Raghu Pullakhandam
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View article: Impact evaluation of a population-based ‘Screen and Treat for Anaemia Reduction (STAR)’ strategy: a cluster randomised trial in rural Telangana, India
Impact evaluation of a population-based ‘Screen and Treat for Anaemia Reduction (STAR)’ strategy: a cluster randomised trial in rural Telangana, India Open
Introduction Population level screen and treat approach for anaemia reduction could be beneficial but its feasibility and impact remains to be tested. Methods This cluster randomised trial in rural Telangana included 14 clusters randomised…
View article: PRAYAS: Cohort profile for Pooled Research and Analysis for Yielding Anemia-free Solutions in India
PRAYAS: Cohort profile for Pooled Research and Analysis for Yielding Anemia-free Solutions in India Open
Purpose This cohort would aim to estimate the prevalence of anemia among children under 18 years, non-pregnant and non-lactating (NPNL) women, and pregnant women (by trimester), with further stratification by age group, year, and region of…
View article: Predictors of Sleep Quality Among Emerging Adults in India: Exploring the Role of FoMO, Nomophobia and Evening Chronotype
Predictors of Sleep Quality Among Emerging Adults in India: Exploring the Role of FoMO, Nomophobia and Evening Chronotype Open
Background The increasing integration of mobile technology into daily life has raised concerns about its effects on sleep quality and mental health, particularly among emerging adults. The interplay between evening chronotype, nomophobia (…
View article: Screening for anemia using multi-modal machine learning models on smartphones: protocol for a comparative accuracy study in rural India
Screening for anemia using multi-modal machine learning models on smartphones: protocol for a comparative accuracy study in rural India Open
Introduction Anemia, or low blood hemoglobin (Hb), affects one third of the world population, and is particularly prevalent in women and children in lower resource settings. However, screening for anemia is limited by the availability of a…
View article: Recommendations for India-specific multiple micronutrient supplement through expert consultation
Recommendations for India-specific multiple micronutrient supplement through expert consultation Open
Background & objectives Reducing maternal anaemia and enhancing feto-maternal health to achieve desired birth outcomes is a major health concern in India. Micronutrient deficiencies during pregnancy may impact fetal growth and neonatal out…
View article: Eggs for Improving Nutrition, cognitive development and reducing linear growth retardation among Infants and young Children (ENRICH): protocol of an egg supplementation trial among children aged 9–18 months in Hyderabad, India
Eggs for Improving Nutrition, cognitive development and reducing linear growth retardation among Infants and young Children (ENRICH): protocol of an egg supplementation trial among children aged 9–18 months in Hyderabad, India Open
Introduction Evidence on the impact of nutrient-rich animal source foods such as eggs for improving child growth and cognition is inconsistent. This study aims to examine the impact of an egg intervention in children, along with behaviour …
View article: Anthropometric, biochemical, dietary, morbidity and well-being assessments in women and children in Indonesia, India and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper
Anthropometric, biochemical, dietary, morbidity and well-being assessments in women and children in Indonesia, India and Senegal: a UKRI GCRF Action Against Stunting Hub protocol paper Open
Introduction Child stunting has a complex aetiology, especially in the first 1000 days of life. Nutrition interventions alone have not produced expected impacts in reducing/preventing child stunting, indicating the importance of understand…
View article: Prevalence of Vitamin B12 and Folate Deficiencies in Indian Children and Adolescents
Prevalence of Vitamin B12 and Folate Deficiencies in Indian Children and Adolescents Open
Deficiencies of vitamin B12 (B12) and folate (FA) are of particular interest due to their pleiotropic role in 1-carbon metabolism. In addition to adverse birth outcomes, deficiencies of B12 and FA, or an imbalance in FA/B12 status, are lin…
View article: Prevalence of Vitamin B<sub>12</sub> and Folate Deficiencies in Indian Children and Adolescents
Prevalence of Vitamin B<sub>12</sub> and Folate Deficiencies in Indian Children and Adolescents Open
Deficiencies of vitamin B12 (B12) and folate (FA) are of particular interest due to their pleiotropic role in 1-carbon metabolism. In addition to adverse birth outcomes, deficiencies of B12 and FA, or an imbalance in FA/B12 status, are lin…
View article: Quercetin Inhibits Hephaestin Expression and Iron Transport in Intestinal Cells: Possible Role of PI3K Pathway
Quercetin Inhibits Hephaestin Expression and Iron Transport in Intestinal Cells: Possible Role of PI3K Pathway Open
Previous studies demonstrated that quercetin, a polyphenolic compound, inhibits the transport of iron by down-regulation of ferroportin (FPN1), an iron export protein. We have previously demonstrated that activation of the PI3K signaling p…
View article: Haemoglobin diagnostic cut-offs for anaemia in Indian women of reproductive age
Haemoglobin diagnostic cut-offs for anaemia in Indian women of reproductive age Open
Background The persistent high prevalence of anaemia among Indian women of reproductive age (WRA) despite aggressive long-term iron supplementation, could be related to over-diagnosis from an inappropriately high haemoglobin (Hb) diagnosti…
View article: Nutritional requirements for the elderly in India: A status paper
Nutritional requirements for the elderly in India: A status paper Open
Advances in the medical field and healthcare sector during the last few decades have resulted in increased longevity. Increased lifespans have in turn led to a rapid global rise of the elderly population. However, ensuring the health and q…
View article: ‘Screen and Treat for Anaemia Reduction (STAR)’ strategy: study protocol of a cluster randomised trial in rural Telangana, India
‘Screen and Treat for Anaemia Reduction (STAR)’ strategy: study protocol of a cluster randomised trial in rural Telangana, India Open
Introduction Current anaemia control programme focusing on prophylactic iron supplementation and facility-based screening with haemoglobin estimation is inadequate to reduce the high prevalence of anaemia in India. This study aims to exami…
View article: SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021
SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021 Open
Over half the city's population was infected within a year of onset of the pandemic. However, ∼ 46% of people remained susceptible, contributing to subsequent waves of infection.
View article: Chronic Effects of Maternal Low-Protein and Low-Quality Protein Diets on Body Composition, Glucose-Homeostasis and Metabolic Factors, Followed by Reversible Changes upon Rehabilitation in Adult Rat Offspring
Chronic Effects of Maternal Low-Protein and Low-Quality Protein Diets on Body Composition, Glucose-Homeostasis and Metabolic Factors, Followed by Reversible Changes upon Rehabilitation in Adult Rat Offspring Open
Several studies suggest that the maternal protein content and source can affect the offspring’s health. However, the chronic impact of maternal quality and quantity protein restriction, and reversible changes upon rehabilitation, if any, i…
View article: Relative Efficacy of Vitamin D2 and Vitamin D3 in Improving Vitamin D Status: Systematic Review and Meta-Analysis
Relative Efficacy of Vitamin D2 and Vitamin D3 in Improving Vitamin D Status: Systematic Review and Meta-Analysis Open
Background: Widespread prevalence of vitamin D deficiency has been documented globally. Commonly used interventions to address this deficiency include supplementation and/or fortification with either ergocalciferol (vitamin D2) or cholecal…
View article: SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021
SARS-CoV-2 seroprevalence in the city of Hyderabad, India in early 2021 Open
Background COVID-19 emerged as a global pandemic in 2020, rapidly spreading to most parts of the world. The proportion of infected individuals in a population can be reliably estimated via sero-surveillance, making it a valuable tool for p…
View article: The Effects of a Single Freeze-Thaw Cycle on Concentrations of Nutritional, Noncommunicable Disease, and Inflammatory Biomarkers in Serum Samples
The Effects of a Single Freeze-Thaw Cycle on Concentrations of Nutritional, Noncommunicable Disease, and Inflammatory Biomarkers in Serum Samples Open
Background The stability of biological samples is vital for reliable measurements of biomarkers in large-scale survey settings, which may be affected by freeze-thaw procedures. We examined the effect of a single freeze-thaw cycle on 13 nut…
View article: High dietary micronutrient inadequacy in peri‐urban school children from a district in South India: Potential for staple food fortification and nutrient supplementation
High dietary micronutrient inadequacy in peri‐urban school children from a district in South India: Potential for staple food fortification and nutrient supplementation Open
Multiple micronutrient deficiencies (MNDs) co‐exist, often because of poor intakes and adversely impact health. Habitual diets were assessed in 300 school children (6–17 years old) recruited from two government schools by simple random sam…
View article: Retention, stability, iron bioavailability and sensory evaluation of extruded rice fortified with iron, folic acid and vitamin B<sub>12</sub>
Retention, stability, iron bioavailability and sensory evaluation of extruded rice fortified with iron, folic acid and vitamin B<sub>12</sub> Open
Fortification of rice with micronutrients using extrusion technology is considered a sustainable strategy to prevent nutritional deficiencies in general population. The objective of the present study is to assess the retention, stability a…
View article: Iron and Zinc Bioavailability from Madhukar × Swarna Derived Biofortifed Rice Lines
Iron and Zinc Bioavailability from Madhukar × Swarna Derived Biofortifed Rice Lines Open
Rice is the prime target of biofortification as it provides calories for about half of the world's population.We assessed the iron (Fe) and zinc (Zn) bioavailability from polished rice grains of three high Fe and Zn recombinant inbred line…