Rafael Zotz
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View article: In vivo treatment with M8, a highly diluted tinctures complex, reduced the malignancy of a mouse melanoma model
In vivo treatment with M8, a highly diluted tinctures complex, reduced the malignancy of a mouse melanoma model Open
Background: Cancer is a class of disease responsible for 13% of death cause worldwide. Among all types of cancers, one of the most aggressive and with the highest death rate is melanoma. It is highly metastatic and current treatments with …
View article: Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals?
Refinement as ethics principle in animal research: Is it necessary to standardize the Environmental enrichment in laboratory animals? Open
The Environmental enrichment technique, although scientifically recognized for raising the level of animal welfare, has led to the questioning of its influence on the results of experimental research. Thus, the goal is to promote reflectio…
View article: Morphometric and Molecular Muscle Remodeling after Passive Stretching in Elderly Female Rats
Morphometric and Molecular Muscle Remodeling after Passive Stretching in Elderly Female Rats Open
Three sessions of static stretching reduced the gene expression level of TGF-β1, which, owing to its anti-fibrotic role, might contribute to the remodeling of the intramuscular connective tissue of the aging muscle. In addition, immunostai…
View article: The development of a mechanical device to stretch skeletal muscle of young and old rats
The development of a mechanical device to stretch skeletal muscle of young and old rats Open
The device presented in this study is able to monitor the force necessary to stretch hindlimb rat muscles. Aged rats required less force than young rats to stretch the soleus muscle, and there was no difference regarding the tibio-tarsal a…