Explanipedia

A Qualitative Study on Perspectives of Parkinson’s Disease Medications: Insights from Patient Focus Groups Open

Kristin V. Richards, Sneha Mantri, Carolyn M. Brown, Michael Johnsrud, Steve Arcona , et al. · 2024

This study identified four core dimensions associated with PD medications from the perspective of PwPD. Results indicate the need for enhanced communication between providers and patients regarding PD medication to reduce the uncertainties…

Association Between Persistence with Oral Atypical Antipsychotic Medications and Hospital and Emergency Department Utilization in Medicaid Patients with Schizophrenia Open

Kristin V. Richards, Michael Johnsrud, Christopher Zacker, Rahul Sasané · 2024

Non-persistence with OAAP medication is common among patients with schizophrenia and associated with negative outcomes including increased utilization of hospital and ED resources. Patient-centered interventions that improve antipsychotic …

One-Year Medication Treatment Patterns, Healthcare Resource Utilization, and Expenditures for Medicaid Patients with Schizophrenia Starting Oral Atypical Antipsychotic Medication Open

Kristin V. Richards, Michael Johnsrud, Christopher Zacker, Rahul Sasané · 2023

Treatment Patterns and Healthcare Resource Use in Medicare Beneficiaries with Parkinson’s Disease Open

Yan Song, E Jian‐Yu, Tracy Guo, Rahul Sasané, Steve Arcona , et al. · 2023

While levodopa is still the mainstay of PD management, considerable heterogeneity exists in real-world treatment patterns. Overall, PD symptoms and AEs were associated with significantly higher HRU and healthcare costs, suggesting unmet me…

Work Loss and Direct and Indirect Costs Associated with Parkinson’s Disease Open

Michelle Jerry, Steve Arcona, Donna McMorrow, Hana Schwartz, Nicole Princic , et al. · 2023

PD has both a significant direct and indirect financial burden on patients and their spouses when analyzed for 3 years before and after diagnosis.

Dopamine agonist monotherapy utilization in patients with Parkinson’s disease Open

Monica Frazer, Steve Arcona, Lisa W. Le, Rahul Sasané · 2022

Exploring access to care from the perspective of patients with breast cancer: A qualitative study Open

Carolyn M. Brown, Chisom Kanu, Kristin M. Richards, Laura Stevens, Rahul Sasané , et al. · 2022

Objectives Patients face a myriad of personal and system‐based challenges in accessing breast cancer care, but less is known about access as expressed and experienced by patients themselves. The objective of this qualitative study was to f…

Levodopa treatment patterns in Parkinson’s disease: A retrospective chart review Open

Prakash Navaratnam, Steve Arcona, Howard S. Frıedman, Matthew Leoni, Rahul Sasané · 2022

Prescribers and patients tend to experiment with levodopa-PDDI treatment. Although many patients appeared to stop levodopa-PDDI after an initial course of treatment, most subsequently restarted treatment.

Natural history and patterns of treatment change in Parkinson’s disease: A retrospective chart review Open

Prakash Navaratnam, Steve Arcona, Howard S. Frıedman, Matthew Leoni, Shajahan Shaik , et al. · 2021

Parkinson disease among patients treated for benign prostatic hyperplasia with α1 adrenergic receptor antagonists Open

Rahul Sasané, A Bartels, Michelle Field, Maria I. Sierra, Sridhar Duvvuri , et al. · 2021

BACKGROUNDRecently the α1 adrenergic receptor antagonist terazosin was shown to activate PGK1, a possible target for the mitochondrial deficits in Parkinson disease related to its function as the initial enzyme in ATP synthesis during glyc…

An assessment of Parkinson’s disease medication treatment patterns in the Medicaid population Open

Michael Johnsrud, Kristin M. Richards, Steve Arcona, Rahul Sasané, Matthew Leoni · 2021

Evaluation of access to care issues in patients with breast cancer Open

Carolyn M. Brown, Kristin M. Richards, Yogesh Vohra, Chisom Kanu, Laura Stevens , et al. · 2020

Access to care overall and by factor was significantly predictive of patient satisfaction with care. In addition, access to care factors varied across several demographic and clinical characteristics. Future strategies that address access …

Drug Treatment Value in a Changing Oncology Landscape: A Literature and Provider Perspective Open

C. Frois, A Howe, John Jarvis, Kathryn Le Grice, Ken Wong , et al. · 2019

Funding for this work was provided by Novartis Pharmaceuticals. The study sponsor was involved in study design, data interpretation, and data review. All authors contributed to the development of the manuscript and maintained control over …

A Review Of Factors Associated With Access To Care In Breast Cancer Patients Open

CM Brown, Katherine Richards, CN Kanu, Rahul Sasané, DH Tang , et al. · 2018

Medical Resource Utilization and Expenditures in Texas Medicaid Patients Taking Deferasirox Dispersible Tablets and Those Taking Deferasirox Film-Coated Tablets Open

Kelly Richards, KA Lawson, Q Said, Rahul Sasané · 2018

Outcomes-Based Contracting Experience: Research Findings from U.S. and European Stakeholders Open

Tara Nazareth, John J. Ko, Rahul Sasané, C. Frois, Stephen Carpenter , et al. · 2017

This study was funded by Novartis Pharmaceuticals. Novartis employees were involved in all aspects of this study. Vegesna and Sasane are employed by and own stock in Novartis. Nazareth and Ko were employees of Novartis at the time of this …

Associations Between Treatment Satisfaction, Medication Beliefs, and Adherence to Disease-Modifying Therapies in Patients with Multiple Sclerosis Open

Andrew Thach, Carolyn M. Brown, Vivian Herrera, Rahul Sasané, Jamie C. Barner , et al. · 2017

Background: Adherence to disease-modifying therapy (DMT) remains problematic for many patients with multiple sclerosis (MS). An improved understanding of factors affecting DMT adherence may inform effective interventions. This study examin…

Persistency, medication prescribing patterns, and medical resource use associated with multiple sclerosis patients receiving oral disease-modifying therapies: a retrospective medical record review Open

Tara Nazareth, Howard S. Frıedman, Prakash Navaratnam, Denise A. Herriott, John J. Ko , et al. · 2016

The real-world patient experience of fingolimod and dimethyl fumarate for multiple sclerosis Open

Paul Wicks, Lawrence Rasouliyan, Bo Katic, Beenish Nafees, Emuella Flood , et al. · 2016

Increasing Patient Involvement in Drug Development Open

Maria Lowe, David A. Blaser, Lisa Cone, Steve Arcona, John J. Ko , et al. · 2016

As health care systems continue to evolve and establish patients as the primary stakeholder in their health care decision making, the pharmaceutical industry will need to be innovative to demonstrate the value of their products relative to…

Prevalence And Incidence Of Attention Deficit Hyperactivity Disorder Among Texas Medicaid Preschoolers Open

RR Singh, KA Lawson, JC Barner, KM Richards, Rahul Sasané , et al. · 2016

OUTCOMES-BASED ARRANGEMENTS IN VALUE-BASED CARE: AN ENGAGEMENT FRAMEWORK Open

Tara Nazareth, Tzu‐Ying Yu, C. Brunken, Steve Arcona, Rahul Sasané , et al. · 2016

Additional file 1: of Persistency, medication prescribing patterns, and medical resource use associated with multiple sclerosis patients receiving oral disease-modifying therapies: a retrospective medical record review Open

Tara Nazareth, Howard S. Frıedman, Prakash Navaratnam, Denise Herriott, John J. Ko , et al. · 2016

Multiple sclerosis patients receiving oral disease-modifying therapies medical record review. Data file contains multiple-sclerosis patient medical record reviews. Each row is a distinct patient. Columns reflect information about the patie…

Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis Open

Shahamat Tauhid, Renxin Chu, Rahul Sasané, Bonnie I. Glanz, Mohit Neema , et al. · 2015

Preferred Features of Oral Treatments and Predictors of Non-Adherence: Two Web-Based Choice Experiments in Multiple Sclerosis Patients Open

Paul Wicks, David Brandes, Jinhee Park, Dimitri Liakhovitski, Tatiana Koudinova , et al. · 2015

Understanding the important concerns expressed by patients may help health care providers to understand and educate their patients more completely about these concerns. This knowledge may therefore improve both choices of appropriate thera…

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