Rajni Sharma
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View article: Enhancing the Socio-economic Empowerment of Jhumias in Mizoram through Livelihood Diversification Strategies
Enhancing the Socio-economic Empowerment of Jhumias in Mizoram through Livelihood Diversification Strategies Open
Mizoram, one of the eight sister states in India’s North Eastern region, has an agrarian economy that remains underdeveloped. The predominant agricultural practice, jhum (shifting cultivation), is characterized by low productivity and limi…
View article: Leading Hybrid and Remote Teams: Challenges, Strategies, and Performance Outcomes
Leading Hybrid and Remote Teams: Challenges, Strategies, and Performance Outcomes Open
Hybrid and remote work have reshaped how IT leaders communicate, build trust, and support their teams remotely. This paper explores the challenges of managing remote teams and lays out workable solutions for overcoming them. Based on exist…
View article: A pilot study of PSMA-targeted F-18-DCFPyL PET imaging of patients with adenoid cystic carcinoma
A pilot study of PSMA-targeted F-18-DCFPyL PET imaging of patients with adenoid cystic carcinoma Open
View article: Comparative GCMS-based profiling of phytochemical constituents from Azadirachta indica, Melia azedarach and Toona ciliata
Comparative GCMS-based profiling of phytochemical constituents from Azadirachta indica, Melia azedarach and Toona ciliata Open
For countless generations, Azadirachta indica, Melia azedarach and Toona ciliata have been widely recognised for their ethnobotanical properties, which have been utilised in the traditional medicinal purposes. The extracts derived from the…
View article: Effect of Nitrogen Scheduling on Growth and Yield of Wheat (Triticum aestivum L.)
Effect of Nitrogen Scheduling on Growth and Yield of Wheat (Triticum aestivum L.) Open
A field experiment was conducted at experimental farm, Department of Agronomy, Faculty of Agriculture and Veterinary Sciences, Mewar University Gangrar, Chittorgarh (Rajasthan) during Rabi season of 2023-24 to effect of nitrogen scheduling…
View article: A Study on the AI-Powered Social Media and Its Effects on Adolescent Mental Health
A Study on the AI-Powered Social Media and Its Effects on Adolescent Mental Health Open
The integration of artificial intelligence (AI) in social media platforms has transformed how adolescents interact, engage, and perceive the world around them. AI algorithms curate content, recommend connections, and create echo chambers t…
View article: Craft: Cross-modal Aligned Features Improve Robustness of Prompt Tuning
Craft: Cross-modal Aligned Features Improve Robustness of Prompt Tuning Open
Prompt Tuning has emerged as a prominent research paradigm for adapting vision-language models to various downstream tasks. However, recent research indicates that prompt tuning methods often lead to overfitting due to limited training sam…
View article: Associations Between Selected Micronutrient Deficiencies and Cognitive Function and Symptoms of Depression Among Non-pregnant Women of Reproductive Age in Punjab, India
Associations Between Selected Micronutrient Deficiencies and Cognitive Function and Symptoms of Depression Among Non-pregnant Women of Reproductive Age in Punjab, India Open
View article: Formulation and convergence analysis of an efficient higher order iterative scheme
Formulation and convergence analysis of an efficient higher order iterative scheme Open
This contribution presents a highly efficient three-step iterative scheme. The proposed scheme is different in itself by achieving seventh-order convergence. The scheme is very useful for equations of nonlinear nature having multiple roots…
View article: ASSESSMENT OF SHIFT IN THE ANTIBIOTIC SUSCEPTIBILITY PATTERN OF AEROBIC BACTERIAL ISOLATES FROM MICROBIAL BIOFILMS IN PATIENTS WITH ORAL SQUAMOUS CELL CARCINOMA AND PRECANCEROUS CONDITIONS
ASSESSMENT OF SHIFT IN THE ANTIBIOTIC SUSCEPTIBILITY PATTERN OF AEROBIC BACTERIAL ISOLATES FROM MICROBIAL BIOFILMS IN PATIENTS WITH ORAL SQUAMOUS CELL CARCINOMA AND PRECANCEROUS CONDITIONS Open
Background: Antimicrobial resistance is a concerning global health problem in reference to cancer patients as they are more susceptible to drug-resistant microorganisms because of their immunocompromised states. Aim: The aim of this study …
View article: Optimal eighth-order multiple root finding iterative methods using bivariate weight function
Optimal eighth-order multiple root finding iterative methods using bivariate weight function Open
In this contribution, a novel eighth-order scheme is presented for solving nonlinear equations with multiple roots. The proposed scheme comprises of three steps with the modified Newton method as its first step followed by two weighted New…
View article: Parents of Indian Children with Down Syndrome: Stigma and Health Related Quality of Life
Parents of Indian Children with Down Syndrome: Stigma and Health Related Quality of Life Open
View article: An Uncommon Presentation of Common Disease at Tertiary Care Centre of Northern India
An Uncommon Presentation of Common Disease at Tertiary Care Centre of Northern India Open
Snake bite is often met emergency in Indian subcontinent especially in rural settings. We sent a case of a 26-year-old male, residing in North India who sented with complaints of swelling over left leg along with breathlessness. His renal …
View article: Supplementary Figure 2 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 2 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Selection criteria used to narrow the proteins identified in the screen to those shown in this study.
View article: Data from Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation
Data from Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation Open
Pancreatic ductal adenocarcinoma (PDAC) is considered a “nonimmunogenic” neoplasm. Single-agent immunotherapies have failed to demonstrate significant clinical activity in PDAC and other “nonimmunogenic” tumors, in part due to a complex tu…
View article: Supplementary Figure 1 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 1 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Venn diagram showing overlap of proteins identified in 3 patients after the SASI screen.
View article: Supplementary Figures 1-4 and Supplementary Methods from Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment
Supplementary Figures 1-4 and Supplementary Methods from Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment Open
Supplementary Figure 1. The rate of proliferation is the same in the orthotopic and transgenic KPC mouse models Supplementary Figure 2. Single c-Met or Hh inhibitor treatment leads to the enhanced expression of the other target and the com…
View article: Data from Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features
Data from Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features Open
The Notch pathway is frequently altered in head and neck squamous cell carcinomas (HNSCC); however, the clinical significance of NOTCH1 dysregulation is poorly understood. This study was designed to characterize expression of the tr…
View article: Supplementary Figures 1 through 10 and Supplementary Tables 1 through 4 from Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation
Supplementary Figures 1 through 10 and Supplementary Tables 1 through 4 from Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation Open
Figure S1 Schema of the Neoadjuvant and Adjuvant Study of Panc GVAX. Figure S2 Pre- and post-vaccination mesothelin peptide-specific T cell levels in responders versus nonresponders. Figure S3 Intratumoral tertiary lymphoid aggregate in PD…
View article: Supplementary Table 1 from Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features
Supplementary Table 1 from Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features Open
Supplementary Table 1. Clinicopathological characteristics of tumors with NICD1 IHC available compared with unavailable.
View article: Supplementary Figure 5 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 5 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
MYPT1 and PSMC5 expression in 3 different subtypes (basal, HER-2 positive and ER positive) of breast cancer.
View article: Supplementary Table 2 from Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features
Supplementary Table 2 from Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features Open
Supplementary Table 2. Clinicopathological characteristics associated with NICD1 IHC staining pattern for NOTCH1-wild type only.
View article: Data from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Data from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Less than 6% of patients survive beyond the fifth year due to inadequate early diagnostics and ineffective treatment options. Our laboratory has d…
View article: Data from Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment
Data from Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment Open
Pancreatic ductal adenocarcinoma (PDAC) is one of the most chemotherapy- and radiotherapy-resistant tumors. The c-Met and Hedgehog (Hh) pathways have been shown previously by our group to be key regulatory pathways in the primary tumor gro…
View article: Data from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Data from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Less than 6% of patients survive beyond the fifth year due to inadequate early diagnostics and ineffective treatment options. Our laboratory has d…
View article: Supplementary Figure 5 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 5 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
MYPT1 and PSMC5 expression in 3 different subtypes (basal, HER-2 positive and ER positive) of breast cancer.
View article: Supplementary Figure 1 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 1 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Venn diagram showing overlap of proteins identified in 3 patients after the SASI screen.
View article: Supplementary Figure 4 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 4 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Additional immunohistochemical validation showing PSMC5, MYPT1 and TFRC expression in an independent set of pancreatic cancers.
View article: Supplementary Figures 1 through 10 and Supplementary Tables 1 through 4 from Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation
Supplementary Figures 1 through 10 and Supplementary Tables 1 through 4 from Immunotherapy Converts Nonimmunogenic Pancreatic Tumors into Immunogenic Foci of Immune Regulation Open
Figure S1 Schema of the Neoadjuvant and Adjuvant Study of Panc GVAX. Figure S2 Pre- and post-vaccination mesothelin peptide-specific T cell levels in responders versus nonresponders. Figure S3 Intratumoral tertiary lymphoid aggregate in PD…
View article: Supplementary Figure 3 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer
Supplementary Figure 3 from Using Quantitative Seroproteomics to Identify Antibody Biomarkers in Pancreatic Cancer Open
Western blots showing the antibody responses for PSMC5, MYPT1 and TFRC in patients with greater than and less than 3 years disease free survival