Divya Patel
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View article: Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments
Real-world outcomes in patients with melanoma brain metastasis: a US multisite retrospective chart review study of systemic treatments Open
Objective This study examined real-world treatment patterns and outcomes in patients with melanoma brain metastasis (MBM) treated with first-line immunotherapy consisting of nivolumab plus ipilimumab or anti-programmed death-1 (PD-1) monot…
View article: Vulval tuberculosis - A masquerade reveler
Vulval tuberculosis - A masquerade reveler Open
Genital tuberculosis (TB) in females is a chronic disease with low-grade symptoms. It commonly occurs secondary to extragenital TB and rarely occurs primarily by inoculation from male partners. Owing to its rarity and variability of clinic…
View article: First-Line Nivolumab Plus Relatlimab Versus Nivolumab Plus Ipilimumab in Advanced Melanoma: An Indirect Treatment Comparison Using RELATIVITY-047 and CheckMate 067 Trial Data
First-Line Nivolumab Plus Relatlimab Versus Nivolumab Plus Ipilimumab in Advanced Melanoma: An Indirect Treatment Comparison Using RELATIVITY-047 and CheckMate 067 Trial Data Open
PURPOSE Nivolumab plus relatlimab and nivolumab plus ipilimumab have been approved for advanced melanoma on the basis of the phase II/III RELATIVITY-047 and phase III CheckMate 067 trials, respectively. As no head-to-head trial comparing t…
View article: Effectiveness of provider communication training for increasing human papillomavirus vaccine initiation at a safety-net health system
Effectiveness of provider communication training for increasing human papillomavirus vaccine initiation at a safety-net health system Open
Our provider feedback intervention had minimal effect on increasing prevalence of HPV vaccination in seven family medicine and pediatric clinics. Novel strategies are needed to address provider barriers related to HPV vaccination.
View article: Assessing the Performance of Video Classification Models in Identifying Violent Actions
Assessing the Performance of Video Classification Models in Identifying Violent Actions Open
Manual video surveillance takes time and is prone to human error. Thanks to machine learning and deep learning, video analytics automates these processes. Video classification is an important aspect of video analytics. It is critical to de…
View article: Association between plasma adiponectin levels and severity of acute ischemic stroke
Association between plasma adiponectin levels and severity of acute ischemic stroke Open
There is little documentation describing the correlation between plasma adiponectin and the severity of ischemic stroke in the Indian population. The present study was aimed to find the correlation between plasma adiponectin levels and sev…
View article: Correlation of Suppression of Tumourigenicity 2 with hsCRP, NT-proBNP and Left Ventricular Ejection Fraction in Patients with Myocardial Infarction
Correlation of Suppression of Tumourigenicity 2 with hsCRP, NT-proBNP and Left Ventricular Ejection Fraction in Patients with Myocardial Infarction Open
Introduction: Soluble Suppression of Tumourigenicity 2 (sST2) represents a clinically relevant biomarker and has predictive evidence in acute Myocardial Infarction (MI) and predicts cardiovascular death and risk of heart failure developmen…
View article: Simultaneous quantification of teneligliptin hydrobromide and metformin hydrochloride: An improved HPTLC method with implementation of Plackett-Burman design
Simultaneous quantification of teneligliptin hydrobromide and metformin hydrochloride: An improved HPTLC method with implementation of Plackett-Burman design Open
Simple, rapid, sensitive, robust, and validated high-performance thin-layer chromatography was developed for the simultaneous estimation of anti-diabetic drugs Teneligliptin hydrobromide (TH) and Metformin hydrochloride (MH) in bulk and ph…
View article: Eastern Equine Encephalitis
Eastern Equine Encephalitis Open
A 68-year-old woman presented to the emergency department with chills, fatigue, and a sore throat of 1 week duration. Three days prior to presentation, her symptoms had progressed to generalized weakness and altered mental status.
View article: Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome
Strongyloidosis Hyperinfection Syndrome in an HIV-Infected Patient: A Rare Manifestation of Immune Reconstitution Inflammatory Syndrome Open
Parasitic infections such as Strongyloides stercoralis and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, S. stercoralis can progress to strongyloidiasis hyperinfec…
View article: AIDS Cholangiopathy Secondary to Cytomegalovirus as Possible Unmasking Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Individual: Case Report and Review of the Literature
AIDS Cholangiopathy Secondary to Cytomegalovirus as Possible Unmasking Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Individual: Case Report and Review of the Literature Open
We present the first case report of cytomegalovirus (CMV) cholangiopathy as possible immune reconstitution inflammatory syndrome (IRIS) in a human immunodeficiency virus (HIV)-infected individual, within two months of starting effective HA…
View article: Spatial-Temporal Variability and Characterisation of Aerosols in Urban Air Quality of Ahmedabad, India, based on Field and Satellite Data
Spatial-Temporal Variability and Characterisation of Aerosols in Urban Air Quality of Ahmedabad, India, based on Field and Satellite Data Open
Particulate matter (PM), or aerosol play an important role in Air Quality.Ahmedabad is an urban, industrialized and one of the fastest growing city in Western India.This study presents spatio-temporal variability in mass concentrations of …
View article: Inactivation of <scp>ID</scp>4 promotes a <scp>CRPC</scp> phenotype with constitutive <scp>AR</scp> activation through <scp>FKBP</scp>52
Inactivation of <span>ID</span>4 promotes a <span>CRPC</span> phenotype with constitutive <span>AR</span> activation through <span>FKBP</span>52 Open
Castration‐resistant prostate cancer ( CRPC ) is the emergence of prostate cancer cells that have adapted to the androgen‐depleted environment of the prostate. In recent years, targeting multiple chaperones and co‐chaperones (e.g., Hsp27, …
View article: Adapting Pre-trained Word Embeddings For Use In Medical Coding
Adapting Pre-trained Word Embeddings For Use In Medical Coding Open
Word embeddings are a crucial component in modern NLP. Pre-trained embeddings released by different groups have been a major reason for their popularity. However, they are trained on generic corpora, which limits their direct use for domai…
View article: ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation
ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation Open
Given that mutated p53 (50% of all human cancers) is over-expressed in many cancers, restoration of mutant p53 to its wild type biological function has been sought after as cancer therapy. The conformational flexibility has allowed to rest…