Rajan Kapoor
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View article: Impact-CML: Indian multicentric data supporting safe pregnancy and molecular control in women with chronic myeloid leukemia
Impact-CML: Indian multicentric data supporting safe pregnancy and molecular control in women with chronic myeloid leukemia Open
Introduction Data guiding management of tyrosine kinase inhibitors (TKI) during pregnancy in chronic myeloid leukemia (CML) are limited, especially from low- and middle-income countries (LMICs). This study was performed to describe real wo…
View article: Tali-cel is a safe and effective therapy in patients with Relapsed/Refractory B-cell non-Hodgkin lymphoma that allows equitable access- a real-world experience from India.
Tali-cel is a safe and effective therapy in patients with Relapsed/Refractory B-cell non-Hodgkin lymphoma that allows equitable access- a real-world experience from India. Open
Background : Talicabtagene autoleucel (Tali-cel), a second-generation, humanized CAR-T cell therapy targeting CD19, was approved in India in October 2023 for the treatment of relapsed or refractory (r/r) B-cell malignancies. This report pr…
View article: Avifaunal Diversity in Relation to Trophic Guilds at Open Grain Storage Facilities of Punjab
Avifaunal Diversity in Relation to Trophic Guilds at Open Grain Storage Facilities of Punjab Open
The study revealed 25 bird species at grain storage facilities under different storage conditions and a total of five trophic guilds, i.e., granivorous, insectivorous, carnivorous, nectarivorous, and omnivorous, were recorded. Granivorous …
View article: Patterns of Care and Outcomes of Adults ≥ 40 Years of Age with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL): A Multicenter Registry Analysis from India
Patterns of Care and Outcomes of Adults ≥ 40 Years of Age with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL): A Multicenter Registry Analysis from India Open
Introduction: Survival outcomes in adults aged ≥ 40 years with acute lymphoblastic leukemia (ALL) are dismal at around 30% in clinical trial settings. Limited information exists on the outcomes and patterns of care in developing countries …
View article: Human Leukocyte Antigen-DR and Cluster Designation 34: Double-negative Acute Myeloid Leukemias – Our Experience in Clinical Setting
Human Leukocyte Antigen-DR and Cluster Designation 34: Double-negative Acute Myeloid Leukemias – Our Experience in Clinical Setting Open
Introduction: Dual negativity for cluster designation (CD) 34 and human leukocyte antigen (HLA)-DR antigen in leukemia panel is an important finding in clinical practice. The combination of this finding though seen classically in acute pro…
View article: Treatment challenges and outcomes of older patients with acute myeloid leukemia from India
Treatment challenges and outcomes of older patients with acute myeloid leukemia from India Open
Globally, overall survival (OS) of older patients with AML continues to be suboptimal with very little data from India. In a multicenter registry analysis, we evaluated 712 patients with AML older than 55 years. Only 323 (45.3%) underwent …
View article: Identification of Factors Influencing Donor‐Derived Cell‐Free DNA Levels up to One Year After Kidney Transplant
Identification of Factors Influencing Donor‐Derived Cell‐Free DNA Levels up to One Year After Kidney Transplant Open
Introduction: Donor‐derived cell‐free DNA (dd‐cfDNA) in the peripheral blood of allograft recipients has shown to early identify allograft injury. In this study, we assessed the factors that influence the amount of circulating dd‐cfDNA dur…
View article: Outcomes of Philadelphia Chromosome (Ph) Positive Acute Lymphoblastic Leukemia: An Indian Multi-Institution, Prospective Study from the Haematology Cancer Consortium (HCC)
Outcomes of Philadelphia Chromosome (Ph) Positive Acute Lymphoblastic Leukemia: An Indian Multi-Institution, Prospective Study from the Haematology Cancer Consortium (HCC) Open
Introduction One of the commonest genetic abnormalities seen in adult Acute Lymphoblastic Leukemia (ALL) is the reciprocal translocation between chromosomes (Chr.) 9 and 22, leading to the formation of the BCR-ABL fusion gene. This manifes…
View article: An observational study of comorbidities and their outcome in patients with COVID-19 admitted to a tertiary care hospital
An observational study of comorbidities and their outcome in patients with COVID-19 admitted to a tertiary care hospital Open
Background : The coronavirus disease (COVID-19) has devastating pervasiveness throughout the world. Moreover, the presence of comorbidities could worsen the effects of COVID-19. Therefore, our aim was to study the types of comorbidities in…
View article: Depredatory Birds and their Management in Open Grain Storage Facilities of Punjab
Depredatory Birds and their Management in Open Grain Storage Facilities of Punjab Open
This study evaluates the relative abundance of depredatory birds and their management in open grain storage facilities of Punjab. Maximum relative abundance of blue rock pigeon observed. This is due to food availability and it is the major…
View article: Clinico-laboratory Profile and Outcomes of Megaloblastic Anemia presenting as Severe Pyrexial Illness mimicking Tropical Infection
Clinico-laboratory Profile and Outcomes of Megaloblastic Anemia presenting as Severe Pyrexial Illness mimicking Tropical Infection Open
Background: Anemia-causing fever has been described in patients with megaloblastic anemia. Although the exact mechanism of this is unknown, high-grade fever is relatively less reported. Materials and methods: This prospective observational…
View article: Outcomes of near-miss/adverse perioperative events during elective and emergency non-cardiac surgeries that required unplanned admissions to the intensive care unit of a tertiary care center: a retrospective cohort study
Outcomes of near-miss/adverse perioperative events during elective and emergency non-cardiac surgeries that required unplanned admissions to the intensive care unit of a tertiary care center: a retrospective cohort study Open
Background The near-miss/adverse events during elective and emergency non-cardiac surgeries requiring unplanned admissions to the intensive care unit (ICU) during the perioperative period are not known. Patients undergoing elective and eme…
View article: 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan Findings in a Rare Case of Subcutaneous Panniculitis-Like T-Cell Lymphoma.
18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan Findings in a Rare Case of Subcutaneous Panniculitis-Like T-Cell Lymphoma. Open
Skin lymphomas are less common and subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a fairly rare subtype of primary cutaneous lymphoma. Skin lymphomas involve subcutaneous adipose tissues with no involvement of lymph nodes. Diagn…
View article: Case-based Roundtable on Management Approach for Newly Diagnosed Chronic Myeloid Leukaemia (CML) Patients
Case-based Roundtable on Management Approach for Newly Diagnosed Chronic Myeloid Leukaemia (CML) Patients Open
Chronic myeloid leukaemia (CML) is one of the success stories in oncology care. The remarkable activity of tyrosine kinase inhibitors (TKIs) in CML has revolutionised the therapeutic landscape of this cancer which was uniformly fatal till …
View article: Cancer in the Adolescent and Young Adults (AYA) and Children: A Comprehensive Analysis of the Epidemiology and Psychosocial Morbidity in the Indian Population
Cancer in the Adolescent and Young Adults (AYA) and Children: A Comprehensive Analysis of the Epidemiology and Psychosocial Morbidity in the Indian Population Open
Aims Adolescent and young adults (AYAs), children with cancer, and their guardians have unique psychosocial morbidities adversely effecting quality of life (QOL). This is measurable using patented tools. We analyzed epidemiological and cli…