Rajitha Panonnummal
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View article: Molecular Markers of Endothelial Dysfunction in Post-COVID Prediabetes: A Focus on NOS3 Gene Expression and Pro-Inflammatory Cytokine Profiles
Molecular Markers of Endothelial Dysfunction in Post-COVID Prediabetes: A Focus on NOS3 Gene Expression and Pro-Inflammatory Cytokine Profiles Open
Background: Prediabetes, marked by early insulin resistance and chronic low-grade inflammation, is closely linked to endothelial dysfunction and increased cardiovascular risk. Post-COVID-19 recovery may intensify this risk due to persisten…
View article: Exosomes isolated from citrus lemon: a promising candidate for the treatment of Alzheimer's disease
Exosomes isolated from citrus lemon: a promising candidate for the treatment of Alzheimer's disease Open
Aim: To investigate the efficacy of exosome-like nanovesicles from citrus lemon (EXO-CLs) in combating oxidative stress associated with Alzheimer's disease.Materials & methods: EXO-CLs were isolated through differential ultra…
View article: Targeting Viral ORF3a Protein: A New Approach to Mitigate COVID-19 Induced Immune Cell Apoptosis and Associated Respiratory Complications
Targeting Viral ORF3a Protein: A New Approach to Mitigate COVID-19 Induced Immune Cell Apoptosis and Associated Respiratory Complications Open
Infection with SARS-CoV-2 is a growing concern to the global well-being of the public at present. Different amino acid mutations alter the biological and epidemiological characteristics, as well as immune resistance of SARS-CoV-2. The viru…
View article: ‘Magnesium’-the master cation-as a drug—possibilities and evidences
‘Magnesium’-the master cation-as a drug—possibilities and evidences Open
View article: Ethosomal Gel Formulation of Alpha Phellandrene for the Transdermal Delivery in Gout
Ethosomal Gel Formulation of Alpha Phellandrene for the Transdermal Delivery in Gout Open
Purpose: Purpose was to improve the skin compatibility and permeability of alpha phellandrene through an ethosomal gel formulation for the treatment of gout; as the oral use of the drug is reported to cause gastrointestinal d…
View article: A Review on Newer Ocular Drug Delivery Systems with an Emphasis on Glaucoma
A Review on Newer Ocular Drug Delivery Systems with an Emphasis on Glaucoma Open
Glaucoma is an irreversible condition resulting from the increase in intraocular pressure (IOP); which leads to permanent loss of vision with the destruction of retinal ganglion cells (RGCs). The IOP elevations are controlled in normal by …
View article: ANTI-INFLAMMATORY ACTIVITY OF HMG CO A REDUCTASE INHIBITORS: A COMPARATIVE STUDY
ANTI-INFLAMMATORY ACTIVITY OF HMG CO A REDUCTASE INHIBITORS: A COMPARATIVE STUDY Open
Objective: The purpose of the present study was to reveal the potential pleotropic anti-inflammatory activity of two hmg-co Reductase inhibitors, Rosuvastatin and atorvastatin in comparison with standard drug diclofenac. Methods: The m…