Rajiv Nathoo
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View article: Necrobiosis lipoidica arising in a port wine stain treated with topical ruxolitinib
Necrobiosis lipoidica arising in a port wine stain treated with topical ruxolitinib Open
We present a unique case of necrobiosis lipoidica (NL) arising within a port-wine stain (PWS), which, to our knowledge, has not been previously reported. NL is a rare granulomatous disorder often associated with diabetes mellitus, characte…
View article: An unusual chest lesion with dual pathologies
An unusual chest lesion with dual pathologies Open
Granuloma faciale (GF) is a rare, benign, chronic inflammatory condition characterized by well-defined reddish-brown papules, nodules, or plaques, often demonstrating follicular accentuation and telangiectasia, which may be termed “peau d’…
View article: Retinoids for the Treatment of Refractory Grover’s Disease: A Case Series and Review of the Literature
Retinoids for the Treatment of Refractory Grover’s Disease: A Case Series and Review of the Literature Open
Grover's disease, also known as transient acantholytic dermatosis (TAD), currently has no published randomized control trials regarding the treatment of the disease; thus, evidence for treatment is largely derived from case studies and cas…
View article: Case Report of Leprosy in Central Florida, USA, 2022
Case Report of Leprosy in Central Florida, USA, 2022 Open
Florida, USA, has witnessed an increased incidence of leprosy cases lacking traditional risk factors. Those trends, in addition to decreasing diagnoses in foreign-born persons, contribute to rising evidence that leprosy has become endemic …
View article: Photodistributed Lichenoid Eruption with Alopecia: A Unique Presentation of Graham–Little–Piccardi–Lasseur Syndrome
Photodistributed Lichenoid Eruption with Alopecia: A Unique Presentation of Graham–Little–Piccardi–Lasseur Syndrome Open
Graham–Little–Piccardi–Lasseur syndrome (GLPLS) is characterized by diffuse alopecia and a lichenoid follicular eruption affecting the scalp, eyebrows, and intertriginous regions. It is considered a variant of lichen planopilaris. The cond…
View article: An Updated Review of the Therapeutic Management of Keratoacanthomas.
An Updated Review of the Therapeutic Management of Keratoacanthomas. Open
Although surgical removal with excision or Mohs micrographic surgery remains the standard of therapy, there are many alternative therapeutic modalities that can be utilized.
View article: Superficial solitary fibrous tumor masquerading as a dermoid cyst: a case report
Superficial solitary fibrous tumor masquerading as a dermoid cyst: a case report Open
BACKGROUND: Solitary fibrous tumors (SFTs) are relatively rare spindle cell neoplasms uncommonly seen in dermatology practice. Initially discovered as a pleural tumor, SFTs have also been found in extra-pleural sites including the skin and…
View article: Impaired calcium signalling and neuropsychiatric disorders in Darier disease: An exploratory review
Impaired calcium signalling and neuropsychiatric disorders in Darier disease: An exploratory review Open
Darier (Darier‐White) disease (DD) is an autosomal dominant skin disorder caused by pathogenic mutations in the ATP2A2 gene which encodes a calcium ATPase in the sarco‐endoplasmic reticulum (SERCA2). Defects in the SERCA2 protein lead to a…
View article: Vaccines and dermatology: Expanding the role of dermatology clinics in the name of public health
Vaccines and dermatology: Expanding the role of dermatology clinics in the name of public health Open
Vaccine hesitancy is common and increasingly relevant in the current medical landscape. Several factors provide dermatology practices a unique opportunity to play a role in addressing vaccine resistance through improving education and oppo…
View article: Expanding the spectrum of epidermolysis bullosa simplex: Syndromic epidermolysis bullosa simplex with nephropathy and epilepsy secondary to CD151 tetraspanin defect—a case report and review of the literature
Expanding the spectrum of epidermolysis bullosa simplex: Syndromic epidermolysis bullosa simplex with nephropathy and epilepsy secondary to CD151 tetraspanin defect—a case report and review of the literature Open
Heritable forms of epidermolysis bullosa (EB) are considered the prototype of genetic skin fragility disorders.1 Classically, EB is divided into 4 types on the basis of the location of the dermoepidermal junction in relation to the basemen…
View article: Multiple Indolent Asymptomatic Yellow-Orange Patches and Plaques
Multiple Indolent Asymptomatic Yellow-Orange Patches and Plaques Open
An 83-year-old Caucasian male presented with a history of asymptomatic yellow-orange macules and plaques concentrated on his trunk and proximal extremities that have been slowly progressing for the past three years. A punch biopsy revealed…
View article: Isolated Nail Pigmentation Induced by Minocycline: A Case Report
Isolated Nail Pigmentation Induced by Minocycline: A Case Report Open
Isolated pigmentation of the nails induced by minocycline therapy is an uncommon occurrence that has only been reported in a handful of cases. In the reported cases of isolated nail discoloration, it has been suggested that nail discolorat…
View article: Recurrent Drug-Induced Hypersensitivity Syndrome Following Bortezomib for Multiple Myeloma
Recurrent Drug-Induced Hypersensitivity Syndrome Following Bortezomib for Multiple Myeloma Open
Drug-induced hypersensitivity syndrome is a rare, severe, and delayed hypersensitivity reaction that may occur with exposure to a number of medications. Typical implicated medications include aromatic anticonvulsants, sulfonamides, minocyc…
View article: Recurrent Erythema Multiforme Induced by the Combination of Pembrolizumab and Radiation
Recurrent Erythema Multiforme Induced by the Combination of Pembrolizumab and Radiation Open
Erythema multiforme is a self-limited condition that is characterized by the rapid onset of symmetric targetoid lesions. This hypersensitivity reaction is commonly triggered by herpes simplex virus and Mycoplasma pneumoniae infections. Pem…
View article: Dermoscopy of Inflammatory Linear Verrucous Epidermal Nevus: Brown and Red Glomerular Structures Over a White Background as an Identifying Feature
Dermoscopy of Inflammatory Linear Verrucous Epidermal Nevus: Brown and Red Glomerular Structures Over a White Background as an Identifying Feature Open
Inflammatory linear verrucous epidermal nevus (ILVEN) is an uncommon variant of keratinocytic epidermal nevus that typically presents as linear erythematous and verrucous papules which often coalesce into plaques. ILVEN is characteristical…
View article: Scabies Associated with Granulomatous Dermatitis
Scabies Associated with Granulomatous Dermatitis Open
Scabies is a relatively common parasitic infection, which has sometimes been associated with the formation of granuloma annulare. We report the case of an 86-year-old female who developed a non-necrotizing granulomatous dermatitis after a …
View article: Comparing the efficacies of alginate, foam, hydrocolloid, hydrofiber, and hydrogel dressings in the management of diabetic foot ulcers and venous leg ulcers: a systematic review and meta-analysis examining how to dress for success
Comparing the efficacies of alginate, foam, hydrocolloid, hydrofiber, and hydrogel dressings in the management of diabetic foot ulcers and venous leg ulcers: a systematic review and meta-analysis examining how to dress for success Open
Diabetic foot ulcers and venous leg ulcers are chronic wounds frequently encountered by dermatologists. Choosing appropriate wound dressings can effectively promote wound healing and potentially reduce morbidity and financial burden experi…