Radu Roşu
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View article: Multimodal Evaluation of Arrhythmogenic Substrate Predicts Atrial Fibrosis and Atrial Fibrillation Recurrence After Catheter Ablation
Multimodal Evaluation of Arrhythmogenic Substrate Predicts Atrial Fibrosis and Atrial Fibrillation Recurrence After Catheter Ablation Open
Background/Objectives: For many years, catheter ablation (CA) has been a cornerstone in atrial fibrillation (AF) rhythm control therapy; however, recurrence remains common. Multiple parameters have been proposed to quantify AF arrhythmogen…
View article: Impact of initial ablation parameters on pulmonary vein reconnection in redo high-power short-duration catheter ablation for atrial fibrillation
Impact of initial ablation parameters on pulmonary vein reconnection in redo high-power short-duration catheter ablation for atrial fibrillation Open
Introduction Pulmonary vein isolation (PVI) is the cornerstone for catheter ablation (CA) of atrial fibrillation (AF). Although acute electrical PVI is common during AF ablation, a key challenge in assessing long-term outcomes lays in the …
View article: The Impact of Trimethylamine N-Oxide on Atrial Fibrillation Presence in Patients with Cardiovascular Disease
The Impact of Trimethylamine N-Oxide on Atrial Fibrillation Presence in Patients with Cardiovascular Disease Open
Background: Atrial fibrillation is the most common human heart rhythm disorder, yet its underlying causes remain largely unknown. Trimethylamine N-oxide (TMAO), a by-product derived from the gut microbiota contributed by red meat, has been…
View article: Computed Tomography Confirms Increased Left Atrial Volume in Patients with Bayés Syndrome Referred for Catheter Ablation of Atrial Fibrillation
Computed Tomography Confirms Increased Left Atrial Volume in Patients with Bayés Syndrome Referred for Catheter Ablation of Atrial Fibrillation Open
Background: Bayés syndrome is a recently identified condition that is defined by the presence of an interatrial block on a surface electrocardiogram, in addition to atrial arrhythmias such as atrial fibrillation, tachycardia, or left atria…
View article: Recent Advances in Understanding the Molecular Mechanisms of SGLT2 Inhibitors in Atrial Remodeling
Recent Advances in Understanding the Molecular Mechanisms of SGLT2 Inhibitors in Atrial Remodeling Open
Atrial cardiomyopathy and remodeling play pivotal roles in the development of atrial fibrillation (AF) and heart failure (HF), involving complex changes in atrial structure and function. These changes facilitate the progression of AF and H…
View article: General Anesthesia Improves Efficiency of High-Power Short-Duration Catheter Ablation for Atrial Fibrillation: Comparison with Mild Conscious Sedation
General Anesthesia Improves Efficiency of High-Power Short-Duration Catheter Ablation for Atrial Fibrillation: Comparison with Mild Conscious Sedation Open
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia globally. High-power, short-duration radiofrequency (RF) catheter ablation (CA) for AF has recently emerged, reducing ablation times and enhancing patient tolerabil…
View article: Vitamin D Supplementation Improves Physical Performance in Athletes and Healthy Aging in Physically Active Adults
Vitamin D Supplementation Improves Physical Performance in Athletes and Healthy Aging in Physically Active Adults Open
Vitamin D deficiency is a significant global public health issue, even in regions with all year sun exposure. Currently, the scientific community has not yet reached a unanimous agreement regarding the optimum levels of vitamin D and the p…
View article: Optimizing cardiac rehabilitation by pacemaker reprogramming. Can we immediately improve the exercise capacity?
Optimizing cardiac rehabilitation by pacemaker reprogramming. Can we immediately improve the exercise capacity? Open
Background: Previous studies have demonstrated a direct correlation between pacemaker programming mode and exercise capacity on a long-term follow-up. In the present study we aimed to test whether reprogramming of the pacemaker can produce…
View article: The impact of chronic TMAO administration on liver oxidative stress, inflammation, and fibrosis
The impact of chronic TMAO administration on liver oxidative stress, inflammation, and fibrosis Open
Purpose TMAO, a gut microbiota derived byproduct, has been associated with various cardiometabolic diseases by promoting oxidative stress and inflammation. The liver is the main organ for TMAO production and chronic exposure to high doses …
View article: Apnea-Hypopnea Index an indicator of increased right cardiac preassures
Apnea-Hypopnea Index an indicator of increased right cardiac preassures Open
Funding Acknowledgements Type of funding sources: None. Introduction Obstructive sleep apnea (OSA) is a disorder frequently associated with clinical conditions and complications such as refractory hypertension, atrial fibrillation, nocturn…
View article: General anesthesia or mild conscious sedation? First comparison for high-power short-duration ablation for atrial fibrillation
General anesthesia or mild conscious sedation? First comparison for high-power short-duration ablation for atrial fibrillation Open
Funding Acknowledgements Type of funding sources: None. Background Atrial fibrillation (AF) represents the most common cardiac arrhythmia in adults worldwide. Catheter ablation (CA) of AF provides higher efficacy with comparable safety as …
View article: Galectin-3, Inflammation, and the Risk of Atrial High-Rate Episodes in Patients with Dual Chamber Pacemakers
Galectin-3, Inflammation, and the Risk of Atrial High-Rate Episodes in Patients with Dual Chamber Pacemakers Open
Atrial high-rate episodes (AHREs) are atrial tachyarrhythmias that are exclusively detected by cardiac implantable electronic devices (CIEDs) with an atrial lead. The objective of this study was to investigate the incidence and predictive …
View article: Predictors for the Development of Major Adverse Limb Events after Percutaneous Revascularization—Gender-Related Characteristics
Predictors for the Development of Major Adverse Limb Events after Percutaneous Revascularization—Gender-Related Characteristics Open
Background and Objectives: Revascularization has been proven to be superior to medication for symptom improvement in patients with peripheral arterial disease (PAD). There are well known gender differences in therapeutic strategies for PAD…
View article: Body size influences heart rate in children aged 6 to 18 years old
Body size influences heart rate in children aged 6 to 18 years old Open
Previous research established age-related normal limits for children’s heart rates (HRs). However, children of the same age can have significantly different HRs, depending on whether they are overweight or underweight, tall or short. Studi…
View article: Low Atrial Rhythm in a Large Cohort of Children from Transylvania, Romania
Low Atrial Rhythm in a Large Cohort of Children from Transylvania, Romania Open
Low atrial rhythm (LAR) is an ectopic rhythm originating in the lower part of the right or left atrium. Prior observational studies attempted to quantify the prevalence of low atrial rhythm in the pediatric population, but the observed pre…
View article: Atrial Fibrillation Ablation in a Patient with Cor Triatriatum Sinister and Left Common Pulmonary Vein: Impact of Left Atrium Anatomy on Ablation Approach
Atrial Fibrillation Ablation in a Patient with Cor Triatriatum Sinister and Left Common Pulmonary Vein: Impact of Left Atrium Anatomy on Ablation Approach Open
Atrial fibrillation is the most common presentation in adult patients with cor triatriatum sinister. The key to successful and safe catheter ablation in these patients is an accurate exploration and thorough understanding of the left atria…
View article: Anatomical-MRI Correlations in Adults and Children with Hypertrophic Cardiomyopathy
Anatomical-MRI Correlations in Adults and Children with Hypertrophic Cardiomyopathy Open
Hypertrophic Cardiomyopathy (HCM) is the most frequent hereditary cardiovascular disease and the leading cause of sudden cardiac death in young individuals. Advancements in CMR imaging have allowed for earlier identification and more accur…
View article: Left Atrial Volume Correlates with Mitral Annulus Size: An MDCT Study
Left Atrial Volume Correlates with Mitral Annulus Size: An MDCT Study Open
Aim: Although the association between left ventricular dilation and mitral annulus dilation is well understood, the potential variation in the size of the mitral annulus during dilation of the left atrium is currently unknown. In order to …
View article: Different response to vitamin D supplementation of PVCs from RVOT and non-outflow tract RV regions
Different response to vitamin D supplementation of PVCs from RVOT and non-outflow tract RV regions Open
Background Recent publications have shown that premature ventricular contractions (PVCs)_ from the right ventricular outflow tract (RVOT) have a good response to vitamin D supplementation in patients that have a vitamin D deficiency. Purpo…
View article: Formula to estimate left atrial volume using antero-posterior diameter in patients with catheter ablation of atrial fibrillation
Formula to estimate left atrial volume using antero-posterior diameter in patients with catheter ablation of atrial fibrillation Open
In patients undergoing atrial fibrillation (AF) ablation, an enlarged left atrium (LA) is a predictor of procedural failure as well as AF recurrence on long term. The most used method to assess LA size is echocardiography-measured diameter…
View article: The role of intracardiac echocardiography in reducing radiation exposure during atrial fibrillation ablation
The role of intracardiac echocardiography in reducing radiation exposure during atrial fibrillation ablation Open
Aims: Intracardiac echocardiography (ICE) is a relatively young technique used during complex electrophysiology proce-dures, such as atrial fibrillation (AF) ablation. The aim of this study was to assess whether the use of ICE modifies the…
View article: Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project
Validation of Normal P-Wave Parameters in a Large Unselected Pediatric Population of North-Western Romania: Results of the CARDIOPED Project Open
Aims. Reference values of the P-wave on 12 lead electrocardiograms are lacking for children and adolescents in Eastern Europe. Hence, the present study is aimed at determining the standard values of the P-wave in children and adolescents b…
View article: Atrial high-rate episodes: a comprehensive review
Atrial high-rate episodes: a comprehensive review Open
Cardiac electronic implantable devices (CIEDs) have the ability to monitor, store and interpret complex arrhythmias, which has generated a new arrhythmic entity: atrial high-rate episodes (AHRE). AHRE are atrial tachyarrhythmias, detected …
View article: Vitmamin D supplementation with Cardiac Rehabilitation reduces the number of RVOT Premature
Vitmamin D supplementation with Cardiac Rehabilitation reduces the number of RVOT Premature Open
Introduction. Vitamin D deficiency is a quite common pathology in European countries. Serum vitamin D levels are closely linked to physical fitness and lesser response to cardiac rehabilitation in various categories of patients with heart …
View article: Global work index by non-invasive pressure-strain loops: a novel parameter to assess left ventricular performance in the early stages of heart failure with preserved or mid-range ejection fraction after acute myocardial infarction
Global work index by non-invasive pressure-strain loops: a novel parameter to assess left ventricular performance in the early stages of heart failure with preserved or mid-range ejection fraction after acute myocardial infarction Open
Aim: To determine the relationship between myocardial work (MW) indices derived from non-invasive pressure-strain loops (PSL) and established parameters of left ventricular (LV) performance in patients with acute myocardial infarction (AMI…
View article: Catheter ablation of a latent accessory pathway under continuous infusion of adenosine
Catheter ablation of a latent accessory pathway under continuous infusion of adenosine Open
In case of a latent AP when ablation is difficult to perform because of absent conduction at the time of electrophysiological study, adenosine can be used in doses of 1.5 mg/kg over 5 minutes continuous infusion.
View article: I have an arrhythmia. Do I need Cardiac Rehabilitation ?
I have an arrhythmia. Do I need Cardiac Rehabilitation ? Open
This review shows that cardiac rehabilitation is not contraindicated in patients with arrhythmias; furthermore, it may be beneficial in reducing the number and severity of arrhythmia episodes. We will briefly describe the most common cardi…
View article: Transesophageal and intracardiac ultrasound in arrhythmogenic right ventricular dysplasia/cardiomyopathy
Transesophageal and intracardiac ultrasound in arrhythmogenic right ventricular dysplasia/cardiomyopathy Open
Rationale: Two-dimensional echocardiography (2D echo) is a major tool for the diagnosis of Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). However 2D echo can skip regional localized anomalies of the right ventricular w…
View article: What is the optimal duration of the TILT after administration of 0.4 mg nitroglycerin spray?
What is the optimal duration of the TILT after administration of 0.4 mg nitroglycerin spray? Open
Performing a head-up tilt test can be of great value for the diagnosis of vasovagal syncope. The European Society of Cardiology recommends a drug challenge phase duration of 15 to 20 minutes, with either Isoprenaline or Nitroglycerin admin…
View article: P338 The road to zero-fluoroscopy catheter ablation in recurrent paroxysmal atrial fibrillation using ICE: training, learning, getting closer
P338 The road to zero-fluoroscopy catheter ablation in recurrent paroxysmal atrial fibrillation using ICE: training, learning, getting closer Open
INTRODUCTION Catheter ablation is the treatment of choice for patients with recurrent paroxysmal atrial fibrillation (AF) in which antiarrhythmic drug therapy has failed to maintain sinus rhythm. Since its first introduction, intracardiac …