Rajive Kumar
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View article: Can height and weight of the patient predict the tibial footprint dimensions of anterior cruciate ligament on MRI: an observational study
Can height and weight of the patient predict the tibial footprint dimensions of anterior cruciate ligament on MRI: an observational study Open
Background: Anterior cruciate ligament (ACL) reconstruction techniques are increasingly individualized based on patient-specific anatomy. Preoperative knowledge of ACL dimensions guides surgical planning, particularly regarding single vers…
View article: Isolated cutaneous metastasis from esophageal squamous cell carcinoma: A comprehensive case report and review
Isolated cutaneous metastasis from esophageal squamous cell carcinoma: A comprehensive case report and review Open
Background Cutaneous metastases from internal malignancies constitute 0.5% to 9% of all metastatic cancers, with lung, breast, and colorectal cancers being the most common primary sites. Objective Esophageal squamous cell carcinoma (ESCC) …
View article: Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature
Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature Open
Background: Colon cancer is uncommon in children. This article reports a case of signet ring cell carcinoma in an 11-year-old child who presented with acute intestinal obstruction. Case report: An 11-year-old boy presented with progressive…
View article: Refinement of Risk-Stratification of Cytogenetically Normal Acute Myeloid Leukemia Adult Patients by MN1 Expression
Refinement of Risk-Stratification of Cytogenetically Normal Acute Myeloid Leukemia Adult Patients by MN1 Expression Open
MN1 expression is an independent predictor of outcome in CN-AML.
View article: Decoding the genetic symphony: Profiling protein-coding and long noncoding RNA expression in T-acute lymphoblastic leukemia for clinical insights
Decoding the genetic symphony: Profiling protein-coding and long noncoding RNA expression in T-acute lymphoblastic leukemia for clinical insights Open
T-acute lymphoblastic leukemia (T-ALL) is a heterogeneous malignancy characterized by the abnormal proliferation of immature T-cell precursors. Despite advances in immunophenotypic classification, understanding the molecular landscape and …
View article: Data from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma
Data from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma Open
Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiation and chemotherapy. Current therapies for RCC patients are inefficient due to the lack of diagnostic and therapeutic markers. Our recent studies have suggest…
View article: Supplementary Information from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma
Supplementary Information from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma Open
Supplementary Information from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma
View article: Supplementary Information from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma
Supplementary Information from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma Open
Supplementary Information from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma
View article: Data from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma
Data from Sperm-Associated Antigen 9 Is Associated With Tumor Growth, Migration, and Invasion in Renal Cell Carcinoma Open
Renal cell carcinoma (RCC) represents one of the most resistant tumors to radiation and chemotherapy. Current therapies for RCC patients are inefficient due to the lack of diagnostic and therapeutic markers. Our recent studies have suggest…
View article: Unilateral sacral erector spinae plane block for lower limb surgery in children
Unilateral sacral erector spinae plane block for lower limb surgery in children Open
Summary The erector spinae plane block is a versatile regional anaesthesia technique used for a variety of truncal surgeries. A novel variation is the sacral erector spinae plane block which is gaining popularity for perineal and anorectal…
View article: Prognostic significance of protein-coding and long non-coding RNA expression profile in T-cell acute lymphoblastic leukemia
Prognostic significance of protein-coding and long non-coding RNA expression profile in T-cell acute lymphoblastic leukemia Open
T-acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy associated with poor outcome. To unravel gene-expression profile of immunophenotypic subtypes of T-ALL, we did transcriptome analysis in 35 cases. We also ana…
View article: Prognostic Relevance of Expression of EMP1, CASP1, and NLRP3 Genes in Pediatric B-Lineage Acute Lymphoblastic Leukemia
Prognostic Relevance of Expression of EMP1, CASP1, and NLRP3 Genes in Pediatric B-Lineage Acute Lymphoblastic Leukemia Open
Glucocorticoid (GC), such as prednisolone, is an essential component of multidrug chemotherapy regimen for pediatric acute lymphoblastic leukemia (ALL). Resistance to GC in leukemia cells is associated with disease progression and poor pro…
View article: <i>MEF2C</i> expression, but not absence of bi-allelic deletion of TCR gamma chains (ABD), is a predictor of patient outcome in Indian T-acute lymphoblastic leukemia.
<i>MEF2C</i> expression, but not absence of bi-allelic deletion of TCR gamma chains (ABD), is a predictor of patient outcome in Indian T-acute lymphoblastic leukemia. Open
Emerging evidence suggests existence of three prognostically relevant molecular entities among immature T-ALL-early thymic precursor ALL (ETP-ALL), T-ALL with the absence of biallelic deletion of TCRγ chains (ABD) and MEF2C (Myocyte Enhanc…
View article: PCL mimicking vHCL: a rare morphological variant
PCL mimicking vHCL: a rare morphological variant Open
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A 76-year-old woman presented with pallor, fatigability, and body ache. The complete blood count showed hemoglobin 6.7 g/dL, leukocytes 6.5 × 109/L, lymphocytes 5.1 × 109/L, and platelets 11 × 109/L. Peripheral blood smears …
View article: Case Report: Whole exome sequencing identifies a novel frameshift insertion c.1325dupT (p.F442fsX2) in the tyrosine kinase domain of BTK gene in a young Indian individual with X-linked agammaglobulinemia
Case Report: Whole exome sequencing identifies a novel frameshift insertion c.1325dupT (p.F442fsX2) in the tyrosine kinase domain of BTK gene in a young Indian individual with X-linked agammaglobulinemia Open
X-linked agammaglobulinemia (XLA) is an extremely rare inherited primary immunodeficiency characterized by recurrent bacterial infections, decrease in number of mature B cells and low serum immunoglobulins. XLA is caused by mutations in th…
View article: Case Report: Whole exome sequencing identifies a novel frameshift insertion c.1325dupT (p.F442fsX2) in the tyrosine kinase domain of BTK gene in a young Indian individual with X-linked agammaglobulinemia
Case Report: Whole exome sequencing identifies a novel frameshift insertion c.1325dupT (p.F442fsX2) in the tyrosine kinase domain of BTK gene in a young Indian individual with X-linked agammaglobulinemia Open
X-linked agammaglobulinemia (XLA) is an extremely rare inherited primary immunodeficiency characterized by recurrent bacterial infections, decrease in number of mature B cells and low serum immunoglobulins. XLA is caused by mutations in th…
View article: Nucleophosmin mutation analysis in acute myeloid leukaemia
Nucleophosmin mutation analysis in acute myeloid leukaemia Open
Background & objectives: Mutation of nucleophosmin ( NPM1 ) gene in the absence of FLT3-ITD (FMS related tyrosine kinase 3 - internal tandem duplications) mutation carries a good prognosis in cytogenetically normal acute myeloid leukaemia …
View article: A novel cancer testis antigen target A-kinase anchor protein (AKAP4) for the early diagnosis and immunotherapy of colon cancer
A novel cancer testis antigen target A-kinase anchor protein (AKAP4) for the early diagnosis and immunotherapy of colon cancer Open
Colorectal cancer (CRC) is mainly a disease of developed countries and a major cause of death worldwide. The present study was undertaken to investigate the association of novel cancer testis (CT) antigen, A-kinase anchor protein (AKAP4) w…
View article: Additional file 4: Figure S3. of Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer
Additional file 4: Figure S3. of Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer Open
HSP70-2 knockdown initiates apoptosis in breast cancer cells. (PPTX 2620 kb)
View article: Additional file 1: of Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer
Additional file 1: of Heat shock protein 70-2 (HSP70-2) overexpression in breast cancer Open
Supplementary Methods, Supplementary table, Supplementary Figure Legends. (DOCX 41 kb)