Rafaela Machado Filardi
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View article: Topical Lidocaine During Airway Manipulation in Pediatric Anesthesia: A Systematic Review and Meta‐Analysis
Topical Lidocaine During Airway Manipulation in Pediatric Anesthesia: A Systematic Review and Meta‐Analysis Open
Introduction Lidocaine is widely used in pediatric anesthesia for airway topicalization to modulate undesirable airway and circulatory reflexes, yet its effectiveness remains unclear. Therefore, we aimed to perform a meta‐analysis evaluati…
View article: Topical Lidocaine During Airway Manipulation in Pediatric Anesthesia: A Systematic Review and Meta‐Analysis
Topical Lidocaine During Airway Manipulation in Pediatric Anesthesia: A Systematic Review and Meta‐Analysis Open
Introduction Lidocaine is widely used in pediatric anesthesia for airway topicalization to modulate undesirable airway and circulatory reflexes, yet its effectiveness remains unclear. Therefore, we aimed to perform a meta‐analysis evaluati…
View article: The Silent Cognitive Burden of Chronic Pain: Protocol for an AI-Enhanced Living Dose–Response Bayesian Meta-Analysis
The Silent Cognitive Burden of Chronic Pain: Protocol for an AI-Enhanced Living Dose–Response Bayesian Meta-Analysis Open
Background: Chronic pain affects nearly one in five adults worldwide and is increasingly recognized not only as a disease but as a potential risk factor for neurocognitive decline and dementia. While some evidence supports this association…
View article: The Role of Maladaptive Plasticity in Modulating Pain Pressure Threshold Post-Spinal Cord Injury
The Role of Maladaptive Plasticity in Modulating Pain Pressure Threshold Post-Spinal Cord Injury Open
Background: Spinal cord injury (SCI) frequently leads to pain, leading to significant disability. Pain sensitization, a key feature of SCI, is commonly assessed via quantitative sensory testing like the Pressure Pain Threshold (PPT), thoug…
View article: The Link between Endogenous Pain Modulation Changes and Clinical Improvement in Fibromyalgia Syndrome: A Meta-Regression Analysis
The Link between Endogenous Pain Modulation Changes and Clinical Improvement in Fibromyalgia Syndrome: A Meta-Regression Analysis Open
Conditioned pain modulation (CPM) and temporal summation (TS) tests can measure the ability to inhibit pain in fibromyalgia syndrome (FMS) patients and its level of pain sensitization, respectively. However, their clinical validity is stil…