Explanipedia

Pattern and Severity of Substance Use Disorder among Patients Seeking Treatment at De-addiction Centres in District Amritsar, Punjab Open

Priyanka Devgun, Manisha Nagpal, Davinder Singh Bajwa, Harleen Kaur Ghara, Riya Gupta , et al. · 2025

Introduction: Worldwide substance use is a major public health problem. There are multiple socio-demographic correlates of substance use disorders. Objective: To study pattern and severity of substance use disorder (SUD) among patients see…

Abnormal electrocardiogram findings in athletes Open

Giuseppe Finocchiaro, Alessandro Zorzi, Mark Abela, Aaron L. Baggish, Silvia Castelletti , et al. · 2025

Athletes commonly exhibit a series of electrical, structural, and functional physiological changes which may overlap with cardiac pathology. The last two decades have witnessed a progressive improvement in understanding what can be conside…

7-042 Age related changes in ECG parameters in elite football players Open

Kentaro Yamagata, Daniel Augustine, Michael Bowes, Paul Clift, Robert G. Cooper , et al. · 2025

7-011 Electrocardiographic findings of elite British basketball players compared to elite British footballers using the international criteria for ECG interpretation in athletes Open

Tanisha Burgher, Kentaro Yamagata, Markos Reissis, Hossein Baghertash, Andrew Howse , et al. · 2025

Abnormal Pre-Participation Cardiac Screening in Athletes Open

Raghav Bhatia, Sanjay Sharma, Michael Papadakis, Peter N. Dean, Hamish MacLachlan , et al. · 2025

Echocardiography in the cardiac assessment of young athletes: a 2025 guideline from the British Society of Echocardiography (endorsed by Cardiac Risk in the Young) Open

David Oxborough, Keith George, Robert Cooper, Raghav Bhatia, Tristan Ramcharan , et al. · 2025

High intensity exercise programme in patients with hypertrophic cardiomyopathy: a randomized trial Open

Joyee Basu, Dimitra Nikoletou, Chris Miles, Hamish MacLachlan, Gemma Parry‐Williams , et al. · 2025

Background and Aims The feasibility and impact of high intensity exercise programmes in patients with hypertrophic cardiomyopathy (HCM) are unknown. This study was conducted to determine the feasibility of a high intensity exercise program…

Influence of age and sex on the diagnostic yield of inherited cardiac conditions in sudden arrhythmic death syndrome decedents Open

Belinda Gray, Elijah R. Behr, Efstathios Papatheodorou, Athanasios Bakalakos, Hariharan Raju , et al. · 2024

Aims Sudden arrhythmic death syndrome (SADS) refers to a sudden death, which remains unexplained despite comprehensive post-mortem examination and a toxicological screen. We aimed to investigate the impact of age and sex on the overall dia…

Considerations for drug trials in hypertrophic cardiomyopathy Open

J. Farrant, Matthias Schmitt, Anna Reid, Clifford J. Garratt, William G. Newman , et al. · 2024

Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden car…

Return-to-Play Post-Myocarditis for Athletes: To Play or Not to Play? Open

Kentaro Yamagata, Aneil Malhotra · 2024

Myocarditis is a condition marked by inflammation of the heart muscle, which can lead to serious outcomes such as sudden cardiac death (SCD) and life-threatening arrhythmias. While myocarditis can affect any population, athletes, especiall…

The future of education in Preventive Cardiology: a statement of the European Association of Preventive Cardiology of the European Society of Cardiology Open

Konstantinos C. Koskinas, Matthias Wilhelm, Martin Halle, Alessandro Biffi, Elena Cavarretta , et al. · 2024

In recent years, major advances in our understanding of risk factors implicated in the development of cardiovascular disease (CVD), in available tools for early detection of CVD, and in effective interventions to prevent subclinical or cli…

Left ventricular morphology and geometry in élite athletes characterised by extreme anthropometry Open

Eleonora Moccia, Harshil Dhutia, Aneil Malhotra, Efstathios Papatheodorou, Elijah R. Behr , et al. · 2024

Athletes with high BMI have similar LV dimensions but greater wall thickness and higher prevalence of concentric remodelling compared to very tall athletes. Athletes with high BMI and large BSA have the widest LV dimensions.

212 Feasibility of a novel points-based health questionnaire utilised in a nationwide cardiac screening programme for young individuals Open

Hamish MacLachlan, Robert Ambrogetti, Raghav Bhatia, Saad Fyyaz, Nikhil Chatrath , et al. · 2024

Background Widely used cardiac screening protocols in the United States and the United Kingdom include health questionnaires (HQ) with open-ended questions that require an on-site physician to differentiate between symptoms considered beni…

2 Insights into the aetiology and temporal trends in cardiac mortality in the young: a 21-year review of national and registry data in england and wales Open

Raghav Bhatia, Teo Joo Yeo, Hamish MacLachlan, Chitsa Seyani, Emmanuel Androulakis , et al. · 2024

Background An accurate representation of the incidence and aetiology of cardiac and sudden cardiac death (SCD) is vital for healthcare policymakers to effectively allocate resources for preventative strategies. Aim We aimed to report on th…

International Criteria for Reporting Study Quality for Sudden Cardiac Arrest/Death Tool Open

Jamie Edwards, C. Compton, Nikhil Chatrath, Bradley J. Petek, Aaron L. Baggish , et al. · 2024

Background Studies reporting on the incidence of sudden cardiac arrest and/or death (SCA/D) in athletes commonly lack methodological and reporting rigor, which has implications for screening and preventative policy in sport. To date, there…

Right ventricular assessment of the adolescent footballer’s heart Open

Daniel Augustine, James Willis, Sanjay Sivalokanathan, C. Wild, Alok Sharma , et al. · 2024

Introduction Athletic training can result in electrical and structural changes of the right ventricle that may mimic phenotypical features of arrhythmogenic right ventricular cardiomyopathy (ARVC), such as T-wave inversion and right heart …

Symptomatic bradyarrhythmias in the athlete—Underlying mechanisms and treatments Open

Sami Al-Othman, Mark R. Boyett, Gwilym M. Morris, Aneil Malhotra, Pietro Mesirca , et al. · 2024

Bradyarrhythmias including sinus bradycardia and atrioventricular (AV) block are frequently encountered in endurance athletes especially at night. While these are well tolerated by the young athlete, there is evidence that generally from t…

Coronary artery anomalies and the role of echocardiography in pre-participation screening of athletes: a practical guide Open

Raghav Bhatia, Jan Forster, Melanie Ackrill, Nikhil Chatrath, Gherardo Finocchiaro , et al. · 2024

The athlete’s heart: insights from echocardiography Open

H. M. Flanagan, Robert Cooper, Keith George, Daniel Augustine, Aneil Malhotra , et al. · 2023

The manifestations of the athlete’s heart can create diagnostic challenges during an echocardiographic assessment. The classifications of the morphological and functional changes induced by sport participation are often beyond ‘normal limi…

Cardiac magnetic resonance assessment of athletic myocardial fibrosis; Benign bystander or malignant marker? Open

Wasim Javed, Aneil Malhotra, Peter Swoboda · 2023

The benefits of exercise are irrefutable with a well-established dose-dependent relationship between exercise intensity and reduction in cardiovascular disease. Differentiating the physiological adaptation to exercise, termed the "athlete'…

2 Understanding cardiac and sudden death in young individuals: novel insights from the office for national statistics (ONS) in the United Kingdom Open

Raghav Bhatia, Tee Joo Yeo, Chris Miles, Steve Cox, Maite Tome , et al. · 2023

Background Previous data from the Office for National Statistics (ONS) (2002-2005) reported an incidence of sudden cardiac death (SCD) in the young of 1.8 per 100,000 per year. Aim We aimed to report on the incidence of cardiac and sudden …

Higher yield using an event-based vs. door-to-door approach for active case-finding for TB Open

Aneil Malhotra, James Mukiibi, Peter James Kitonsa, Annet Nalutaaya, Caleb Kamoga , et al. · 2023

Prevalence and diagnostic significance of de-novo 12-lead electrocardiogram patterns following covid-19 infection in elite soccer players Open

Raghav Bhatia, Aneil Malhotra, Hamish MacLachlan, Sabiha Gati, Sarandeep Marwaha , et al. · 2023

Funding Acknowledgements Type of funding sources: None. Background Considering that myocarditis is implicated in 5-15% of all exercise related sudden cardiac deaths in athletes, following a novel viral pandemic, the identification and risk…

Outcome of a nationwide screening programme in young individuals Open

H Maclachlan, Raghav Bhatia, Harshil Dhutia, Saad Fyyaz, Nikhil Chatrath , et al. · 2023

Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Cardiac Risk in the Young. Background Sudden cardiac death (SCD) seemingly affects young, healthy individuals and is therefore recognised as an important publ…

Large Region of Homozygous (ROH) Identified in Indian Patients with Autosomal Recessive Limb-Girdle Muscular Dystrophy with p.Thr182Pro Variant in SGCB Gene Open

Veena Halale Manjunath, S. G. Thenral, B. R. Lakshmi, Atchayaram Nalini, Akshi Bassi , et al. · 2023

The sarcoglycanopathies are autosomal recessive limb-girdle muscular dystrophies (LGMDs) caused by the mutations in genes encoding the α, β, γ, and δ proteins which stabilizes the sarcolemma of muscle cells. The clinical phenotype is chara…

Prevalence and diagnostic significance of de-novo 12-lead ECG changes after COVID-19 infection in elite soccer players Open

Raghav Bhatia, Aneil Malhotra, Hamish MacLachlan, Sabiha Gati, Sarandeep Marwaha , et al. · 2023

Background and aim The efficacy of pre-COVID-19 and post-COVID-19 infection 12-lead ECGs for identifying athletes with myopericarditis has never been reported. We aimed to assess the prevalence and significance of de-novo ECG changes follo…

Prevalence and diagnostic significance of novel 12-lead ECG patterns following COVID-19 infection in elite soccer players Open

Raghav Bhatia, Aneil Malhotra, Hamish MacLachlan, Sabiha Gati, A Kasiakogias , et al. · 2022

Background Identification of athletes with cardiac inflammation following COVID-19 can prevent exercise fatalities. The efficacy of pre and post COVID-19 infection electrocardiograms (ECGs) for detecting athletes with myopericarditis has n…

A Prevalence and diagnostic significance of novel 12-lead ECG patterns following COVID-19 infection in elite soccer players Open

Raghav Bhatia, Aneil Malhotra, Hamish MacLachlan, Sabiha Gati, Alexandros Kasiakogias , et al. · 2022

Background Identification of athletes with cardiac inflammation following COVID-19 can prevent exercise fatalities. The efficacy of pre and post COVID-19 infection electrocardiograms (ECGs) for detecting athletes with myopericarditis has n…

2 Prevalence and diagnostic significance of novel 12-lead ecg patterns following COVID-19 infection in elite soccer players Open

Raghav Bhatia, Aneil Malhotra, Hamish MacLachlan, Sabiha Gati, Sarandeep Marwaha , et al. · 2022

Background Identification of athletes with cardiac inflammation following COVID-19 can prevent exercise fatalities. The efficacy of pre and post COVID-19 infection electrocardiograms (ECGs) for detecting athletes with myopericarditis has n…

C Outcomes of a nationwide cardiac screening programme in young individuals Open

Hamish MacLachlan, Raghav Bhatia, Harshil Dhutia, Saad Fyazz, Nikhil Chatrath , et al. · 2022

Background There is limited information on the impact of screening for conditions associated with sudden cardiac arrest (SCA) and sudden cardiac death (SCD) in young individuals, outside the context of elite sport. We sought to determine t…

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