Rahul S. Tare
YOU?
Author Swipe
View article: Temporal analysis of bone development in chick femur bone using label-free imaging
Temporal analysis of bone development in chick femur bone using label-free imaging Open
View article: A scaffold-free approach to cartilage tissue generation using human embryonic stem cells
A scaffold-free approach to cartilage tissue generation using human embryonic stem cells Open
View article: Live-imaging of Bioengineered Cartilage Tissue using Multimodal Non-linear Molecular Imaging
Live-imaging of Bioengineered Cartilage Tissue using Multimodal Non-linear Molecular Imaging Open
Coherent anti-Stokes Raman scattering (CARS) and second harmonic generation (SHG) are non-linear techniques that allow label-free, non-destructive and non-invasive imaging for cellular and tissue analysis. Although live-imaging studies hav…
View article: Augmentation of Musculoskeletal Regeneration: Role for Pluripotent Stem Cells
Augmentation of Musculoskeletal Regeneration: Role for Pluripotent Stem Cells Open
The rise in the incidence of musculoskeletal diseases is attributed to an increasing ageing population. The debilitating effects of musculoskeletal diseases, coupled with a lack of effective therapies, contribute to huge financial strains …
View article: Quantitative temporal interrogation in 3D of bioengineered human cartilage using multimodal label-free imaging
Quantitative temporal interrogation in 3D of bioengineered human cartilage using multimodal label-free imaging Open
Multimodal label-free molecular imaging allows 3D phenotypic characterisation and quantitation of bioengineered cartilage non-invasively and non-destructively.
View article: Acoustically modulated biomechanical stimulation for human cartilage tissue engineering
Acoustically modulated biomechanical stimulation for human cartilage tissue engineering Open
The biomechanical environment in an acoustofluidic bioreactor is modified by controlling the acoustic driving conditions to promote human cartilage generation.
View article: Mesenchymal Stem Cells: Potential Role in the Treatment of Osteochondral Lesions of the Ankle
Mesenchymal Stem Cells: Potential Role in the Treatment of Osteochondral Lesions of the Ankle Open
Given articular cartilage has a limited repair potential, untreated osteochondral lesions of the ankle can lead to debilitating symptoms and joint deterioration necessitating joint replacement. While a wide range of reparative and restorat…
View article: PEGylated Liposomes Associate With Wnt3A Protein and Expand Putative Stem Cells in Human Bone Marrow Populations
PEGylated Liposomes Associate With Wnt3A Protein and Expand Putative Stem Cells in Human Bone Marrow Populations Open
Aim: To fabricate PEGylated liposomes which preserve the activity of hydrophobic Wnt3A protein, and to demonstrate their efficacy in promoting expansion of osteoprogenitors from human bone marrow. Methods: PEGylated liposomes composed of s…
View article: Generation of a Bag1 homozygous knockout mouse embryonic stem cell line using CRISPR/Cas9
Generation of a Bag1 homozygous knockout mouse embryonic stem cell line using CRISPR/Cas9 Open
Bag1 transcribes a multifunctional protein that participates in many important biological processes such as cell apoptosis, proliferation, differentiation and embryo development. Despite numerous published studies, the role of Bag1 in the …
View article: Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1)
Regulation of osteoblast development by Bcl-2-associated athanogene-1 (BAG-1) Open
BCL-2-associated athanogene-1 (BAG-1) is expressed by osteoblast-lineage cells; early embryonic lethality in Bag-1 null mice, however, has limited the investigation of BAG-1 function in osteoblast development. In the present study, bone mo…
View article: Raman spectroscopy and coherent anti-Stokes Raman scattering imaging: prospective tools for monitoring skeletal cells and skeletal regeneration
Raman spectroscopy and coherent anti-Stokes Raman scattering imaging: prospective tools for monitoring skeletal cells and skeletal regeneration Open
The use of skeletal stem cells (SSCs) for cell-based therapies is currently one of the most promising areas for skeletal disease treatment and skeletal tissue repair. The ability for controlled modification of SSCs could provide significan…
View article: Extracellular Matrix Deposition in Engineered Micromass Cartilage Pellet Cultures: Measurements and Modelling
Extracellular Matrix Deposition in Engineered Micromass Cartilage Pellet Cultures: Measurements and Modelling Open
This article explores possible mechanisms governing extracellular matrix deposition in engineered cartilaginous cell pellets. A theoretical investigation is carried out alongside an experimental study measuring proteoglycan and collagen vo…
View article: Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors
Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors Open
Activation of the canonical Wnt signaling pathway is an attractive anabolic therapeutic strategy for bone. Emerging data suggest that activation of the Wnt signaling pathway promotes bone mineral accrual in osteoporotic patients. The effec…
View article: Bone Tissue Engineering
Bone Tissue Engineering Open
Medical advances have led to a welcome increase in life expectancy. However, accompanying longevity introduces new challenges: increases in age-related diseases and associated reductions in quality of life. The loss of skeletal tissue that…
View article: Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging
Tracking adipogenic differentiation of skeletal stem cells by label-free chemically selective imaging Open
CARS imaging proves to be a powerful, sensitive and label-free tool for studying adipogenesis in skeletal stem cells.