Raiza Maia
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View article: Membrane composition reshapes the folding landscape of a pH-responsive peptide
Membrane composition reshapes the folding landscape of a pH-responsive peptide Open
Lipid composition drives membrane protein sorting, interactions, and function, but the precise mechanistic influence of the membrane on protein free energy landscapes remains largely unresolved. In this study, we probe how lipids reshape t…
View article: A lipid replicator drives protocell reproduction
A lipid replicator drives protocell reproduction Open
Lipid compartmentalization is a universal feature of living systems. As a result, understanding how lipid compartments can propagate over time is a central challenge in origins of life research. Current models rely on physical autocatalysi…
View article: Solvent Reorganization in Stabilized Protein-Polymer Conjugates Visualized by 2D IR and NMR Spectroscopy
Solvent Reorganization in Stabilized Protein-Polymer Conjugates Visualized by 2D IR and NMR Spectroscopy Open
PEGylation is essential for effective function of biologics, shielding them from rapid degradation and clearance in the complex environment of the human body. Despite its significance, a mechanistic understanding of PEGylation’s role in en…
View article: Capturing the blue-light activated state of the Phot-LOV1 domain from <i>Chlamydomonas reinhardtii</i> using time-resolved serial synchrotron crystallography
Capturing the blue-light activated state of the Phot-LOV1 domain from <i>Chlamydomonas reinhardtii</i> using time-resolved serial synchrotron crystallography Open
Light–oxygen–voltage (LOV) domains are small photosensory flavoprotein modules that allow the conversion of external stimuli (sunlight) into intracellular signals responsible for various cell behaviors ( e.g. phototropism and chloroplast r…
View article: Capturing the blue-light activated state of the Phot-LOV1 domain from<i>Chlamydomonas reinhardtii</i>using time-resolved serial synchrotron crystallography
Capturing the blue-light activated state of the Phot-LOV1 domain from<i>Chlamydomonas reinhardtii</i>using time-resolved serial synchrotron crystallography Open
Light-Oxygen-Voltage (LOV) domains are small photosensory flavoprotein modules that allow converting external stimuli (sunlight) into intracellular signals responsible for various cell behavior ( e . g., phototropism and chloroplast reloca…
View article: Molecular details of the unique mechanism of chloride transport by a cyanobacterial rhodopsin
Molecular details of the unique mechanism of chloride transport by a cyanobacterial rhodopsin Open
An aspartic acid (D85) becomes deprotonated during chloride transport by this cyanobacterial rhodopsin, which possibly serves as a regulatory mechanism.