Explanipedia

Electrical stimulation for the induction of seizures is safe, well-tolerated and high-yield in children with drug-resistant epilepsy Open

Lucy Tarcha, Ravindra Arya, S. Katie Z. Ihnen · 2025

A STUDY OF HISTOPATHOLOGICAL VARIANTS OF SQUAMOUS CELL CARCINOMA IN DOGS Open

Yash Bhate Abhay, Diksha Singh, Vivek Chaturvedi, Shyama N. Prabhu, Ajay P. Singh , et al. · 2025

Comparative efficacy of neuromodulation therapies in Lennox–Gastaut syndrome: A systematic review and meta‐analysis of vagus nerve stimulation, deep brain stimulation, and responsive neurostimulation Open

Debopam Samanta, Puneet Jain, Jessie Cunningham, Ravindra Arya · 2025

Objective Lennox–Gastaut syndrome (LGS) is a childhood onset developmental and epileptic encephalopathy characterized by multiple seizure types that are often refractory to traditional antiseizure medications. Neuromodulation therapies inc…

Electrical Stimulation for the Induction of Seizures is Safe, Well-tolerated and High-Yield in Children with Drug-Resistant Epilepsy Open

Lucy Tarcha, Darcy A. Krueger, Hansel M. Greiner, Jesse Skoch, Francesco T. Mangano , et al. · 2025

Introduction One third of children with epilepsy develop drug-resistant epilepsy (DRE). Epilepsy surgery is the treatment for DRE, and selecting the surgical target typically requires recording spontaneous seizures during intracranial moni…

Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms Open

Rachata Boonkrongsak, Kantapon Trongkamolchai, Sirorat Suwannachote, Somjit Sri-Udomkajorn, Raviwan Wittawassamrankul , et al. · 2025

Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized t…

Optimizing root architecture: unlocking water and mineral mining for enhanced legume yields Open

B. Mishra, M Chaturvedi, Ravindra Arya, Ravi Pratap Singh · 2024

High‐gamma modulation language mapping and cognitive outcomes after epilepsy surgery Open

Brian Ervin, Christina Kargol, Anna W. Byars, Jason Buroker, Leonid Rozhkov , et al. · 2024

Objective We evaluated changes in cognitive domains after neurosurgical lesioning of cortical sites with significant high‐gamma power modulations (HGM) during a visual naming task, although these sites were found language‐negative on stand…

Excess soil moisture stress in maize: Physiological mechanisms and adaptive strategies Open

B. Mishra, M Chaturvedi, Ravindra Arya, Ravi Pratap Singh, Gaurav Yadav · 2024

Neuropsychological outcomes after epilepsy surgery: A comparison of stereo electroencephalography and subdural electrodes Open

Ravindra Arya, Clayton Frink, Christina Kargol, Anna W. Byars, David A. Huddleston , et al. · 2023

Background and purpose We analyzed the association of neuropsychological outcomes after epilepsy surgery with the intracranial electrode type (stereo electroencephalography [SEEG] and subdural electrodes [SDE]), and electrical stimulation …

Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children Open

Katrina Peariso, Ravindra Arya, Tracy A. Glauser, Nicholas S. Abend, Cristina Barcia Aguilar , et al. · 2023

This study provides Class II evidence that patient and clinical factors may predict RSE in children with convulsive seizures.

Comparing electrical stimulation functional mapping with subdural electrodes and stereoelectroencephalography Open

Gewalin Aungaroon, Kishore Vedala, Anna W. Byars, Brian Ervin, Leonid Rozhkov , et al. · 2023

Objective Electrical stimulation mapping (ESM) is the clinical standard for functional localization with subdural electrodes (SDE). As stereoelectroencephalography (SEEG) has emerged as an alternative option, we compared functional respons…

Comparison of outcomes after stereoelectroencephalography and subdural grid monitoring in pediatric tuberous sclerosis complex Open

Thomas Larrew, Jesse Skoch, S. Katie Z. Ihnen, Ravindra Arya, Katherine D. Holland , et al. · 2022

OBJECTIVE Patients with tuberous sclerosis complex (TSC) epilepsy present with unique clinical challenges such as early seizure onset and high rates of intractability and multifocality. Although there are numerous studies about the safety …

Treatment of benzodiazepine-resistant status epilepticus: Systematic review and network meta-analyses Open

Puneet Jain, Satinder Aneja, Jessie Cunningham, Ravindra Arya, Suvasini Sharma · 2022

Posterior Quadrant Disconnection Procedure for Intractable Epilepsy: A Case Series of 5 Young Pediatric Patients Open

Smruti Patel, Justin Gibson, Mykhailo Lovha, James L. Leach, Ravindra Arya , et al. · 2022

BACKGROUND: Posterior quadrant disconnection (PQD) has been described as a treatment for patients with refractory posterior quadrant subhemispheric epilepsy. Surgical outcomes are difficult to interpret because of limited literature. OBJEC…

0830 A Pediatric Case of Myoclonic Seizures Precipitating Central Sleep Apnea And Sequences of Periodic Breathing During Sleep Open

Benjamin Wisniewski, Rochelle Witt, Thomas J. Dye, Ravindra Arya, Narong Simakajornboon · 2022

Introduction Myoclonic seizures are known to be influenced by the sleep-wake cycle. Although myoclonic seizures have been shown to alter sleep architecture, little is known about their influence on sleep-disordered breathing. Report of Cas…

Neuronal Circuits Supporting Development of Visual Naming Revealed by Intracranial Coherence Modulations Open

Ravindra Arya, Brian Ervin, Jason Buroker, Hansel M. Greiner, Anna W. Byars , et al. · 2022

Background Improvement in visual naming abilities throughout the childhood and adolescence supports development of higher-order linguistic skills. We investigated neuronal circuits underlying improvement in the speed of visual naming with …

A distributed network supports spatiotemporal cerebral dynamics of visual naming Open

Brian Ervin, Jason Buroker, Anna W. Byars, Leonid Rozhkov, James L. Leach , et al. · 2021

Benzodiazepine administration patterns before escalation to second‐line medications in pediatric refractory convulsive status epilepticus Open

Theodore Sheehan, Marta Amengual‐Gual, Alejandra Vasquez, Nicholas S. Abend, Anne E. Anderson , et al. · 2021

Objective This study was undertaken to evaluate benzodiazepine (BZD) administration patterns before transitioning to non‐BZD antiseizure medication (ASM) in pediatric patients with refractory convulsive status epilepticus (rSE). Methods Th…

Treatments for subacute sclerosing panencephalitis Open

Lakshminarayanan Kannan, Sushil Kumar Garg, Ravindra Arya, Mari Jeeva Sankar, Vidhu Anand · 2021

This protocol for a Cochrane Review is out of date and has been withdrawn in order to adhere to Cochrane policy.

Factors associated with long‐term outcomes in pediatric refractory status epilepticus Open

Marina Gaínza‐Lein, Cristina Barcia Aguilar, Juan Piantino, Kevin Chapman, Iván Sánchez Fernández , et al. · 2021

Objective This study was undertaken to describe long‐term clinical and developmental outcomes in pediatric refractory status epilepticus (RSE) and identify factors associated with new neurological deficits after RSE. Methods We performed r…

Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort) Open

Claudine Sculier, Cristina Barcia Aguilar, Nicolas Gaspard, Marina Gaínza‐Lein, Iván Sánchez Fernández , et al. · 2021

Objective We aimed to characterize the clinical profile and outcomes of new onset refractory status epilepticus (NORSE) in children, and investigated the relationship between fever onset and status epilepticus (SE). Methods Patients with r…

Spatial-Temporal Functional Mapping Combined With Cortico-Cortical Evoked Potentials in Predicting Cortical Stimulation Results Open

Yujing Wang, Mark Hays, Christopher Coogan, Joon Y. Kang, Adeen Flinker , et al. · 2021

Functional human brain mapping is commonly performed during invasive monitoring with intracranial electroencephalographic (iEEG) electrodes prior to resective surgery for drug resistant epilepsy. The current gold standard, electrocortical…

Underutilization of epilepsy surgery: Part II: Strategies to overcome barriers Open

Debopam Samanta, Rani K. Singh, Satyanarayana Gedela, Μ. Scott Perry, Ravindra Arya · 2021

Underutilization of epilepsy surgery: Part I: A scoping review of barriers Open

Debopam Samanta, Adam P. Ostendorf, Erin Willis, Rani K. Singh, Satyanarayana Gedela , et al. · 2021

Electrical Stimulation Mapping of Brain Function: A Comparison of Subdural Electrodes and Stereo-EEG Open

Krista M. Grande, S. Katie Z. Ihnen, Ravindra Arya · 2020

Despite technological and interpretative advances, the non-invasive modalities used for pre-surgical evaluation of patients with drug-resistant epilepsy (DRE), fail to generate a concordant anatomo-electroclinical hypothesis for the locati…

First-line medication dosing in pediatric refractory status epilepticus Open

Alejandra Vasquez, Marina Gaínza‐Lein, Nicholas S. Abend, Marta Amengual‐Gual, Anne E. Anderson , et al. · 2020

This study provides Class III evidence that patients with RSE who present with male sex, older age, no prior diagnosis of epilepsy, and delayed BZD treatment are more likely to receive low total BZD doses. This study provides Class III evi…

Association of guideline publication and delays to treatment in pediatric status epilepticus Open

Iván Sánchez Fernández, Nicholas S. Abend, Marta Amengual‐Gual, Anne E. Anderson, Ravindra Arya , et al. · 2020

Publication of evidence on delays in time to treatment was not associated with improvements in time to treatment of rSE, although it was associated with an increase in the proportion of patients who received at least 1 BZD before hospital …

KCNT1‐related epilepsy: An international multicenter cohort of 27 pediatric cases Open

Felippe Borlot, Ahmed Abushama, Nadine Morrison‐Levy, Puneet Jain, Kollencheri Puthenveettil Vinayan , et al. · 2020

Objective Through international collaboration, we evaluated the phenotypic aspects of a multiethnic cohort of KCNT1‐related epilepsy and explored genotype‐phenotype correlations associated with frequently encountered variants. Methods A cr…

Refractory and Super-refractory Status Epilepticus Open

Debopam Samanta, Lisa Garrity, Ravindra Arya · 2020

Development of information sharing in language neocortex in childhood‐onset drug‐resistant epilepsy Open

Ravindra Arya, Brian Ervin, J. Adam Wilson, Anna W. Byars, Leonid Rozhkov , et al. · 2019

Summary Objective We studied age‐related dynamics of information sharing among cortical language regions with electrocorticographic high‐gamma modulation during picture‐naming and story‐listening tasks. Methods Seventeen epilepsy patients …

Ravindra Arya YOU? Author Swipe