Rakesh Rana
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View article: Exploring the Homeopathic Therapeutic Potential of Acorus calamus: A Multi-center Open-Label Clinical Verification Study
Exploring the Homeopathic Therapeutic Potential of Acorus calamus: A Multi-center Open-Label Clinical Verification Study Open
Clinical verification in homeopathy is a systematic process that aims to validate the therapeutic efficacy of homeopathic medicines. The Central Council for Research in Homoeopathy (CCRH) has been conducting clinical verification studies i…
View article: Lumbar disc herniation with radiculopathy: Study protocol of a randomized controlled clinical trial evaluating the efficacy of Ayurveda treatment protocol. (Preprint)
Lumbar disc herniation with radiculopathy: Study protocol of a randomized controlled clinical trial evaluating the efficacy of Ayurveda treatment protocol. (Preprint) Open
BACKGROUND The single leading cause of disability worldwide is low back pain. The incidence of herniated disc is about 5-20 cases per 1000 adults per year and is prevalent in people in their third to fifth decade of life, with a male-to-f…
View article: Daily intranasal sesame oil instillation to improve nasal barrier function and mucosal immunity for respiratory health: A pilot randomized trial in healthy adults
Daily intranasal sesame oil instillation to improve nasal barrier function and mucosal immunity for respiratory health: A pilot randomized trial in healthy adults Open
Feasibility and preliminary efficacy of self-administered intranasal sesame oil instillation is demonstrated. A definitive RCT to evaluate it as a prophylaxis for respiratory health is needed.
View article: Clinical evaluation of Pushyanug Churna in the management of bacterial vaginosis: A prospective single-arm multicenter pilot study
Clinical evaluation of Pushyanug Churna in the management of bacterial vaginosis: A prospective single-arm multicenter pilot study Open
BACKGROUND: Bacterial vaginosis (BV) is among the most prevalent disorders of the female genital tract and is a common cause of leucorrhea. In Ayurvedic literature, the symptomatic presentation of BV can be correlated with Swetapradara . I…
View article: An Open-label Prospective Study to Assess the Effectiveness, Tolerability, and Safety of <i>Ayurvedic</i> Intervention (<i>Kutajarishta</i>) in the Treatment of Irritable Bowel Syndrome
An Open-label Prospective Study to Assess the Effectiveness, Tolerability, and Safety of <i>Ayurvedic</i> Intervention (<i>Kutajarishta</i>) in the Treatment of Irritable Bowel Syndrome Open
Background: Irritable Bowel Syndrome (IBS) is a major health problem that impacts around 15% of the world’s population. IBS has a detrimental impact on one’s quality of life and might lead to missed school or a job. Modern medicine for the…
View article: Efficacy and Safety of <i>Ayurveda</i> Compound Formulations in <i>Sthoulya</i> (Obesity) Management: A Multi-centric Clinical Trial
Efficacy and Safety of <i>Ayurveda</i> Compound Formulations in <i>Sthoulya</i> (Obesity) Management: A Multi-centric Clinical Trial Open
Background: Ayurveda offers a rich repository of medicinal formulations that have been traditionally used for various health conditions, including obesity. Scientific validation is essential to establish their efficacy and safety in contem…
View article: Clinical evaluation of Indukanta ghrita and Trayodashanga guggulu in the management of rheumatoid arthritis: A prospective open-label single-arm multicentric clinical trial
Clinical evaluation of Indukanta ghrita and Trayodashanga guggulu in the management of rheumatoid arthritis: A prospective open-label single-arm multicentric clinical trial Open
INTRODUCTION: Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily characterized by inflammatory arthritis and accompanied by extra-articular manifestations. Interaction of the genetic and environmental factors is a widely …
View article: Randomized double blind placebo controlled multicentric clinical trial of Ayush M-3 in the management of migraine- A study protocol
Randomized double blind placebo controlled multicentric clinical trial of Ayush M-3 in the management of migraine- A study protocol Open
The primary outcomes measures for the study will be changes in the character of disease in terms of frequency, intensity of headache as per VAS (0-10) and duration of episode of headache. Secondary outcome measure will be changes in MIDAS,…
View article: A community-based study for evaluation of Ayurvedic formulations in the management of Osteoarthritis Knee
A community-based study for evaluation of Ayurvedic formulations in the management of Osteoarthritis Knee Open
Background: Osteoarthritis (OA) of the knee is a major public health concern that leads to pain, disability and decreased quality of life. A similar condition has been described in Ayurveda under the name Sandhigata Vata which is caused by…
View article: Ayush-GMH as an add-on to vitamin E in Grade I and II non-alcoholic fatty liver disease: A study protocol for double-blind randomized placebo-controlled clinical trial
Ayush-GMH as an add-on to vitamin E in Grade I and II non-alcoholic fatty liver disease: A study protocol for double-blind randomized placebo-controlled clinical trial Open
BACKGROUND: Liver diseases account for 4% of global deaths, with cirrhosis and hepatocellular carcinoma being the leading causes. Non-alcoholic fatty liver disease (NAFLD), characterized by fat accumulation in the liver, is a significant c…
View article: Bayesian analysis in SPSS and STATA: A comparative scenario for researchers
Bayesian analysis in SPSS and STATA: A comparative scenario for researchers Open
Statistical software has a key role in data analysis in the current era of data-driven research. The various statistical methods that cannot be used due to mathematical complications can be performed through software such as Bayesian analy…
View article: Clinical evaluation of AYUSH-SL in patients receiving mass drug administration for treatment of chronic inflammatory lymphedema: A doubleblind placebo-controlled multicentric study
Clinical evaluation of AYUSH-SL in patients receiving mass drug administration for treatment of chronic inflammatory lymphedema: A doubleblind placebo-controlled multicentric study Open
Background & objectives: A 2.5-year placebo-controlled double-blind trial was conducted to investigate the safety and efficacy of AYUSH-SL, a poly-herbal ayurvedic formulation on filarial lymphedema in different endemic areas of India. Lym…
View article: Knowledge, attitude and practices of ayurvedic medicine practitioners in Kerala towards millets and millet-based diet: a prospective cross-sectional online survey study
Knowledge, attitude and practices of ayurvedic medicine practitioners in Kerala towards millets and millet-based diet: a prospective cross-sectional online survey study Open
Introduction Diet and lifestyle play pivotal roles in Ayurveda’s preventive and therapeutic principles. The rich culinary heritage of Kerala harmoniously aligns with Ayurvedic dietetic principles. With the recent designation of 2023 as the…
View article: Effectiveness of Composite Ayurveda Regimen in a Black Box Design for the Management of Rheumatoid Arthritis: Protocol of a Single Arm, Community-Based Study
Effectiveness of Composite Ayurveda Regimen in a Black Box Design for the Management of Rheumatoid Arthritis: Protocol of a Single Arm, Community-Based Study Open
Background Rheumatoid arthritis (RA) is an autoimmune disease that affects joints and can have extra-articular manifestations. RA usually tends to be progressive and leads to substantial health care burdens, both in terms of disability and…
View article: Effectiveness of Ayush Rasayana A and B on the Quality of Life of Older Adults: Protocol for a Cluster Randomized Controlled Trial
Effectiveness of Ayush Rasayana A and B on the Quality of Life of Older Adults: Protocol for a Cluster Randomized Controlled Trial Open
Background With advancing age among older adults, the associated debilities increase, indicating a deteriorating health status as there is a gradual loss of muscle mass, strength, and functionality. Ayush Rasayana A and B are coded Ayurved…
View article: Health and demographic indicators of selected districts of India: An impact of Swasthya Rakshan Programme (SRP)
Health and demographic indicators of selected districts of India: An impact of Swasthya Rakshan Programme (SRP) Open
Swasthya Rakshan Programme (SRP) provides health care services through Ayurveda, an initiative of the Government of India that aims to survey and create alertness of essential health appliances to ameliorate society from its grassroots lev…
View article: Effectiveness of Ayush Rasayana A and B on the Quality of Life of Older Adults: Protocol for a Cluster Randomized Controlled Trial (Preprint)
Effectiveness of Ayush Rasayana A and B on the Quality of Life of Older Adults: Protocol for a Cluster Randomized Controlled Trial (Preprint) Open
BACKGROUND With advancing age among older adults, the associated debilities increase, indicating a deteriorating health status as there is a gradual loss of muscle mass, strength, and functionality. Ayush Rasayana A and B are coded…
View article: Study protocol of a randomized, double-blind, placebo-controlled clinical trial on the efficacy and safety of an Ayurveda formulation (Ayush-SR) in the management of occupational stress among nurses
Study protocol of a randomized, double-blind, placebo-controlled clinical trial on the efficacy and safety of an Ayurveda formulation (Ayush-SR) in the management of occupational stress among nurses Open
BACKGROUND: Work-related stress has been found to have a detrimental effect on the individual’s productivity, quality of work, health, and personal life. Nursing has been identified as an occupation with high stress levels owing to complex…
View article: Safety and Prescription Trends of <i>Rasa Aushadhis</i> (<i>Ayurveda</i> Herbomineral Formulations): A Critical Appraisal of Reported Medical Practices from CCRAS Experience
Safety and Prescription Trends of <i>Rasa Aushadhis</i> (<i>Ayurveda</i> Herbomineral Formulations): A Critical Appraisal of Reported Medical Practices from CCRAS Experience Open
Background: In Ayurveda, metal and mineral-based formulations are popularly practised for their pleasant applicability and first-rate potency. There is no doubt about the safety and potency of Ayurveda Rasa Aushadhis if they are prepared a…
View article: Effectiveness of Composite Ayurveda Regimen in a Black Box Design for the Management of Rheumatoid Arthritis: Protocol of a Single Arm, Community-Based Study (Preprint)
Effectiveness of Composite Ayurveda Regimen in a Black Box Design for the Management of Rheumatoid Arthritis: Protocol of a Single Arm, Community-Based Study (Preprint) Open
BACKGROUND Rheumatoid arthritis (RA) is an autoimmune disease that affects joints and can have extra-articular manifestations. RA usually tends to be progressive and leads to substantial health care burdens, both in terms of disability an…
View article: Vatari Guggulu, Hingvashtaka Churna, and Brihat Saindhavadya Taila in the management of rheumatoid arthritis: An open-label, prospective, single-arm multi-center study
Vatari Guggulu, Hingvashtaka Churna, and Brihat Saindhavadya Taila in the management of rheumatoid arthritis: An open-label, prospective, single-arm multi-center study Open
Background: Despite significant advances in the diagnosis and treatment of rheumatoid arthritis (RA), the clinical outcomes remain unsatisfactory in a significant proportion of patients. Ayurveda management for RA ( Amavata ) has shown pro…
View article: The Role of Music in Mental Health Therapy During the COVID-19 Pandemic
The Role of Music in Mental Health Therapy During the COVID-19 Pandemic Open
The COVID-19 pandemic worsened the mental health situation globally, and the demand for effective intervention methods based on accessibility and innovation appears. Music therapy stands out as one of them as an important form of auxiliary…
View article: Clinical evaluation of Vyoshadi Guggulu and Panchasama Churna in the management of rheumatoid arthritis: An open-label, single-arm, prospective study
Clinical evaluation of Vyoshadi Guggulu and Panchasama Churna in the management of rheumatoid arthritis: An open-label, single-arm, prospective study Open
BACKGROUND: Rheumatoid arthritis (RA) is a chronic, degenerative disease of the connective tissue, mainly involving the synovial joints, characterized by swelling, pain, and tenderness in multiple joints, associated with morning stiffness,…
View article: Ashwagandha (Withania somnifera) and Shunthi (Zingiber officinale) in mild and moderate COVID-19: An open-label randomized controlled exploratory trial
Ashwagandha (Withania somnifera) and Shunthi (Zingiber officinale) in mild and moderate COVID-19: An open-label randomized controlled exploratory trial Open
Clinical Trial Registry of India - CTRI/2020/08/027224.
View article: Ayurveda compound formulations “Panchatikta ghrita” and “Gandhakadya malahara” in the management of Vicharchika (atopic eczema): A prospective open-label clinical trial
Ayurveda compound formulations “Panchatikta ghrita” and “Gandhakadya malahara” in the management of Vicharchika (atopic eczema): A prospective open-label clinical trial Open
Background: Eczema or atopic dermatitis is one of the significant public health concerns worldwide. Its prevalence is estimated to be 15–20% in children and 1–3% in adults. Moreover, the incidence of eczema has increased by 2–3-folds durin…
View article: Disease Characteristics, Care-Seeking Behavior, and Outcomes Associated With the Use of AYUSH-64 in COVID-19 Patients in Home Isolation in India: A Community-Based Cross-Sectional Analysis
Disease Characteristics, Care-Seeking Behavior, and Outcomes Associated With the Use of AYUSH-64 in COVID-19 Patients in Home Isolation in India: A Community-Based Cross-Sectional Analysis Open
Background During the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeutic care to patients with asymptomatic, mild, and moderate COVID-19 in home isolation based on the em…
View article: Safety and Efficacy of Ayurveda compound formulations (Kantakaryavaleha and Eladi Gutika) in the management of Mild Stable Bronchial Asthma (Tamaka Shwasa): Result from a prospective, open-label, multicenter, single-arm feasibility clinical trial.
Safety and Efficacy of Ayurveda compound formulations (Kantakaryavaleha and Eladi Gutika) in the management of Mild Stable Bronchial Asthma (Tamaka Shwasa): Result from a prospective, open-label, multicenter, single-arm feasibility clinical trial. Open
Background Bronchial asthma (BA) is a significant health problem and harms the quality of life, and better healthcare strategies are still needed for BA. Therefore, the scope of complementary and traditional medicine therapies on this conc…
View article: Effect of an Ayurvedic Intervention (Ayush-64) as a Stand-Alone Treatment in Mild to Moderate COVID-19: An Exploratory Prospective Single-Arm Clinical Trial
Effect of an Ayurvedic Intervention (Ayush-64) as a Stand-Alone Treatment in Mild to Moderate COVID-19: An Exploratory Prospective Single-Arm Clinical Trial Open
An Ayurvedic polyherbal formulation (Ayush-64) was repurposed for use in mild to moderate COVID-19 cases based on the supportive evidence obtained from a pilot study on its effect on Influenza like illness (ILI) and molecular docking study…
View article: CLINICAL EVALUATION OF AYUSH PE EYE DROPS IN THE MANAGEMENT OF ACUTE ALLERGIC CONJUNCTIVITIS: AN OPEN LABEL SINGLE ARM PROSPECTIVE MULTICENTER STUDY
CLINICAL EVALUATION OF AYUSH PE EYE DROPS IN THE MANAGEMENT OF ACUTE ALLERGIC CONJUNCTIVITIS: AN OPEN LABEL SINGLE ARM PROSPECTIVE MULTICENTER STUDY Open
IntroductionOcular allergy is one of the most common prevalent clinical conditions in the world with a rapid increase in the past few years. It has a multifactorial etiology and is a conjunctival inflammatory response due to IgE mediated m…
View article: AYUSH-64 as an adjunct to standard care in mild to moderate COVID-19: An open-label randomized controlled trial in Chandigarh, India
AYUSH-64 as an adjunct to standard care in mild to moderate COVID-19: An open-label randomized controlled trial in Chandigarh, India Open