison of polycyclic aromatic hydrocarbon metabolite concentrations in urine of mothers and their newborns
Comparison of polycyclic aromatic hydrocarbon metabolite concentrations in urine of mothers and their newborns Open