Rafik Abdelsayed
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View article: Obesity Promotes Renal Inflammation and Fibrosis Independent of Sex in SS Leptin Receptor Mutant (SSLepR) Rats
Obesity Promotes Renal Inflammation and Fibrosis Independent of Sex in SS Leptin Receptor Mutant (SSLepR) Rats Open
Background: Obesity is a major contributor to chronic kidney disease (CKD) through mechanisms involving inflammation and metabolic dysregulation. Premenopausal female rats are known to be protected from cardiovascular disorders vs. age mat…
View article: Salivary Gland Sarcoidosis: Systematic Review of Case Reports and Case Series
Salivary Gland Sarcoidosis: Systematic Review of Case Reports and Case Series Open
Background: Salivary gland sarcoidosis is a rare manifestation of systemic sarcoidosis that poses a challenge in terms of its diagnosis due to its similarities to disorders such as Sjögren’s syndrome, other granulomatous diseases, and infe…
View article: EP17.05 CAPECITABINE-INDUCED ACUTE NEUROTOXICITY IN CHARCOT-MARIE-TOOTH DISEASE: CASE REPORT AND MINI-SYSTEMATIC REVIEW
EP17.05 CAPECITABINE-INDUCED ACUTE NEUROTOXICITY IN CHARCOT-MARIE-TOOTH DISEASE: CASE REPORT AND MINI-SYSTEMATIC REVIEW Open
BACKGROUND Charcot-Marie-Tooth disease (CMT) is a hereditary neuropathy with variable severity, commonly affecting motor and sensory peripheral nerves. In oncology, chemotherapy-induced peripheral neuropathy (CIPN) presents a significant c…
View article: Expression profiles of SGK-1 and α-ENaC in minor salivary glands of subjects with xerostomia
Expression profiles of SGK-1 and α-ENaC in minor salivary glands of subjects with xerostomia Open
Introduction Epithelial sodium channel (ENaC) is a major conduit for sodium transport across the cell membrane, and its activity is regulated by multiple factors/mechanisms, including the serum and glucocorticoid-regulated kinase-1 (SGK-1)…
View article: Nonscrapable yeast: A case of chronic hyperplastic candidiasis following secukinumab therapy
Nonscrapable yeast: A case of chronic hyperplastic candidiasis following secukinumab therapy Open
View article: Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SSLepR Mutant Rats?
Does Sex Matter in Obesity-Induced Periodontal Inflammation in the SSLepR Mutant Rats? Open
Introduction: The incidence of obesity has dramatically increased worldwide. Obesity has been shown to exacerbate the progression of periodontal disease. Studies suggest a sex difference in periodontitis, whereby males are more sensitive t…
View article: Benign Myoepithelial Neoplasms of Salivary Glands: Clinicopathologic Profile and Literature Review
Benign Myoepithelial Neoplasms of Salivary Glands: Clinicopathologic Profile and Literature Review Open
OBJECTIVES: This article aims to expand the literature on myoepitheliomas by describing several cases with an emphasis on histological presentation, clinical appearance, and demographics. To the best of our knowledge, this article is the l…
View article: Causes of Oral Granulomatous Disorders: An Update and Narrative Review of the Literature
Causes of Oral Granulomatous Disorders: An Update and Narrative Review of the Literature Open
View article: Acknowledgement to Reviewers 2023
Acknowledgement to Reviewers 2023 Open
View article: Expression profiles of glucocorticoid-inducible proteins in human papilloma virus-related oropharyngeal squamous cell carcinoma
Expression profiles of glucocorticoid-inducible proteins in human papilloma virus-related oropharyngeal squamous cell carcinoma Open
Introduction Human papillomavirus virus-related oropharyngeal squamous cell carcinoma (HPV-OPSCC) comprises a significant portion of head and neck cancers. Several glucocorticoid-inducible proteins play important roles in pathogenesis of s…
View article: Numb chin syndrome as initial symptom of T-cell acute lymphoblastic leukemia in a 14-year-old female: A case report
Numb chin syndrome as initial symptom of T-cell acute lymphoblastic leukemia in a 14-year-old female: A case report Open
View article: Expression Profiles of GILZ and Annexin A1 in Human Oral Candidiasis and Lichen Planus
Expression Profiles of GILZ and Annexin A1 in Human Oral Candidiasis and Lichen Planus Open
Adrenal glands are the major source of glucocorticoids, but recent studies indicate tissue-specific production of cortisol, including that in the oral mucosa. Both endogenous and exogenous glucocorticoids regulate the production of several…
View article: Clear Cell Odontogenic Carcinoma: A Series of Three Cases
Clear Cell Odontogenic Carcinoma: A Series of Three Cases Open
Background: Clear cell odontogenic carcinoma (CCOC) is a rare malignant odontogenic epithelial neoplasm of the jaws. It is composed of irregular nests of clear to faintly eosinophilic cells resembling clear cell rests of primitive dental l…
View article: Surgical Ciliated Cyst of the Maxilla: A Case-Series of Three Cases
Surgical Ciliated Cyst of the Maxilla: A Case-Series of Three Cases Open
The surgical ciliated cyst is an iatrogenic lesion occurring after surgeries in which the Schneiderian membrane has been exposed, such as in orthognathic surgery or maxillary sinus procedures. This lesion has been infrequently documented i…
View article: A Locally Aggressive Ameloblastic Fibro-Odontoma: A Case Report and Literature Review
A Locally Aggressive Ameloblastic Fibro-Odontoma: A Case Report and Literature Review Open
View article: Expression Profiles of GILZ and SGK-1 in Potentially Malignant and Malignant Human Oral Lesions
Expression Profiles of GILZ and SGK-1 in Potentially Malignant and Malignant Human Oral Lesions Open
Glucocorticoid-induced leucine zipper and serum-glucocorticoid-regulated kinase-1 (SGK-1) are major glucocorticoid-inducible proteins. Recent studies indicate the local production of cortisol in oral mucosa, which can impact the tissue gen…
View article: Salvianolic Acid B Slows the Progression of Breast Cancer Cell Growth via Enhancement of Apoptosis and Reduction of Oxidative Stress, Inflammation, and Angiogenesis
Salvianolic Acid B Slows the Progression of Breast Cancer Cell Growth via Enhancement of Apoptosis and Reduction of Oxidative Stress, Inflammation, and Angiogenesis Open
Breast cancer is the current leading cause of cancer death in females worldwide. Although current chemotherapeutic drugs effectively reduce the progression of breast cancer, most of these drugs have many unwanted side effects. Salvianolic …
View article: A dual role of 12/15-lipoxygenase in LPS-induced acute renal inflammation and injury
A dual role of 12/15-lipoxygenase in LPS-induced acute renal inflammation and injury Open
View article: Increased Innate Lymphoid Cells in Periodontal Tissue of the Murine Model of Periodontitis: The Role of AMP-Activated Protein Kinase and Relevance for the Human Condition
Increased Innate Lymphoid Cells in Periodontal Tissue of the Murine Model of Periodontitis: The Role of AMP-Activated Protein Kinase and Relevance for the Human Condition Open
Innate lymphoid cells (ILCs) are master regulators of immune and inflammatory responses, but their own regulatory mechanisms and functional roles of their subtypes (i.e., ILC1s-ILC3s) remain largely unresolved. Interestingly, AMP-activated…
View article: Kaposi sarcoma presenting as “diffuse gingival enlargement”: Report of three cases
Kaposi sarcoma presenting as “diffuse gingival enlargement”: Report of three cases Open
Kaposi sarcoma (KS) is an angio-proliferative disorder, associated with human herpes virus-8 (HHV-8) infection. Its occurrence may be favored by human immunodeficiency virus (HIV) infection and iatrogenic immunosuppression. In this article…
View article: The status of glucocorticoid-induced leucine zipper protein in the salivary glands in Sjögren’s syndrome: predictive and prognostic potentials
The status of glucocorticoid-induced leucine zipper protein in the salivary glands in Sjögren’s syndrome: predictive and prognostic potentials Open
Complementing our demonstration of Del-1/IL-17 imbalance in salivary glands in SS, the present study has established the relevance and significance of GILZ as a novel predictive and prognostic molecular fingerprint for SS. Thus, assessment…