Rahat Hadi
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View article: Value of injection of plasma-rich platelets in the vaginal mucosa in cases with vulvovaginal atrophy: a prospective double-blinded randomized controlled study
Value of injection of plasma-rich platelets in the vaginal mucosa in cases with vulvovaginal atrophy: a prospective double-blinded randomized controlled study Open
The study was prospectively registered in the clinical trials registry (NCT03898401) on 19.3.2019, https//clinicaltrials.gov/study/NCT03898401.
View article: Early Results of Using AI in Mammography Screening for Breast Cancer
Early Results of Using AI in Mammography Screening for Breast Cancer Open
Background: Recent advancements in Artificial Intelligence (AI) have the potential to address the challenges of mammographic screening programs by enhancing the performance of Computer-Aided Detection (CAD) systems, improving detection acc…
View article: The Value of Positron Emission Tomography Scan in Staging of Lymphoma in a Sample of Iraqi Patients
The Value of Positron Emission Tomography Scan in Staging of Lymphoma in a Sample of Iraqi Patients Open
Background: A diverse range of illnesses known as lymphomas are caused by immune system constituent cells or their progenitors. 18 F-Fluorodeoxyglucose positron emission tomography (PET)/computerized tomography has been routine practice to…
View article: Pattern of care and clinical outcome of patients with carcinoma endometrium and the impact of central histopathological review on management: A tertiary cancer centre experience
Pattern of care and clinical outcome of patients with carcinoma endometrium and the impact of central histopathological review on management: A tertiary cancer centre experience Open
Purpose/Objective: Endometrial carcinoma (EC) is the third most common gynecological malignancy in India. Recent PORTEC-3 analysis emphasized the role of central histopathological review. We aimed to retrospectively analyze the demographic…
View article: Retrospective analysis of clinical outcome of 100 inoperable oral cavity carcinoma treated with definitive concurrent chemoradiotherapy with or without induction chemotherapy
Retrospective analysis of clinical outcome of 100 inoperable oral cavity carcinoma treated with definitive concurrent chemoradiotherapy with or without induction chemotherapy Open
Inoperable patients of OC-SCC treated with definitive CTRT with or without IC yielded CR in approximately half of patients with acceptable toxicity profiles.
View article: Prophylactic Para-Aortic Extended Field Irradiation with Concurrent Chemotherapy for FIGO Stage IIIC1 Cervical Cancer Using Intensity Modulated Radiotherapy Technique: Acute Toxicity and Dosimetric Assessment
Prophylactic Para-Aortic Extended Field Irradiation with Concurrent Chemotherapy for FIGO Stage IIIC1 Cervical Cancer Using Intensity Modulated Radiotherapy Technique: Acute Toxicity and Dosimetric Assessment Open
View article: Prospective evaluation of dose-escalated preoperative concurrent chemoradiation with image guided-IMRT in locally advanced rectal cancers
Prospective evaluation of dose-escalated preoperative concurrent chemoradiation with image guided-IMRT in locally advanced rectal cancers Open
Dose-escalation of NACRT therapy with IG-IMRT in LARC patients offers decent rates of pCR and overall response with excellent LRC and acceptable toxicities.
View article: Dosimetric Comparision of Coplanar versus Noncoplanar Volumetric Modulated Arc Therapy for Treatment of Bilateral Breast Cancers
Dosimetric Comparision of Coplanar versus Noncoplanar Volumetric Modulated Arc Therapy for Treatment of Bilateral Breast Cancers Open
Introduction: The purpose of this study was to compare the dosimetric parameters of volumetric modulated arc therapy (VMAT) treatment plans using coplanar and noncoplanar beams in patients with bilateral breast cancer/s (BBCs) in terms of …
View article: Whole‐breast irradiation with lumpectomy cavity boost and regional nodal irradiation: Dosimetric comparison of 3D‐CRT using sequential boost and dual partial‐arc VMAT using simultaneous integrated boost
Whole‐breast irradiation with lumpectomy cavity boost and regional nodal irradiation: Dosimetric comparison of 3D‐CRT using sequential boost and dual partial‐arc VMAT using simultaneous integrated boost Open
Objective To compare volumetric modulated arc therapy (VMAT) with simultaneous tumor bed boost (dpSIB‐VMAT) to the whole breast and regional nodal irradiation (RNI) against standard three‐dimensional conformal radiotherapy plus RNI with se…
View article: Circulating free DNA integrity index and promoter methylation of tumor suppressor gene P16, DAPK and RASSF1A as a biomarker for oropharyngeal squamous cell carcinoma
Circulating free DNA integrity index and promoter methylation of tumor suppressor gene P16, DAPK and RASSF1A as a biomarker for oropharyngeal squamous cell carcinoma Open
Circulating free DNA (cfDNA) is in use for the non-invasive diagnosis of tumors. Methylation of tumor suppressor genes (TSGs) is an early event in carcinogenesis and may serve as tumor biomarker. We have investigated cfDNA integrity and me…
View article: Combination of image-guided IMRT and IGBT in locally advanced carcinoma cervix: Prospective evaluation of toxicities and clinical outcomes from a tertiary cancer center in India
Combination of image-guided IMRT and IGBT in locally advanced carcinoma cervix: Prospective evaluation of toxicities and clinical outcomes from a tertiary cancer center in India Open
The combination of IG-IMRT and IGBT yielded excellent outcomes in terms of acute toxicity and loco-regional control.
View article: Long term outcome and late toxicity Of SIB-IMRT in definitive management of head and neck cancers in patients not suitable for chemo-radiotherapy
Long term outcome and late toxicity Of SIB-IMRT in definitive management of head and neck cancers in patients not suitable for chemo-radiotherapy Open
Objective: To evaluate efficacy and late toxicity of intensity-modulated radiotherapy with simultaneous integrated boost (IMRT-SIB) in definitive management of head-and-neck cancers. Methods: In this prospective interventional study, histo…
View article: A Study of Multivariate Modalities of Therapy in Gall Bladder Malignancies with Different Clinical, Radiological and Histo-Pathological Profiles at a Low Resource Indian Cancer Centre
A Study of Multivariate Modalities of Therapy in Gall Bladder Malignancies with Different Clinical, Radiological and Histo-Pathological Profiles at a Low Resource Indian Cancer Centre Open
Introduction: The effectiveness of adjuvant radiation therapy (RT) in the treatment of GBC has not yet been established. The effectiveness of adjuvant radiation therapy (RT) in the treatment of GBC has not yet been established. Following s…
View article: Optimum Radiation Fractionation Schedule in Advanced Cancer Cervix; A Study from Low Resource North Indian Cancer Center
Optimum Radiation Fractionation Schedule in Advanced Cancer Cervix; A Study from Low Resource North Indian Cancer Center Open
Introduction: Cervical cancer is the fourth most commonly occurring lethal cancer among women worldwide. The primary curative treatment option for women suffering from locally advanced cervical cancer includes external beam radiotherapy (E…
View article: Programmed Death Ligand 1 Expression in Lung Adenocarcinoma: An Analysis of the Histomorphological Features
Programmed Death Ligand 1 Expression in Lung Adenocarcinoma: An Analysis of the Histomorphological Features Open
Background: Immunotherapy is now a vital target therapy in the advanced cases of lung adenocarcinoma. The outstanding result of therapies with medications that inhibit the interaction of programmed death ligand 1 with programmed death prot…
View article: Evaluation of Doses to Target Volume and Organs at Risk by Conventional versus RTOG Contouring Based 3D Conformal Plans in Breast Cancer: A Prospective Study
Evaluation of Doses to Target Volume and Organs at Risk by Conventional versus RTOG Contouring Based 3D Conformal Plans in Breast Cancer: A Prospective Study Open
Introduction: In radiotherapy, conventional field borders have often little anatomical correlation with the draining lymphatics. So, with the availability of more conformal techniques and delineation guidelines, an evident need exists to o…
View article: Correlation of PD-L1 expression with toxicities and responsein oropharyngeal cancers treated with definitive chemoradiotherapy
Correlation of PD-L1 expression with toxicities and responsein oropharyngeal cancers treated with definitive chemoradiotherapy Open
Positive PD-L1 expression is associated with fewer acute radiation toxicities, and this could be used as a potential biomarker.
View article: Clinical Outcome of Inoperable Locally Advanced Carcinoma of Oral Cavity Treated With Definitive Concurrent Chemoradiotherapy: A Retrospective Analysis From Tertiary Cancer Center
Clinical Outcome of Inoperable Locally Advanced Carcinoma of Oral Cavity Treated With Definitive Concurrent Chemoradiotherapy: A Retrospective Analysis From Tertiary Cancer Center Open
View article: Evaluation of Molecular Positive Margins Using Surrogate P53 and Retinoblastoma Protein Expression and Correlation with Surgical Outcomes in Oral Squamous Cell Carcinoma
Evaluation of Molecular Positive Margins Using Surrogate P53 and Retinoblastoma Protein Expression and Correlation with Surgical Outcomes in Oral Squamous Cell Carcinoma Open
BACKGROUND p53 mutation and Rb over-expression have been extensively studied in oral squamous cell carcinoma (OSCC) but their clinical relevance with respect to excision margins is still controversial. The purpose of the study was to deter…
View article: Study of toxicities of Intensity Modulated Radiotherapy (IMRT) in post-operative patients of carcinoma cervix and endometrium
Study of toxicities of Intensity Modulated Radiotherapy (IMRT) in post-operative patients of carcinoma cervix and endometrium Open
Background Various studies have shown a clinical benefit of pelvic IMRT but included a significant number of patients with intact cervix and uterus. Therefore we proposed a prospective study to evaluate the toxicity, feasibility, and toler…
View article: Evaluation of clinical implications in the use of dose to water versus dose to medium by using NTCP and TCP models for urinary bladder tumours
Evaluation of clinical implications in the use of dose to water versus dose to medium by using NTCP and TCP models for urinary bladder tumours Open
Purpose: To analyze the dosimetric and radiobiological differences between dose to water versus dose to medium for patients with carcinoma of the urinary bladder. Materials and Methods: 15 patients with cancer of urinary bladder were selec…
View article: Evaluation of dosimetric implications of Pareto and constrained mode of optimization for Monaco TPS generated VMAT plans in post operated carcinoma of the left breast
Evaluation of dosimetric implications of Pareto and constrained mode of optimization for Monaco TPS generated VMAT plans in post operated carcinoma of the left breast Open
Intensity-modulated radiotherapy (IMRT) is being practiced for the last several years with a special approach for radiation therapy in post-mastectomy breast cancer patients. Meeting the cardiac dose constraints has always been a challenge…
View article: A Cohort Study of Toxicities of Intensity Modulated Radiotherapy in Postoperative Patients of Carcinoma Cervix and Endometrium
A Cohort Study of Toxicities of Intensity Modulated Radiotherapy in Postoperative Patients of Carcinoma Cervix and Endometrium Open
Introduction: Conventional Whole Pelvic Radiotherapy (WPRT) is associated with significant morbidity, especially haematological and Gastrointestinal (GI), which increases further with concurrent chemotherapy. Various studies have shown a c…
View article: Island Nasolabial Flap for Tongue Reconstruction: Locoregional Flap of Choice and an Alternative to Free Flap for Tongue Cancer
Island Nasolabial Flap for Tongue Reconstruction: Locoregional Flap of Choice and an Alternative to Free Flap for Tongue Cancer Open
View article: Patterns of failure and clinical outcomes of post-operative buccal mucosa cancers treated with adjuvant ipsilateral radiotherapy
Patterns of failure and clinical outcomes of post-operative buccal mucosa cancers treated with adjuvant ipsilateral radiotherapy Open
Incidence of contralateral recurrence with ipsilateral irradiation in buccal mucosa cancers is low with descent survival outcomes, particularly in node negative cases.
View article: Evaluation of the effect of random setup errors on dose delivery in Intensity Modulated Radiotherapy
Evaluation of the effect of random setup errors on dose delivery in Intensity Modulated Radiotherapy Open
Aim: To conduct a study on the effect of random setup errors inpatient for dose delivery in Intensity Modulated Radiotherapy plans using Octavius 4D phantom. Materials and methods: 11 patients with cancer of H&N were selected for this stud…
View article: Interaction of glutathione‐s‐transferase genotypes with environmental risk factors in determining susceptibility to head and neck cancer and treatment response and survival outcome
Interaction of glutathione‐s‐transferase genotypes with environmental risk factors in determining susceptibility to head and neck cancer and treatment response and survival outcome Open
The present case‐control study aimed to investigate the role of interaction of glutathione‐s‐transferase (GST) genotypes with environmental risk factors in determining susceptibility to head and neck squamous cell carcinoma (HNSCC) involvi…
View article: Treatment Pattern and Outcomes in Verrucous Carcinoma of Oral Cavity: A Single Institutional Retrospective Analysis from a Tertiary Cancer Center and Review of Literature
Treatment Pattern and Outcomes in Verrucous Carcinoma of Oral Cavity: A Single Institutional Retrospective Analysis from a Tertiary Cancer Center and Review of Literature Open
View article: The Role of Circulating Tumour DNA as a Marker of Adequate Resection in Oral Cancer and its Correlation with Clinico-pathologic Parameters: A Prospective Study
The Role of Circulating Tumour DNA as a Marker of Adequate Resection in Oral Cancer and its Correlation with Clinico-pathologic Parameters: A Prospective Study Open
Introduction: Oral Cavity Squamous Cell Carcinoma (OSCC) is prevalent worldwide. The genetic heterogeneity of this disease and the limitation of biopsy in selective mapping, made use of conventional biopsy sub-optimal for advanced molecula…
View article: Kirsten rat sarcoma virus protein overexpression in adenocarcinoma lung: Association with clinicopathological and histomorphological features
Kirsten rat sarcoma virus protein overexpression in adenocarcinoma lung: Association with clinicopathological and histomorphological features Open
This finding may imply that KRAS mutations may not be entirely triggered by alterations induced by carcinogens in smoke. KRAS gene is frequently mutated in pulmonary tumors. It should be tested in NSCLC owing to its predictive and prognost…