Rakesh C. Arora
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View article: The role of family caregivers in critical illness survivor recovery at home: A qualitative study
The role of family caregivers in critical illness survivor recovery at home: A qualitative study Open
Background When critical illness survivors are discharged home, they encounter a myriad of physical, emotional, cognitive, and socioeconomic challenges which can endure for an extended period of recovery. Given the extent of patient need, …
View article: EACTS Expert Consensus Document on protected cardiac surgery: pre-emptive use of temporary mechanical circulatory support in adult cardiac surgery patients at high risk for perioperative low cardiac output syndrome
EACTS Expert Consensus Document on protected cardiac surgery: pre-emptive use of temporary mechanical circulatory support in adult cardiac surgery patients at high risk for perioperative low cardiac output syndrome Open
Perioperative low cardiac output syndrome (LCOS) remains a significant complication in adult cardiac surgery, contributing to substantial morbidity, prolonged intensive care, and increased mortality. Its incidence is expected to rise furth…
View article: From hospital to home: A heightened window of vulnerability post-critical illness
From hospital to home: A heightened window of vulnerability post-critical illness Open
Background Healthcare innovations have not kept pace with the burden of critical illness survivorship. The majority of patients treated in an intensive care unit (ICU) will survive but suffer new or worsening physical, cognitive or mental …
View article: Scoping review of early mobility in the intensive care unit following cardiac surgery
Scoping review of early mobility in the intensive care unit following cardiac surgery Open
There is heterogeniety in the extant CS ICU early mobility literature, specifically in early mobility definitions and modes, outcome measures, quality of intervention reporting, and consideration of sex/gender. Improvements to research des…
View article: Clinical Course and Outcomes of Cardiogenic Shock in COVID-19 : Insights from COVID-19 Critical Care Consortium
Clinical Course and Outcomes of Cardiogenic Shock in COVID-19 : Insights from COVID-19 Critical Care Consortium Open
Aim: Cardiogenic shock (CS) is a life-threatening condition observed in patients with severe heart diseases. Although COVID-19 is known to cause cardiac complications, the epidemiology and outcomes of CS in COVID-19 patients have not been …
View article: Rosuvastatin-loaded injectable immunomodulatory hydrogel mitigates local immune response against transplanted stem cells and promotes heart repair in vivo
Rosuvastatin-loaded injectable immunomodulatory hydrogel mitigates local immune response against transplanted stem cells and promotes heart repair in vivo Open
In clinical trials allogeneic mesenchymal stem cells (MSCs) from young and healthy donors have shown promise to repair the heart following a heart attack. However, immune rejection of transplanted MSCs has prevented the clinical translatio…
View article: ECMO for the pregnant and peripartum patient: A practical review of indications, unique management considerations, and an approach framework
ECMO for the pregnant and peripartum patient: A practical review of indications, unique management considerations, and an approach framework Open
The use of extracorporeal membrane oxygenation (ECMO) to support the pregnant patient and fetus requires a complex decision-making process. Peripartum ECMO requires coordinated and informed decision-making between an interdisciplinary team…
View article: Mobility in a cardiac surgery intensive care unit: A behaviour mapping study
Mobility in a cardiac surgery intensive care unit: A behaviour mapping study Open
The existence of early mobility protocols does not mean that they are operational in the CS ICU. Integration of these protocols into CS ICU clinical care requires collaboration among researchers and clinicians.
View article: The role of Impella in the pre-procedural management of post-infarct ventricular septal defect: a systematic review
The role of Impella in the pre-procedural management of post-infarct ventricular septal defect: a systematic review Open
OBJECTIVES Post-infarct ventricular septal defect is a rare but devastating complication. Delayed treatment offers better outcomes than emergency surgery, but when acute cardiogenic shock or unstable haemodynamics occur, temporary mechanic…
View article: The Use of Arts‐Based Methods to Enhance Patient Engagement in Health Research
The Use of Arts‐Based Methods to Enhance Patient Engagement in Health Research Open
Introduction Patient and care partner engagement in research (PER) is important in generating knowledge to improve healthcare. Arts‐based methods (ABM) use art in the research process to share aesthetic knowledge, which is knowledge that m…
View article: Relationship between critical illness recovery and social determinants of health: a multiperspective qualitative study in British Columbia, Canada
Relationship between critical illness recovery and social determinants of health: a multiperspective qualitative study in British Columbia, Canada Open
Objectives There are health disparities and inequities in the outcomes of critical illness survivors related to the influence of social determinants of health on recovery. The purpose of this study was to describe the relationship between …
View article: Neurological Complications and Outcomes in Critically Ill Patients With COVID-19: Results From International Neurological Study Group From the COVID-19 Critical Care Consortium
Neurological Complications and Outcomes in Critically Ill Patients With COVID-19: Results From International Neurological Study Group From the COVID-19 Critical Care Consortium Open
Background In this COVID-19 Critical Care Consortium (CCCC) sub-study, we qualified neurological complications associated with SARS-CoV2 infection. Methods The CCCC is an international, multicenter study. Eligible patients were COVID-19 pa…
View article: Clinical Outcomes and Cost Analysis in Patients with Heart Failure Undergoing Transcatheter Edge-to-Edge Repair for Mitral Valve Regurgitation
Clinical Outcomes and Cost Analysis in Patients with Heart Failure Undergoing Transcatheter Edge-to-Edge Repair for Mitral Valve Regurgitation Open
Objective: To analyze the clinical and cost outcomes of transcatheter edge-to-edge repair (TEER) for mitral regurgitation (MR) in heart failure (HF) patients. Methods: All 162 HF patients undergoing TEER for MR between January 2019 and Mar…
View article: Enhanced Recovery After Surgery (ERAS) cardiac turnkey order set for perioperative pain management in cardiac surgery: Proceedings from the American Association for Thoracic Surgery (AATS) ERAS Conclave 2023
Enhanced Recovery After Surgery (ERAS) cardiac turnkey order set for perioperative pain management in cardiac surgery: Proceedings from the American Association for Thoracic Surgery (AATS) ERAS Conclave 2023 Open
There has been increased awareness regarding the potential short- and long-term adverse effects of both inadequate analgesia and excessive opioid administration after cardiac surgery. This turnkey order set aims to facilitate implementatio…
View article: Impact of Hemoglobin Levels on Composite Cardiac Arrest or Stroke Outcome in Patients With Respiratory Failure Due to COVID-19
Impact of Hemoglobin Levels on Composite Cardiac Arrest or Stroke Outcome in Patients With Respiratory Failure Due to COVID-19 Open
OBJECTIVES: Anemia has been associated with an increased risk of both cardiac arrest and stroke, frequent complications of COVID-19. The effect of hemoglobin level at ICU admission on a composite outcome of cardiac arrest or stroke in an i…
View article: The Role of the Cardiac Surgery Patient in Pain Management: The Patient Perspective
The Role of the Cardiac Surgery Patient in Pain Management: The Patient Perspective Open
One and a half million cardiac surgeries are completed worldwide each year where undertreated postoperative pain increases the risk of patient morbidity and mortality. Patient-centered pain management is recommended to improve patient outc…
View article: At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods Open
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples …
View article: Preoperative medication management turnkey order set for nonemergent adult cardiac surgery
Preoperative medication management turnkey order set for nonemergent adult cardiac surgery Open
Despite strong recommendations from major guidelines and consensus manuscripts, variation exists in preoperative medication orders, with limited availability of succinct implementation tools. This turnkey order set may facilitate standardi…
View article: The effect of a selenium-based anti-inflammatory strategy on postoperative functional recovery in high-risk cardiac surgery patients - A nested sub-study of the sustain CSX trial
The effect of a selenium-based anti-inflammatory strategy on postoperative functional recovery in high-risk cardiac surgery patients - A nested sub-study of the sustain CSX trial Open
A perioperative anti-inflammatory strategy with high-dose selenium supplementation did not improve functional recovery in high-risk cardiac surgery patients.