Explanipedia

Predictions of postoperative and perioperative complications of laparoscopic cholecystectomy using machine learning algorithms: systematic review Open

Shahzeb Leghari, Muhammad Tausif, Rajan Rehan, Wajiha Ikram · 2025

Intravascular Lithotripsy-Enabled Transcatheter Aortic Valve Replacement in Heavily Calcified Bicuspid Aortic Valve Open

Rajan Rehan, Alexandra Moss, James Cotton, Benjamin Wrigley, Shahzad Munir , et al. · 2025

IVL may enhance lesion preparation in heavily calcified BAVs undergoing TAVR. Dedicated IVL devices for structural interventions are an emerging need.

SEC61B regulates calcium flux and platelet hyperreactivity in diabetes Open

Yvonne Kong, Rajan Rehan, Cesar L. Moreno, S. Madsen, Yunwei Zhang , et al. · 2025

Platelet hyperreactivity increases the risk of cardiovascular thrombosis in diabetes and failure of antiplatelet drug therapies. Elevated basal and agonist-induced calcium flux is a fundamental cause of platelet hyperreactivity in diabetes…

Impact of Nitroglycerin Administration on Acetylcholine Provocation Testing in Angina With Nonobstructive Coronary Arteries Open

Rajan Rehan, Christopher Wong, James Weaver, Pankaj Jain, Mark Adams , et al. · 2025

Nitroglycerin administration reduces the diagnostic accuracy of ACh provocation testing for CAS in angina with nonobstructive coronary arteries patients. Findings from this study indicate that clinicians should avoid NTG administration pri…

Functional Coronary Angiography for the Diagnosis of Coronary Vasomotor Disorders Open

Thomas J. Ford, C. Zeitz, J. Spiro, A. Yong, Jamie Layland , et al. · 2025

Microvascular and/or vasospastic angina are two common forms of coronary vasomotor disorders that may occur in patients with ischaemia and non-obstructed coronary arteries (INOCA) or myocardial infarction with non-obstructive coronary arte…

An updated review on therapeutic strategies in coronary microvascular dysfunction Open

Chinmay Khandkar, Rajan Rehan, J. Ravindran, A. Yong · 2025

Coronary microvascular dysfunction (CMD) is well-known cause of angina, yet treatment options remain limited. This systematic review and meta-analysis examines the current literature and provides a contemporary evaluation of treatments usi…

Role of Ultrasound-Based Therapies in Cardiovascular Diseases Open

Amit Bansal, Bernard Bulwer, Ricarda von Krüchten, Jagkirat Singh, Rajan Rehan , et al. · 2024

Intracoronary thrombolysis in ST-elevation myocardial infarction: a systematic review and meta-analysis Open

Rajan Rehan, Sohaib Virk, Christopher Wong, Freda Passam, Jamie Layland , et al. · 2024

Background Despite restoration of epicardial blood flow in acute ST-elevation myocardial infarction (STEMI), inadequate microcirculatory perfusion is common and portends a poor prognosis. Intracoronary (IC) thrombolytic therapy can reduce …

Prevalence of Coronary Vasomotor Disorders in Patients With Angina and Nonobstructive Coronary Arteries: A Sydney Experience Open

Rajan Rehan, Christopher Wong, C. David Cooke, James Weaver, Pankaj Jain , et al. · 2024

Coronary vasomotor disorders are highly prevalent among ANOCA patients. This study highlights the importance of increasing national awareness and the use of functional coronary angiography to evaluate and manage this unique cohort.

Usefulness of temporary pacemaker during acetylcholine provocation testing Open

Rajan Rehan, Christopher C Y Wong, James B. Weaver, Pankaj Jain, Mark Adams , et al. · 2024

Multivessel Coronary Function Testing Increases Diagnostic Yield in Patients With Angina and Nonobstructive Coronary Arteries Open

Rajan Rehan, Christopher Wong, James Weaver, William Chan, Jennifer A. Tremmel , et al. · 2024

Multivessel CFT resulted in an increased diagnostic yield in patients with ANOCA compared with single-vessel testing. The results of this study suggest that multivessel CFT has a role in the management of patients with ANOCA.

Identification of SEC61B as a novel regulator of calcium flux and platelet hyperreactivity in diabetes mellitus Open

Yvonne Kong, Rajan Rehan, Cesar L. Moreno, Søren Madsen, Yunwei Zhang , et al. · 2024

High platelet reactivity is associated with adverse clinical events and is more frequent in people with diabetes mellitus (DM). To better understand platelet dysfunction in DM, we performed a proteomic analysis in platelets from a matched …

PB0861 Endoplasmic Reticulum (ER) Stress is Increased in Diabetic Platelets and Contributes to Platelet Hyperactivity Open

Yuan Kong, Rajan Rehan, F Ghani, James C. Fenwick, David Robertshaw , et al. · 2023

Background: Wound healing is a multi-step process involving different cell types and growth factors.Though platelet-rich plasma has been used to accelerate wound repair, functional understanding of how platelet functions affect wound heali…

Insights into the invasive diagnostic challenges of coronary artery vasospasm – A systematic review Open

Rajan Rehan, John F. Beltrame, A. Yong · 2023

Therapeutic Utility of Functional Angiography in INOCA Open

Rajan Rehan, Chun‐Ka Wong, James Weaver, M. Ng, A. Yong · 2023

The INOCA Clinic: An Initial Australia Experience Open

Rajan Rehan, C. David Cooke, A. Yong, M. Ng · 2023

Coronary Artery Volume/Myocardial Mass Ratio, Epicardial and Pericoronary Adipose Tissue Volume Assessed on Computed Tomography Coronary Angiography is Associated With Index of Microcirculatory Resistance (IMR) Open

R. Hii, Kevin Cheng, J. O’Brien, Rajan Rehan, J. Ravindran , et al. · 2023

Multi-Vessel Functional Angiography Increases Diagnostic Yield in INOCA Open

Rajan Rehan, Christopher Wong, James Weaver, M. Ng, A. Yong · 2023

This abstract has been withdrawn Open

Rajan Rehan, Christopher Wong, James Weaver, M. Ng, A. Yong · 2023

Utility of Temporary Pacemaker During Acetylcholine Provocation Testing Open

Rajan Rehan, Chun‐Ka Wong, James Weaver, M. Ng, A. Yong · 2023

This abstract has been withdrawn Open

Rachael Hii, Kevin Cheng, J. O’Brien, Rajan Rehan, J. Ravindran , et al. · 2023

This abstract has been withdrawn Open

Rajan Rehan, C. David Cooke, A. Yong, M. Ng · 2023

This abstract has been withdrawn Open

Rajan Rehan, Christopher Wong, James Weaver, M. Ng, A. Yong · 2023

Coronary microvascular dysfunction: A review of recent progress and clinical implications Open

Rajan Rehan, A. Yong, M. Ng, James Weaver, Rajesh Puranik · 2023

The coronary microcirculation plays a cardinal role in regulating coronary blood flow to meet the changing metabolic demands of the myocardium. Coronary microvascular dysfunction (CMD) refers to structural and functional remodeling of the …

Coronary Vasospastic Angina: A Review of the Pathogenesis, Diagnosis, and Management Open

Rajan Rehan, James Weaver, A. Yong · 2022

Vasospastic angina (VSA) is an under-appreciated cause of chest pain. It is characterised by transient vasoconstriction of the coronary arteries and plays a significant role in the pathogenesis of stable angina and acute coronary syndromes…

Coronary vessel segmentation using multiresolution and multiscale deep learning Open

Zhengqiang Jiang, Chubin Ou, Yi Qian, Rajan Rehan, A. Yong · 2021

We present a coronary vessel segmentation method for X-Ray coronary angiography images using multiresolution and multiscale deep learning. Our segmentation method constructs a set of multiresolution images from an input image via bilinear …

Adult Congenital Heart Disease Survivors at Age 50 Years: Medical and Psychosocial Status Open

Rajan Rehan, Irina Kotchetkova, Rachael Cordina, David S. Celermajer · 2020

Plasma microRNAs in human left ventricular reverse remodelling Open

Rajan Rehan, Sanjay Patel · 2020

859 Outcomes for High-Risk Percutaneous Coronary Intervention (PCI) in Patients Referred from a Rural Centre to Metropolitan Sites Open

Rajan Rehan, Elise Kempler, K. McMaster, G. Larnach, D. Amos , et al. · 2020

Efax STEMI Study. Accuracy of Interpreting Fax to Email ST-elevation Myocardial Infarction Electrocardiograms Viewed on Smartphones Open

Elias Nehme, John Riskallah, Rajan Rehan, Peter Fahmy, D. Burgess , et al. · 2016

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