Rajdeep Guha
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View article: Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents
Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents Open
In this study, a series of novel α, β-unsaturated carbonyl compounds (3a-j) and their pyrazoline derivatives (4a-e and 5a-b) were designed and successfully synthesized. All synthesized compounds were characterized using various spectroscop…
View article: Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol
Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol Open
View article: Mitochondrial calcium uniporter regulates human fibroblast-like synoviocytes invasion via altering mitochondrial dynamics and dictates rheumatoid arthritis pathogenesis
Mitochondrial calcium uniporter regulates human fibroblast-like synoviocytes invasion via altering mitochondrial dynamics and dictates rheumatoid arthritis pathogenesis Open
Rheumatoid arthritis (RA) is characterized by the aggressive migration and invasion of fibroblast-like synoviocytes (FLS) into cartilage and bone, a process that is significantly influenced by mitochondrial calcium uptake. This study highl…
View article: ORMDL3 regulates NLRP3 inflammasome activation by maintaining ER-mitochondria contacts in human macrophages and dictates ulcerative colitis patient outcome
ORMDL3 regulates NLRP3 inflammasome activation by maintaining ER-mitochondria contacts in human macrophages and dictates ulcerative colitis patient outcome Open
View article: Oral Administration of a specific p300/CBP Lysine Acetyltransferase Activator Induces Synaptic Plasticity and Repairing Spinal Cord Injury
Oral Administration of a specific p300/CBP Lysine Acetyltransferase Activator Induces Synaptic Plasticity and Repairing Spinal Cord Injury Open
TTK21 is a small molecule activator of p300/CBP acetyltransferase activity, which upon conjugation with glucose-derived carbon nanosphere (CSP) can efficiently cross the blood-brain barrier and activate histone acetylation in the brain. It…
View article: CCDC 1969185: Experimental Crystal Structure Determination
CCDC 1969185: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Infectivity, virulence, pathogenicity, host-pathogen interactions of SARS and SARS-CoV-2 in experimental animals: a systematic review
Infectivity, virulence, pathogenicity, host-pathogen interactions of SARS and SARS-CoV-2 in experimental animals: a systematic review Open
View article: Pirfenidone inhibits post-traumatic proliferative vitreoretinopathy
Pirfenidone inhibits post-traumatic proliferative vitreoretinopathy Open
View article: Intravitreal pirfenidone inhibits post traumatic proliferative vitreoretinopathy
Intravitreal pirfenidone inhibits post traumatic proliferative vitreoretinopathy Open
View article: Molecular cues to the anti-implantation effect of nano-puerarin in rats
Molecular cues to the anti-implantation effect of nano-puerarin in rats Open
Puerarin, a selective oestrogen receptor modulator, intercepts implantation in rats, albeit at unacceptably higher doses. We developed poly lactic-co-glycolic acid-encapsulated nano-puerarin (PN) and mapped the molecular pathway underlying…
View article: Non-mulberry Silk Fibroin Biomaterial for Corneal Regeneration
Non-mulberry Silk Fibroin Biomaterial for Corneal Regeneration Open