Ralf Rabus
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View article: Structural and regulatory determinants of flagellar motility in <i>Rhodobacterales</i> —the archetypal flagellum of <i>Phaeobacter inhibens</i> DSM 17395
Structural and regulatory determinants of flagellar motility in <i>Rhodobacterales</i> —the archetypal flagellum of <i>Phaeobacter inhibens</i> DSM 17395 Open
Flagellar motility is crucial for the swim-and-stick lifestyle and plays an important role in bacterial-algal interactions of Rhodobacterales . This alphaproteobacterial order contains three distinct types of flagellar gene clusters (FGCs)…
View article: Zellbiologie-Physiologie-Interaktion in der marinen Mikroalge P. cordatum
Zellbiologie-Physiologie-Interaktion in der marinen Mikroalge P. cordatum Open
Dinoflagellates are unicellular eukaryotes with striking cell-biology and genomes and are major drivers of global primary production. Marine Prorocentrum cordatum has a barrel-like chloroplast, reticular mitochondrion, and unique nucleus. …
View article: 7β-Hydroxysteroid dehydratase Hsh3 eliminates the 7-hydroxy group of the bile salt ursodeoxycholate during degradation by <i>Sphingobium</i> sp. strain Chol11 and other <i>Sphingomonadaceae</i>
7β-Hydroxysteroid dehydratase Hsh3 eliminates the 7-hydroxy group of the bile salt ursodeoxycholate during degradation by <i>Sphingobium</i> sp. strain Chol11 and other <i>Sphingomonadaceae</i> Open
Bile salts are steroids with distinctive hydroxylation patterns that are produced and excreted by vertebrates. In contrast to common human bile salts, ursodeoxycholate (UDCA) has a 7-hydroxy group in β-configuration and is used in large am…
View article: Genetic Blueprint for Stringent Response in Betaproteobacterial Aromatoleum/Azoarcus/Thauera Cluster
Genetic Blueprint for Stringent Response in Betaproteobacterial Aromatoleum/Azoarcus/Thauera Cluster Open
Background: The Aromatoleum/Azoarcus/Thauera (AAT) cluster comprises anaerobic degradation specialists (Aromatoleum, Thauera) and N2-fixing endophytes (Azoarcus). Omics-based and genetic studies with associated model strains implicate stri…
View article: Structural and regulatory determinants of flagellar motility in<i>Rhodobacterales</i>– The archetypal flagellum of<i>Phaeobacter inhibens</i>DSM 17395
Structural and regulatory determinants of flagellar motility in<i>Rhodobacterales</i>– The archetypal flagellum of<i>Phaeobacter inhibens</i>DSM 17395 Open
Flagellar motility is crucial for the swim-and-stick lifestyle of Rhodobacterales and plays an important role for bacterial-algal interactions. This alphaproteobacterial order contains three distinct types of flagellar gene clusters (FGCs)…
View article: Key role of <i>Desulfobacteraceae</i> in C/S cycles of marine sediments is based on congeneric catabolic-regulatory networks
Key role of <i>Desulfobacteraceae</i> in C/S cycles of marine sediments is based on congeneric catabolic-regulatory networks Open
Marine sediments are highly bioactive habitats, where sulfate-reducing bacteria contribute substantially to seabed carbon cycling by oxidizing ~77 Tmol C org year −1 . This remarkable activity is largely attributable to the deltaproteobact…
View article: 7β-hydroxysteroid dehydratase Hsh3 eliminates the 7-hydroxy group of the bile salt ursodeoxycholate during degradation by<i>Sphingobium</i>sp. strain Chol11 and other<i>Sphingomonadaceae</i>
7β-hydroxysteroid dehydratase Hsh3 eliminates the 7-hydroxy group of the bile salt ursodeoxycholate during degradation by<i>Sphingobium</i>sp. strain Chol11 and other<i>Sphingomonadaceae</i> Open
Bile salts are steroids with distinctive hydroxylation patterns that are produced and excreted by vertebrates. In contrast to common human bile salts, ursodeoxycholate (UDCA) has a 7-hydroxy group in β-configuration and is used in large am…
View article: Multifaceted Dinoflagellates and the Marine Model Prorocentrum cordatum
Multifaceted Dinoflagellates and the Marine Model Prorocentrum cordatum Open
Background: Dinoflagellates are a monophyletic group within the taxon Alveolata, which comprises unicellular eukaryotes. Dinoflagellates have long been studied for their organismic and morphologic diversity as well as striking cellular fea…
View article: Global growth phase response of the gut bacterium Phocaeicola vulgatus (phylum Bacteroidota)
Global growth phase response of the gut bacterium Phocaeicola vulgatus (phylum Bacteroidota) Open
Phocaeicola vulgatus belongs to the intestinal microbiome, where it fermentatively breaks down of food-derived biopolymers , thereby, contributing to the gut metabolome. Moreover, due to its product range, P. vulgatus is a potential nonsta…
View article: Rich microbial and depolymerising diversity in Antarctic krill gut
Rich microbial and depolymerising diversity in Antarctic krill gut Open
With almost a quadrillion individuals, the Antarctic krill processes five million tons of organic carbon every day during austral summer. This high carbon flux requires a broad range of hydrolytic enzymes to decompose the diverse food-deri…
View article: Conspicuous chloroplast with light harvesting-photosystem I/II megacomplex in marine <i>Prorocentrum cordatum</i>
Conspicuous chloroplast with light harvesting-photosystem I/II megacomplex in marine <i>Prorocentrum cordatum</i> Open
Marine photosynthetic (micro)organisms drive multiple biogeochemical cycles and display a large diversity. Among them, the bloom-forming, free-living dinoflagellate Prorocentrum cordatum CCMP 1329 (formerly P. minimum) stands out with its …
View article: The blue light-dependent LOV-protein LdaP of Dinoroseobacter shibae acts as antirepressor of the PpsR repressor, regulating photosynthetic gene cluster expression
The blue light-dependent LOV-protein LdaP of Dinoroseobacter shibae acts as antirepressor of the PpsR repressor, regulating photosynthetic gene cluster expression Open
In the marine α-proteobacterium Dinoroseobacter shibae more than 40 genes of the aerobic anoxygenic photosynthesis are regulated in a light-dependent manner. A genome-wide screen of 5,605 clones from a D. shibae transposon library for loss…
View article: Catabolic Network of the Fermentative Gut Bacterium <i>Phocaeicola vulgatus</i> (Phylum Bacteroidota) from a Physiologic-Proteomic Perspective
Catabolic Network of the Fermentative Gut Bacterium <i>Phocaeicola vulgatus</i> (Phylum Bacteroidota) from a Physiologic-Proteomic Perspective Open
Introduction: Phocaeicola vulgatus (formerly Bacteroides vulgatus) is a prevalent member of human and animal guts, where it influences by its dietary-fiber-fueled, fermentative metabolism the microbial community as well as the host health.…
View article: Supplementary Material for: Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidetes) from a physiologic-proteomic perspective
Supplementary Material for: Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidetes) from a physiologic-proteomic perspective Open
Phocaeicola vulgatus (formerly Bacteroides vulgatus) is a prevalent member of human and animal guts, where it influences by its dietary fiber-fueled, fermentative metabolism the microbial community as well as the host health. To refine the…
View article: Supplementary Material for: Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidetes) from a physiologic-proteomic perspective
Supplementary Material for: Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidetes) from a physiologic-proteomic perspective Open
Phocaeicola vulgatus (formerly Bacteroides vulgatus) is a prevalent member of human and animal guts, where it influences by its dietary fiber-fueled, fermentative metabolism the microbial community as well as the host health. To refine the…
View article: Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate
Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate Open
Background “Red tides” are harmful algal blooms caused by dinoflagellate microalgae that accumulate toxins lethal to other organisms, including humans via consumption of contaminated seafood. These algal blooms are driven by a combination …
View article: Sensitive and selective phenol sensing in denitrifying <i>Aromatoleum aromaticum</i> EbN1 <sup>T</sup>
Sensitive and selective phenol sensing in denitrifying <i>Aromatoleum aromaticum</i> EbN1 <sup>T</sup> Open
Aromatoleum aromaticum EbN1 T anaerobically degrades phenol, p -cresol, and p -ethylphenol, each via a distinct peripheral pathway. The compound-specific regulation of each pathway is proposed to occur on the transcriptional level in the c…
View article: The Catabolic Network of <b><i>Aromatoleum aromaticum</i></b> EbN1<sup>T</sup>
The Catabolic Network of <b><i>Aromatoleum aromaticum</i></b> EbN1<sup>T</sup> Open
The denitrifying betaproteobacterium Aromatoleum aromaticum EbN1T is a facultative anaerobic degradation specialist and belongs to the environmental bacteria studied best on the proteogenomic level. This review summarizes the current state…
View article: The enigmatic nucleus of the marine dinoflagellate <i>Prorocentrum cordatum</i>
The enigmatic nucleus of the marine dinoflagellate <i>Prorocentrum cordatum</i> Open
The marine, bloom-forming dinoflagellate Prorocentrum cordatum CCMP 1329 (formerly P. minimum ) has a genome atypical of eukaryotes, with a large size of ~4.15 Gbp, organized in plentiful, highly condensed chromosomes and packed in a dinof…
View article: Systems Biology of Aromatic Compound Catabolism in Facultative Anaerobic <i>Aromatoleum aromaticum</i> EbN1 <sup>T</sup>
Systems Biology of Aromatic Compound Catabolism in Facultative Anaerobic <i>Aromatoleum aromaticum</i> EbN1 <sup>T</sup> Open
Aromatic compounds are abundant constituents not only of natural organic matter but also of bulk industrial chemicals and fuel components of environmental concern. Considering the widespread occurrence of redox gradients in the biosphere, …
View article: A Novel Coenzyme A Analogue in the Anaerobic, Sulfate‐Reducing, Marine Bacterium <i>Desulfobacula toluolica</i> Tol2<sup>T</sup>
A Novel Coenzyme A Analogue in the Anaerobic, Sulfate‐Reducing, Marine Bacterium <i>Desulfobacula toluolica</i> Tol2<sup>T</sup> Open
Coenzyme A (CoA) thioesters are formed during anabolic and catabolic reactions in every organism. Degradation pathways of growth‐supporting substrates in bacteria can be predicted by differential proteogenomic studies. Direct detection of …
View article: Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate
Multi-omics analysis reveals the molecular response to heat stress in a “red tide” dinoflagellate Open
“Red tides” are harmful algal blooms (HABs) caused by dinoflagellate microalgae that accumulate toxins lethal to other organisms, including humans via consumption of contaminated seafood. Increasingly frequent, HABs are driven by a combina…
View article: Transcriptome–proteome compendium of the Antarctic krill (<i>Euphausia superba</i>): Metabolic potential and repertoire of hydrolytic enzymes
Transcriptome–proteome compendium of the Antarctic krill (<i>Euphausia superba</i>): Metabolic potential and repertoire of hydrolytic enzymes Open
The Antarctic krill ( Euphausia superba Dana) is a keystone species in the Southern Ocean that uses an arsenal of hydrolases for biomacromolecule decomposition to effectively digest its omnivorous diet. The present study builds on a hybrid…
View article: Complex and flexible catabolism in <i>Aromatoleum aromaticum</i> <scp>pCyN1</scp>
Complex and flexible catabolism in <i>Aromatoleum aromaticum</i> <span>pCyN1</span> Open
Summary Large quantities of organic matter are continuously deposited, and (a)biotic gradients intersect in the soil–rhizosphere, where biodegradation contributes to the global cycles of elements. The betaproteobacterial genus Aromatoleum …
View article: Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination
Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination Open
During adult neurogenesis, neuronal stem cells differentiate into mature neurons that are functionally integrated into the existing network. One hallmark during the late phase of this neurodifferentiation process is the formation of dendri…
View article: Nanomolar Responsiveness of Marine <b><i>Phaeobacter inhibens</i></b> DSM 17395 toward Carbohydrates and Amino Acids
Nanomolar Responsiveness of Marine <b><i>Phaeobacter inhibens</i></b> DSM 17395 toward Carbohydrates and Amino Acids Open
Phaeobacter inhibens DSM 17395 is a heterotrophic member of the ubiquitous, marine Roseobacter group and specializes in the aerobic utilization of carbohydrates and amino acids via pathways widespread among roseobacters. The in vivo respon…
View article: Luciferase-Based Determination of ATP/NAD(H) Pools in a Marine (Environmental) Bacterium
Luciferase-Based Determination of ATP/NAD(H) Pools in a Marine (Environmental) Bacterium Open
In all living organisms, adenosine triphosphate (ATP) and NAD(H) represent universal molecular currencies for energy and redox state, respectively, and are thus widely applicable molecular proxies for an organism’s viability and activity. …
View article: Supplementary Material for: Luciferase-Based Determination of ATP/NAD(H) Pools in a Marine (Environmental) Bacterium
Supplementary Material for: Luciferase-Based Determination of ATP/NAD(H) Pools in a Marine (Environmental) Bacterium Open
In all living organisms, adenosine triphosphate (ATP) and NAD(H) represent universal molecular currencies for energy and redox state, respectively, and are thus widely applicable molecular proxies for an organism’s viability and activity. …
View article: Supplementary Material for: Nanomolar responsiveness of marine Phaeobacter inhibens DSM 17395 toward carbohydrates and amino acids
Supplementary Material for: Nanomolar responsiveness of marine Phaeobacter inhibens DSM 17395 toward carbohydrates and amino acids Open
Phaeobacter inhibens DSM 17395 is a heterotrophic member of the ubiquitous, marine Roseobacter group and specialized in the aerobic utilization of carbohydrates and amino acids via pathways widespread among roseobacters. The in vivo respon…