Rajeev Chaudhary
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View article: Surgical periosteal resection changes bone geometry and strength in New Zealand white rabbits
Surgical periosteal resection changes bone geometry and strength in New Zealand white rabbits Open
Multiple pediatric neuromuscular conditions can result in thin and gracile long bone formation with increased risk of pathologic fracture. Following previous observations, we sought to characterize structural changes after periosteal resec…
View article: Second-harmonic generation microscopy analysis reveals proteoglycan decorin is necessary for proper collagen organization in prostate
Second-harmonic generation microscopy analysis reveals proteoglycan decorin is necessary for proper collagen organization in prostate Open
Collagen remodeling occurs in many prostate pathologies; however, the underlying structural architecture in both normal and diseased prostatic tissues is largely unexplored. Here, we use second-harmonic generation (SHG) microscopy to speci…
View article: Polarization-resolved second harmonic generation imaging of human ovarian cancer
Polarization-resolved second harmonic generation imaging of human ovarian cancer Open
Remodeling of the extracellular matrix in human ovarian cancer can be manifested in increased collagen concentration, changes in alignment within fibrils/fibers and/or up-regulation of different collagen isoforms. We used pixel-based secon…
View article: Accuracy of model-based tracking of knee kinematics and cartilage contact measured by dynamic volumetric MRI
Accuracy of model-based tracking of knee kinematics and cartilage contact measured by dynamic volumetric MRI Open
View article: Periosteal Fiber Transection During Periosteal Procedures Is Crucial to Accelerate Growth in the Rabbit Model
Periosteal Fiber Transection During Periosteal Procedures Is Crucial to Accelerate Growth in the Rabbit Model Open
These findings in an animal model support previous claims that limb overgrowth occurs as the result of periosteal disruption. Based on these findings in rabbits, we believe that less invasive procedures like periosteal transection are a pr…
View article: Multicomponent <i>T</i><sub>2</sub> analysis of articular cartilage with synovial fluid partial volume correction
Multicomponent <i>T</i><sub>2</sub> analysis of articular cartilage with synovial fluid partial volume correction Open
Purpose To investigate the use of a three‐pool model to account for the confounding effects of synovial fluid on multicomponent T 2 analysis of articular cartilage using Multicomponent Driven Equilibrium Single Shot Observation of T 1 and …
View article: Articular cartilage zonal differentiation via 3D Second-Harmonic Generation imaging microscopy
Articular cartilage zonal differentiation via 3D Second-Harmonic Generation imaging microscopy Open
Collectively, these results provide quantitative measurements of structural changes at both the fiber and fibril assembly of the different cartilage zones and reveals structural information not possible by other microscope modalities. This…