Rajkumar Krishnan
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View article: Comparative Evaluation of Surface Hardness, Roughness, Tensile Strength, and Antifungal Property of Soft Liners Incorporated With Silver Vanadate and Titanium Dioxide Nanoparticles: An In Vitro Study
Comparative Evaluation of Surface Hardness, Roughness, Tensile Strength, and Antifungal Property of Soft Liners Incorporated With Silver Vanadate and Titanium Dioxide Nanoparticles: An In Vitro Study Open
Aim This in vitro study aimed to evaluate and compare the antifungal efficacy, surface hardness, roughness, and tensile bond strength of heat-cure acrylic resin with soft liners incorporated with silver vanadate and titanium dioxide nanopa…
View article: Comparative Evaluation of the Shear Bond Strength of Self-Adhesive and Glass Ionomer Cement to Dentin After Removal of Hemostatic Agents Using Different Cleansing Protocols: An In Vitro Study
Comparative Evaluation of the Shear Bond Strength of Self-Adhesive and Glass Ionomer Cement to Dentin After Removal of Hemostatic Agents Using Different Cleansing Protocols: An In Vitro Study Open
Background Hemostatic agents (HA), such as aluminium chloride (AlCl3) and ferric sulfate (FeSO4), can affect the dentin by obstructing adhesive penetration, and reducing the bond strength of self-adhesive resin cements (SARC) and glass ion…
View article: Structural and morphological characterization of silver nanoparticles intruded mineral trioxide aggregate admixture as a chair-side restorative medicament: an in vitro experimental study
Structural and morphological characterization of silver nanoparticles intruded mineral trioxide aggregate admixture as a chair-side restorative medicament: an in vitro experimental study Open
Objectives: The aim of this study was to create a rapid admixture of mineral trioxide aggregate (MTA) and silver nanoparticles (AgNPs) for chairside use in clinical settings to remediate the challenges associated with root canal treatment …
View article: நலடயர படலகளல தமழ மரததவம Tamil Medicine in Naladiyar
நலடயர படலகளல தமழ மரததவம Tamil Medicine in Naladiyar Open
In the changing human living environment, medicine has become an important aspect. Although human beings are progressing gradually, physical health continues to pose many challenges to human beings. In general, irregular eating habits and …
View article: In Vitro Evaluation of Flexural Strength, Impact Strength, and Surface Microhardness of <i>Vaccinium macrocarpon</i> Reinforced Polymethyl Methacrylate Denture Base Resin
In Vitro Evaluation of Flexural Strength, Impact Strength, and Surface Microhardness of <i>Vaccinium macrocarpon</i> Reinforced Polymethyl Methacrylate Denture Base Resin Open
Objective The antimicrobial efficacy of cranberry (CA) against oral infections was well evidenced. Influence of cranberry on the mechanical properties of heat‐activated polymethyl methacrylate (HA‐PMMA) denture base resin (DBR) is unexplor…
View article: Corrigendum to “Antibiofilm efficiency of silver and copper nanoparticle incorporated calcium hydroxide as an intracanal medicament: An in vitro study” [Journal of Oral Biology and Craniofacial Research 15 (2025) (2) 319–324]
Corrigendum to “Antibiofilm efficiency of silver and copper nanoparticle incorporated calcium hydroxide as an intracanal medicament: An in vitro study” [Journal of Oral Biology and Craniofacial Research 15 (2025) (2) 319–324] Open
[This corrects the article DOI: 10.1016/j.jobcr.2025.01.020.].
View article: Low-density neutrophils: A critical component in understanding the tumor microenvironment of oral squamous cell carcinoma
Low-density neutrophils: A critical component in understanding the tumor microenvironment of oral squamous cell carcinoma Open
Background: Tumour microenvironment is one of the evading research studies in the progression of cancers. Circulating neutrophil’s contribution to tumor growth and metastatic progression has been a matter of research interest. The phenotyp…
View article: Antibiofilm efficiency of silver and copper nanoparticle incorporated calcium hydroxide as an intracanal medicament: An in vitro study
Antibiofilm efficiency of silver and copper nanoparticle incorporated calcium hydroxide as an intracanal medicament: An in vitro study Open
Adding Cu and Ag NP to calcium hydroxide intracanal medication significantly increases its antibacterial activity against E. faecalis.
View article: Clinical and histopathological presentation of Histoplasmosis in the oral cavity - A Systematic review
Clinical and histopathological presentation of Histoplasmosis in the oral cavity - A Systematic review Open
Objective: Oral lesions can be an early indicator of systemic histoplasmosis, especially in immunocompromised patients. The main aim of this review was to summarise demographic and clinical findings and correlate them with histopathologica…
View article: Unveiling the Anticarcinogenic Efficacy of Nirgundi with Emphasis on Oral Cancer: A Comprehensive Review
Unveiling the Anticarcinogenic Efficacy of Nirgundi with Emphasis on Oral Cancer: A Comprehensive Review Open
India contributes one-third to the global cancer burden, which may be attributed to the fact that the diagnosis is usually made in the advanced stage. Oral cancer is the most common cancer, predominantly caused by the use of tobacco in mid…
View article: Antimicrobial role of Lavandula angustifolia towards Candida albicans, Streptococcus mutans, Staphylococcus aureus and anti-adherence effect on denture base resin
Antimicrobial role of Lavandula angustifolia towards Candida albicans, Streptococcus mutans, Staphylococcus aureus and anti-adherence effect on denture base resin Open
Incorporating lavender extract into denture base resin demonstrated promising antimicrobial properties. This investigation encourages further research to understand its effects on mechanical and physical properties of reinforced dental res…
View article: Immunomodulatory effects of Triphala and its constituents in oral squamous cell carcinoma and oral precancer
Immunomodulatory effects of Triphala and its constituents in oral squamous cell carcinoma and oral precancer Open
Oral squamous cell carcinoma shows increased occurrence in those who consume tobacco products, alcohol, betel quid, and areca nut, and is also considered to occur due to genetic alteration. Though there are numerous advancements in treatme…
View article: Evaluation of compressive and diametral tensile strength of novel bioactive material with conventional glass ionomer cement and silver amalgam: An in vitro study
Evaluation of compressive and diametral tensile strength of novel bioactive material with conventional glass ionomer cement and silver amalgam: An in vitro study Open
Aim: The aim of this study was to compare the compressive and tensile strength of two different brands of conventional glass ionomer cement (GIC), with new zirconia-reinforced GIC and silver amalgam. Materials and Methodology: Eighty speci…
View article: Analysis of single nucleotide polymorphism of p16 gene in cytological samples of patients with oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC)
Analysis of single nucleotide polymorphism of p16 gene in cytological samples of patients with oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) Open
Background: pl6 (CDKN2a) play a role in tumorigenesis in some head and neck squamous cell carcinomas. Frequent homozygous deletions of the pl6 gene have been reported in many tumor cell lines including the brain, breast, osteosarcomas, mel…
View article: Oral plasmablastic lymphoma in HIV‐infected individuals—A systematic review
Oral plasmablastic lymphoma in HIV‐infected individuals—A systematic review Open
Plasmablastic lymphoma (PBL) is an uncommon and aggressive large B‐cell lymphoma that affects immunocompromised individuals. The orofacial region is the most commonly affected site. The primary aim of the article was to review systematical…
View article: Prognostic significance of neutrophil to lymphocyte ratio (NLR) in oral squamous cell carcinoma
Prognostic significance of neutrophil to lymphocyte ratio (NLR) in oral squamous cell carcinoma Open
Background: Tumor microenvironment is one of the evading research in the progression of cancers. Circulating neutrophils reflect the system's inflammatory response and study the growth of tumor cells thereby inducing cancer progression. Ai…
View article: Evaluation of flexural strength and microhardness in Vaccinium macrocarpon (cranberry)-added self-cure polymethyl methacrylate dental resin: An in vitro study
Evaluation of flexural strength and microhardness in Vaccinium macrocarpon (cranberry)-added self-cure polymethyl methacrylate dental resin: An in vitro study Open
Aim: Occurrence of denture stomatitis and prosthesis breakage are common problems faced by elderly people wearing removable dentures. To overcome this, several attempts are made to improve the denture material by addition of antimicrobials…
View article: Salivary biomarkers in cancer - A narrative review
Salivary biomarkers in cancer - A narrative review Open
Cancer remains as the most persistent disease among human population and is one of the leading causes of morbidity and mortality worldwide. The effective treatment is related to not only the right selection of therapy but also dependent on…
View article: Comparative evaluation of salivary and serum CA 15-3 levels in tobacco users with and without potentially malignant oral disorders (PMOD) and oral squamous cell carcinoma (OSCC)
Comparative evaluation of salivary and serum CA 15-3 levels in tobacco users with and without potentially malignant oral disorders (PMOD) and oral squamous cell carcinoma (OSCC) Open
Background: The OSCC's prevalence has increased in recent years, which has made it ranked globally as the sixth malignancy and the third-ranked malignancy in Southeast Asia. The biomarker CA 15-3 have been studied in breast carcinoma and m…
View article: Differential expression of DNA fragmentation factor 45 in leukoplakia and oral squamous cell carcinoma and its correlation with TNF-α levels
Differential expression of DNA fragmentation factor 45 in leukoplakia and oral squamous cell carcinoma and its correlation with TNF-α levels Open
Background: DNA fragmentation factor (DFF) - 45, a heterodimeric protein, involved in apoptotic processes is found to play important role in various human cancers. Its role in the development and progression of oral cavity squamous cell ca…
View article: Understanding the properties and functional role of neutrophils in oral squamous cell carcinoma – A systematic review
Understanding the properties and functional role of neutrophils in oral squamous cell carcinoma – A systematic review Open
Background: OSCC, the most prevalent type of oral cancer, is thought to be caused by genetic alterations and is more common in people who use tobacco products, alcohol, betel quid, and areca nuts. Even with all of the breakthroughs in trea…
View article: Unicystic ameloblastoma with rare acanthomatous changes in mural Island
Unicystic ameloblastoma with rare acanthomatous changes in mural Island Open
Ameloblastomas are true benign odontogenic epithelial tumours, most frequently found in the jaw. It is the second most typical odontogenic neoplasm after odontoma. The most major odontogenic neoplasm, ameloblastomas come in a variety of cl…
View article: Oncostatin M [OSM] protein immuno-expression in oral squamous cell carcinoma – A prospective study
Oncostatin M [OSM] protein immuno-expression in oral squamous cell carcinoma – A prospective study Open
Background: An important factor in the progression of tumours is the formation of blood vessels in the tumour stroma. When there is an upregulation of angiogenesis stimulators or a downregulation of angiogenesis inhibitors, the tumour may …
View article: Endogenous nitroso compounds (NOC) from dietary source: Plausible promoters of oral carcinogenesis in non-smokers and non-alcoholics
Endogenous nitroso compounds (NOC) from dietary source: Plausible promoters of oral carcinogenesis in non-smokers and non-alcoholics Open
Goal of the perspective: Endogenous nitroso compounds (NOCs) from food sources contribute to oral carcinogenesis in non-smokers and non-alcoholics. Research in this field may lead to improved preventative and intervention methods for treat…
View article: Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective
Neurostimulation device for ameliorating salivary dysfunction: A novel neuromodulatory perspective Open
Xerostomia, or dry mouth, is a condition characterised by a decrease in salivary flow rate, affecting the quality of life of many individuals. Factors contributing to xerostomia include radiation therapy, pathologies, medications, and age-…
View article: Fractal dimensions in oral squamous cell carcinoma: A novel diagnostic paradigm
Fractal dimensions in oral squamous cell carcinoma: A novel diagnostic paradigm Open
Fractal dimension analysis is a novel computational method that quantifies the intricacy and irregularity of structures, and has demonstrated potential in numerous medical applications, such as the analysis of cancerous tissues. Our study …
View article: Biomaterials used in regeneration of salivary gland in three-dimensional culture system -a systematic review
Biomaterials used in regeneration of salivary gland in three-dimensional culture system -a systematic review Open
Background: Salivary gland dysfunction is caused by various pathological conditions including radiation therapy. Regeneration of the salivary gland components will pave a new path in restoring its function. Aim: This systematic review aims…
View article: Salivary 8-hydroxydeoxyguanosine (8-OHdG) – A potential DNA damage biomarker in tobacco chewers with and without periodontitis: A case control study
Salivary 8-hydroxydeoxyguanosine (8-OHdG) – A potential DNA damage biomarker in tobacco chewers with and without periodontitis: A case control study Open
• The present study revealed substantial differences in the concentration of salivary 8-OHdG between healthy controls, Tobacco chewers with periodontitis and tobacco chewers without periodontitis indicating that salivary 8-OHdG is a potent…
View article: Authors’ reply to Kumar
Authors’ reply to Kumar Open
We thank Kumar for her interest and critical comments in our article "Primary Ewing's sarcoma of the orofacial region: A narrative review."[1,2] We would like to address each of her valuable comments. In our narrative review, two authors p…
View article: Oral pemphigus vulgaris with one year follow-up and complete remission
Oral pemphigus vulgaris with one year follow-up and complete remission Open
Pemphigus vulgaris is a chronic autoimmune disorder that usually presents with blister formation which are mucocutaneous in nature that causes excruciating erosions. Although the cause of the illness is still unknown, Bulla development and…