Rafael Rodrigues Lima
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View article: Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats
Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats Open
Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical perio…
View article: Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping Open
This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using t…
View article: Effects of Clarified Açaí Supplementation and Photobiomodulation on the Parotid Glands of Rats Submitted to Chemotherapy
Effects of Clarified Açaí Supplementation and Photobiomodulation on the Parotid Glands of Rats Submitted to Chemotherapy Open
Background The antineoplastic drugs used in anticancer treatment regimens can induce changes in normal tissues, including salivary glands. This study evaluated the effects of clarified açaí and photobiomodulation (PBM) on the oxidative bio…
View article: Insights into Parkinson’s Disease Pathology Focusing on Glial Response and Apoptosis in a Classic Rat Model of Dopaminergic Degeneration
Insights into Parkinson’s Disease Pathology Focusing on Glial Response and Apoptosis in a Classic Rat Model of Dopaminergic Degeneration Open
Background/Objectives: Parkinson’s disease (PD) is the second-most prevalent neurodegenerative disorder, characterized by the progressive loss of dopaminergic neurons in the Substantia Nigra pars compacta (SNpc). Experimental models that r…
View article: Performance of complementary therapies in controlling inflammatory signs, symptoms, and complications after lower third molar extraction: A bibliometric analysis of the top 100 most cited articles
Performance of complementary therapies in controlling inflammatory signs, symptoms, and complications after lower third molar extraction: A bibliometric analysis of the top 100 most cited articles Open
Objetivo: Realizar un análisis bibliométrico de los 100 artículos más citados sobre el uso de terapias complementarias para el control de los signos inflamatorios, síntomas y complicaciones tras la extracción de terceros molares inferiores…
View article: Effects of desensitizing and/or anti-erosive toothpastes combined with mouthrinses on enamel structure and dental pulp fibroblasts viability
Effects of desensitizing and/or anti-erosive toothpastes combined with mouthrinses on enamel structure and dental pulp fibroblasts viability Open
This study evaluated the chemical profile of toothpastes (TPs) and mouthrinses (MRs) and their effects on tooth enamel ultrastructure, and the viability of human dental pulp fibroblasts (hDPF). Four TPs and MRs containing different reminer…
View article: Is There Any Association Between Periodontitis and Prostatic Alterations? A Systematic Review
Is There Any Association Between Periodontitis and Prostatic Alterations? A Systematic Review Open
Background The prostate plays a crucial role in male reproduction but is susceptible to diseases such as prostate cancer. Periodontitis, as an inflammatory disease, has the potential to modulate systemic conditions. This systematic review …
View article: Neurodegeneration in Parkinson’s disease: are we looking at the right spot?
Neurodegeneration in Parkinson’s disease: are we looking at the right spot? Open
Parkinson’s disease (PD) is recognized as the fastest-growing neurodegenerative disorder, impacting millions of individuals worldwide. It is primarily characterized by cardinal motor symptoms, including bradykinesia (slowness of movement),…
View article: Jogos de corrida arcade e simuladores: diferenças na percepção do usuário e suas implicações no uso além do entretenimento
Jogos de corrida arcade e simuladores: diferenças na percepção do usuário e suas implicações no uso além do entretenimento Open
Este artigo examina as distinções entre jogos de corrida arcade e simuladores, categorias que surgiram a partir da popularização dos videogames nos anos 1970, especialmente em fliperamas.
View article: Investigation of the effects of benznidazole on the salivary glands: A biochemical, morphological, and functional approach
Investigation of the effects of benznidazole on the salivary glands: A biochemical, morphological, and functional approach Open
This study aimed to evaluate the possible biochemical effects of the administration of benznidazole on the parotid and submandibular salivary glands and saliva of rats, as well as on salivary components for the first time. Male Wistar rats…
View article: Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis
Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis Open
Aim This study aimed to investigate the effects of açai on bone and systemic damage caused by apical periodontitis (AP) in an animal model. Methodology In this experimental study, 32 male Wistar rats were randomly allocated into six groups…
View article: Evaluation of Yield, Chemical Composition and Antioxidant Capacity of the Essential Oil From Leaves and Fruits (Seed and Bark) of <i>Virola sebifera</i> Aubl. (Myristicaceae)
Evaluation of Yield, Chemical Composition and Antioxidant Capacity of the Essential Oil From Leaves and Fruits (Seed and Bark) of <i>Virola sebifera</i> Aubl. (Myristicaceae) Open
The essential oils (EOs) of Virola sebifera were obtained from leaves, seed fruits and husked fruits, collected during various times of the year (dry and rainy seasons) and extracted via hydrodistillation. The chemical composition of the E…
View article: Potential effects of induced focal ischemia in the motor cortex of rats undergoing experimental periodontitis
Potential effects of induced focal ischemia in the motor cortex of rats undergoing experimental periodontitis Open
Stroke is a severe medical condition resulting from an interruption in the blood supply to the brain, ultimately compromising tissue homeostasis. Currently, stroke stands as the second leading cause of death worldwide and the third leading…
View article: Chronic stress triggers impairments of the redox status of salivary glands associated with different histological responses in rats
Chronic stress triggers impairments of the redox status of salivary glands associated with different histological responses in rats Open
Stress occurs as a reaction to mental and emotional pressure, anxiety, or scarring. Chronic stress is defined as constant submission to these moments. It can affect several body systems, increase blood pressure, and weaken immunity, thereb…
View article: Performance of blood concentrates in controlling inflammatory signs and symptoms after lower third molar extractions: an overview
Performance of blood concentrates in controlling inflammatory signs and symptoms after lower third molar extractions: an overview Open
Purpose: To summarize the available evidence and answer the following question: What is the current knowledge on the performance of blood concentrates in handling sequelae after lower third molar extractions with the evidence available in …
View article: IMPACTO DA INTELIGÊNCIA ARTIFICIAL NA SEGURANÇA DA INFORMAÇÃO NO SETOR DA SAÚDE
IMPACTO DA INTELIGÊNCIA ARTIFICIAL NA SEGURANÇA DA INFORMAÇÃO NO SETOR DA SAÚDE Open
View article: Blood concentrates for controlling postoperative complications from third molar surgeries: a scoping review
Blood concentrates for controlling postoperative complications from third molar surgeries: a scoping review Open
Purpose: To map the literature on blood concentrates for managing postoperative sequelae after third molar extraction through a scoping review. Methods: MedLine, Latin American and Caribbean Health Sciences Literature, Scientific Electroni…
View article: High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats
High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats Open
View article: Minocycline reduces alveolar bone loss and bone damage in Wistar rats with experimental periodontitis
Minocycline reduces alveolar bone loss and bone damage in Wistar rats with experimental periodontitis Open
This study aimed to investigate the impact of minocycline on the alveolar bone in experimental periodontitis in rats. Thirty Wistar rats were randomly assigned to three groups: control without periodontitis; experimental periodontitis indu…
View article: Cost-effectiveness of home care compared to hospital care in patients with chronic obstructive pulmonary disease (COPD): a systematic review
Cost-effectiveness of home care compared to hospital care in patients with chronic obstructive pulmonary disease (COPD): a systematic review Open
Background To compare, through a systematic literature review, the cost-effectiveness ratio of home care compared to hospital care for following up patients with chronic obstructive pulmonary disease (COPD). Methods This review was registe…
View article: Vogt Konayagi Harada syndrome in an 8-year-old patient
Vogt Konayagi Harada syndrome in an 8-year-old patient Open
View article: Twenty-first century knowledge mapping on oral diseases and physical activity/exercise, trends, gaps, and future perspectives: a bibliometric review
Twenty-first century knowledge mapping on oral diseases and physical activity/exercise, trends, gaps, and future perspectives: a bibliometric review Open
Maintenance and improvement of an individual's overall well-being require a multidisciplinary approach that encompasses everything from oral health care to regular physical exercise. The notion that poor oral health can influence general h…
View article: Analysis of Chemical Composition, Antioxidant Activity, and Toxicity of Essential Oil from Virola sebifera Aubl (Myristicaceae)
Analysis of Chemical Composition, Antioxidant Activity, and Toxicity of Essential Oil from Virola sebifera Aubl (Myristicaceae) Open
Volatile oils or essential oils (EOs) were extracted from three V. sebifera samples (labeled as A, B, and C) in September 2018 and February 2019; the extraction process involved hydrodistillation of the leaves. The chemical compositions of…
View article: Linalool-rich rosewood essential oil (Aniba rosaeodora Ducke) mitigates emotional and neurochemical impairments induced by ethanol binge-like exposure during adolescence in female rats
Linalool-rich rosewood essential oil (Aniba rosaeodora Ducke) mitigates emotional and neurochemical impairments induced by ethanol binge-like exposure during adolescence in female rats Open
Linalool-rich Rosewood oil (Aniba rosaeodora Ducke) is a natural compound widely used in perfumery industry. Evidence suggests that linalool exerts antidepressant and anxiolytic effects. Conversely, ethanol binge drinking (i.e., intermitte…
View article: Physical training minimizes immunological dysfunction, oxidative stress and tissue destruction on experimental periodontitis in rats
Physical training minimizes immunological dysfunction, oxidative stress and tissue destruction on experimental periodontitis in rats Open
The objective of this study is to investigate the effects of a moderate intensity physical training protocol, on alveolar bone morphology of rats submitted to ligature-induced periodontitis. Twenty-eight male Wistar rats were divided into …
View article: Is there any association between the presence of biomarkers and apical periodontitis? A systematic review
Is there any association between the presence of biomarkers and apical periodontitis? A systematic review Open
This systematic review aimed to verify whether there is evidence of an association between apical periodontitis and the presence of systemic biomarkers. This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-An…
View article: Açai (Euterpe oleracea Mart.) supplementation promotes histological and ultrastructural changes in rats' alveolar bone
Açai (Euterpe oleracea Mart.) supplementation promotes histological and ultrastructural changes in rats' alveolar bone Open
View article: Physical training mitigates alveolar bone and blood enzymatic antioxidants defense impairment induced by binge ethanol consumption in rats
Physical training mitigates alveolar bone and blood enzymatic antioxidants defense impairment induced by binge ethanol consumption in rats Open
We aimed to investigate the effectiveness of physical training as a protective strategy to mitigate alveolar bone damage and blood antioxidant defense caused by ethanol (EtOH) consumption in a binge-drinking pattern. Male Wistar rats aged …
View article: Is there any association between fluoride exposure and thyroid function modulation? A systematic review
Is there any association between fluoride exposure and thyroid function modulation? A systematic review Open
Numerous pre-clinical and observational studies have explored the potential effects of fluoride (F) at varying concentrations on diverse systems and organs. While some have assessed the endocrinological conditions of children and adults, a…
View article: Physical training attenuates systemic cytokine response and tissue damage triggered by apical periodontitis
Physical training attenuates systemic cytokine response and tissue damage triggered by apical periodontitis Open
Apical periodontitis (AP) is a condition characterized by inflammatory and infectious components in the tooth canal. AP affects periradicular tissues and has systemic repercussions. Physical exercise is a structured activity that requires …