Rafael Piñol
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View article: Enhancement of Tumor Cell Immunogenicity and Antitumor Properties Derived from Platinum-Conjugated Iron Nanoparticles
Enhancement of Tumor Cell Immunogenicity and Antitumor Properties Derived from Platinum-Conjugated Iron Nanoparticles Open
From chemistry design to clinical application, several approaches have been developed to overcome platinum drawbacks in antitumoral therapies. An in-depth understanding of intracellular signaling may hold the key to the relationship of bot…
View article: Local Temperature Increments and Induced Cell Death in Intracellular Magnetic Hyperthermia
Local Temperature Increments and Induced Cell Death in Intracellular Magnetic Hyperthermia Open
The generation of temperature gradients on nanoparticles heated externally by a magnetic field is crucially important in magnetic hyperthermia therapy. But the intrinsic low heating power of magnetic nanoparticles, at the conditions allowe…
View article: The Anti-Obesity Potential of Superparamagnetic Iron Oxide Nanoparticles against High-Fat Diet-Induced Obesity in Rats: Possible Involvement of Mitochondrial Biogenesis in the Adipose Tissues
The Anti-Obesity Potential of Superparamagnetic Iron Oxide Nanoparticles against High-Fat Diet-Induced Obesity in Rats: Possible Involvement of Mitochondrial Biogenesis in the Adipose Tissues Open
Background: Obesity is a pandemic disease that is rapidly growing into a serious health problem and has economic impact on healthcare systems. This bleak image has elicited creative responses, and nanotechnology is a promising approach in …
View article: Efficient Brownian oscillators and nanoheaters based on gallium-doped ε-Fe<sub>2</sub>O<sub>3</sub>
Efficient Brownian oscillators and nanoheaters based on gallium-doped ε-Fe<sub>2</sub>O<sub>3</sub> Open
ε-GaxFe2−xO3 nanoparticles with huge coercivity and moderate magnetization can be useful in both mechanical and heating wireless magnetic actuation due to their low tendency to agglomerate.
View article: Magnetic hyperthermia with e-Fe2O3 nanoparticles
Magnetic hyperthermia with e-Fe2O3 nanoparticles Open
These data correspond to the figures in the paper: Gu Y. et al. RSC Adv., 2020, 10, 28786–28797. doi:10.1039/d0ra04361c.
View article: Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model
Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model Open
The data correspond to figures in the paper by Ali, L.M.A. et al. Life Sciences 245 (2020) 117361. doi:10.1016/j.lfs.2020.117361.
View article: Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model
Effect of superparamagnetic iron oxide nanoparticles on glucose homeostasis on type 2 diabetes experimental model Open
The data correspond to figures in the paper by Ali, L.M.A. et al. Life Sciences 245 (2020) 117361. doi:10.1016/j.lfs.2020.117361.
View article: Magnetic hyperthermia with e-Fe2O3 nanoparticles
Magnetic hyperthermia with e-Fe2O3 nanoparticles Open
These data correspond to the figures in the paper: Gu Y. et al. RSC Adv., 2020, 10, 28786–28797. doi:10.1039/d0ra04361c.
View article: Real-time intracellular temperature imaging using lanthanide-bearing polymeric micelles
Real-time intracellular temperature imaging using lanthanide-bearing polymeric micelles Open
Measurement of thermogenesis in individual cells is a remarkable challenge due to the complexity of the biochemical environment (such as pH and ionic strength) and to the rapid and yet not well-understood heat transfer mechanisms throughou…
View article: Real-Time Intracellular Temperature Imaging Using Lanthanide-Bearing Polymeric Micelles
Real-Time Intracellular Temperature Imaging Using Lanthanide-Bearing Polymeric Micelles Open
Measurement of thermogenesis in individual cells is a remarkable challenge due to the complexity of the biochemical environment (such as pH and ionic strength) and to the rapid and yet not well-understood heat transfer mechanisms throughou…
View article: Molecular Logic Devices: Lanthanide Luminescence to Mimic Molecular Logic and Computing through Physical Inputs (Advanced Optical Materials 12/2020)
Molecular Logic Devices: Lanthanide Luminescence to Mimic Molecular Logic and Computing through Physical Inputs (Advanced Optical Materials 12/2020) Open
Innovative monolithic silicon-based structures incorporating luminescent lanthanide-based complexes for performing logical functions are reported by Carlos D. S. Brites, Luís D. Carlos and co-workers in article number 2000312. This is the …
View article: Lanthanide Luminescence to Mimic Molecular Logic and Computing through Physical Inputs
Lanthanide Luminescence to Mimic Molecular Logic and Computing through Physical Inputs Open
The remarkable advances in molecular logic reported in the last decade demonstrate the potential of luminescent molecules for logical operations, a paradigm‐changing concerning silicon‐based electronics. Trivalent lanthanide (Ln 3+ ) ions,…
View article: Magnetic hyperthermia with ε-Fe<sub>2</sub>O<sub>3</sub> nanoparticles
Magnetic hyperthermia with ε-Fe<sub>2</sub>O<sub>3</sub> nanoparticles Open
ε-Fe2O3 is a magnetic iron(iii) oxide with a giant coercivity. Its potential in hyperthermia applications has been evaluated in comparison with γ-Fe2O3 over a wide range of field frequencies and amplitudes.
View article: MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles
MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles Open
Dataset accompanying figures published in the publication DOI: 10.3390/bios8040127
View article: MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles
MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles Open
Dataset accompanying figures published in the publication DOI: 10.3390/bios8040127
View article: MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles
MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles Open
Dataset accompanying figures published in the publication DOI: 10.3390/bios8040127
View article: Ratiometric thermometry using lanthanides complexes for biomedical applications
Ratiometric thermometry using lanthanides complexes for biomedical applications Open
Resumen del trabajo presentado a la 2nd Spanish Conference on Biomedical Applications of Nanomaterials (SBAN), celebrada en Madrid del 6 al 7 de junio de 2019.
View article: MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles
MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles Open
Medical imaging is an active field of research that fosters the necessity for novel multimodal imaging probes. In this line, nanoparticle-based contrast agents are of special interest, since those can host functional entities either within…
View article: MRI Study of the Influence of Surface Coating Aging on the <em>In Vivo</em> Biodistribution of Iron Oxide Nanoparticles
MRI Study of the Influence of Surface Coating Aging on the <em>In Vivo</em> Biodistribution of Iron Oxide Nanoparticles Open
Medical imaging is an active field of research that fosters the necessity for novel multimodal imaging probes. In this line, nanoparticle-based contrast agents are of special interest, since those can host functional entities either within…
View article: PEG-copolymer-coated iron oxide nanoparticles that avoid the reticuloendothelial system and act as kidney MRI contrast agents
PEG-copolymer-coated iron oxide nanoparticles that avoid the reticuloendothelial system and act as kidney MRI contrast agents Open
PEG coated magnetic nanocarriers avoid the reticuloendothelial system, and show an MRI contrast in the kidneys. The results are supported by SPECT, gamma-counting, MRI and TEM histology.
View article: Polymer-Coated Superparamagnetic Iron Oxide Nanoparticles as T <sub>2</sub> Contrast Agent for MRI and their Uptake in Liver
Polymer-Coated Superparamagnetic Iron Oxide Nanoparticles as T <sub>2</sub> Contrast Agent for MRI and their Uptake in Liver Open
Our bioferrofluids are powerful diagnostic tool without any observed toxicity over a period of 60 days post-injection.
View article: Tuning Properties of Iron Oxide Nanoparticles in Aqueous Synthesis without Ligands to Improve MRI Relaxivity and SAR
Tuning Properties of Iron Oxide Nanoparticles in Aqueous Synthesis without Ligands to Improve MRI Relaxivity and SAR Open
Aqueous synthesis without ligands of iron oxide nanoparticles (IONPs) with exceptional properties still remains an open issue, because of the challenge to control simultaneously numerous properties of the IONPs in these rigorous settings. …
View article: Controlling structural and magnetic properties of IONPs by aqueous synthesis for improved hyperthermia
Controlling structural and magnetic properties of IONPs by aqueous synthesis for improved hyperthermia Open
Introducing a hydrothermal step after coprecipitation leads to iron oxide nanoparticles with higher vacancy ordering, saturation magnetization and specific absorption rate.
View article: High time resolution thermometry on a magnetic nanoheater. A new tool for hyperthermia
High time resolution thermometry on a magnetic nanoheater. A new tool for hyperthermia Open
Resumen del trabajo presentado a la NanoSpain Conference, celbrado en Logroño del 15 al 18 de marzo de 2016.
View article: M4 -Multifunctional Molecular Magnetic Materials
M4 -Multifunctional Molecular Magnetic Materials Open
Trabajo presentado al I Congreso del Instituto de Ciencia de Materiales de Aragón: “Materiales para los retos de la sociedad", celebrado en Benasque (Huesca) del 1 al 3 de febrero de 2016.
View article: Implementing Thermometry on Silicon Surfaces Functionalized by Lanthanide‐Doped Self‐Assembled Polymer Monolayers
Implementing Thermometry on Silicon Surfaces Functionalized by Lanthanide‐Doped Self‐Assembled Polymer Monolayers Open
The thermal gradients generated at submicrometer scale by the millions of transistors contained in integrated circuits are becoming the key limiting factor for device integration in micro‐ and nanoelectronics. Noncontact thermometric techn…