Ramanathan Sathianathan
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View article: Efficacy, Safety and Tolerability of Clonazepam 0.25 mg and Propranolol 10/20 mg Fixed-dose Combination among Anxiety Disorder Patients: A Randomized, Double-blind, Multicentric, Active-controlled, Phase IV Study
Efficacy, Safety and Tolerability of Clonazepam 0.25 mg and Propranolol 10/20 mg Fixed-dose Combination among Anxiety Disorder Patients: A Randomized, Double-blind, Multicentric, Active-controlled, Phase IV Study Open
Background and aim: Although monotherapy of anti-anxiety drugs is effective in controlling anxiety, due to the progressive nature of the disease, it is often associated with a lack of effectiveness over time. So, this study was carried out…
View article: Caregiver Strain in Children with Attention Deficit Hyperactivity Disorder: A Cross-Sectional Study
Caregiver Strain in Children with Attention Deficit Hyperactivity Disorder: A Cross-Sectional Study Open
Background: Attention Deficit Hyperactivity Disorder (ADHD) is among the most prevalent psychiatric disorders observed in children, which causes significant caregiver burden in terms of psychological, emotional, physical, and financial sta…
View article: Clinician’s Opinion on Depression and Role of Escitalopram in the Management of Depression
Clinician’s Opinion on Depression and Role of Escitalopram in the Management of Depression Open
Background: Depression is an emerging severe disorder and a serious public health problem, which can often go undetected. It is associated with many disease conditions. Increase in non-communicable diseases, suicide rate, has made its inci…
View article: Metabolic Syndrome and Lifestyle Factors in Patients with Schizophrenia: A Cross-Sectional Hospital-Based Study
Metabolic Syndrome and Lifestyle Factors in Patients with Schizophrenia: A Cross-Sectional Hospital-Based Study Open
Background: Patients with schizophrenia are more likely to develop cardiovascular diseases such as myocardial infarction and stroke which result in premature deaths. The increased prevalence of these risk factors can be attributed to sever…
View article: Personalized Approach in the Management of Difficult-to-Treat and Treatment-Resistant Depression With Second-Generation Antipsychotics: A Delphi Statement
Personalized Approach in the Management of Difficult-to-Treat and Treatment-Resistant Depression With Second-Generation Antipsychotics: A Delphi Statement Open
Background Major depressive disorder (MDD) has many facets including mixed or atypical depression that requires personalized care to improve treatment-related outcomes. Second-generation antipsychotics (SGAs) offer complementary mechanisms…
View article: Impact of Serotonin Pathway Gene Polymorphisms and Serotonin Levels in Suicidal Behaviour
Impact of Serotonin Pathway Gene Polymorphisms and Serotonin Levels in Suicidal Behaviour Open
Objective: Suicide is a significant public health issue and a major cause of death in all ages worldwide. Previous studies have shown the involvement of genetics in suicidal behaviour. This study aimed to assess the role of the genetic var…
View article: Development and Validation of Yoga Protocol for Patients with Depression
Development and Validation of Yoga Protocol for Patients with Depression Open
Background: Scientific evidence suggests that yoga is beneficial for treating mental health disorders. To the best of our knowledge, minimal studies have been done on the development of a yoga module for the specific clinical aspects of de…
View article: Knowledge and Attitude toward Electroconvulsive Therapy among MBBS Interns
Knowledge and Attitude toward Electroconvulsive Therapy among MBBS Interns Open
Background: Electroconvulsive therapy (ECT) remains the most effective modality of treatment in many major mental health disorders, which calls for a rapid response. However, the media's portrayal of ECT as inhumane has resulted in a flawe…
View article: MU-Opioid Receptor (OPRM1) Gene Polymorphism and its Association with Alcohol Dependence: A Single Centre Study from Southern India
MU-Opioid Receptor (OPRM1) Gene Polymorphism and its Association with Alcohol Dependence: A Single Centre Study from Southern India Open
Introduction: Asn40Asp Opioid Receptor (OPRM1) polymorphism of the MU-OPRM1 gene has been widely studied with regard to its association with alcohol dependence however results have been conflicting with evidence of ethnicity mediated effec…
View article: A cross-sectional study of prevalence and predictors of psychological distress during COVID-19 pandemic among the Indian population
A cross-sectional study of prevalence and predictors of psychological distress during COVID-19 pandemic among the Indian population Open
Objectives: To assess the prevalence of psychological distress and identify the predictors and factors associated with the distress during the onset of COVID-19 pandemic among Indian population. Methods: An online cross-sectional study wit…
View article: Antenatal Depression and Generalized Anxiety Disorder in a Tertiary Hospital in South India
Antenatal Depression and Generalized Anxiety Disorder in a Tertiary Hospital in South India Open
Background: Antenatal depression is associated with several adverse maternal outcomes, perinatal outcomes, lower academic achievements in adolescence, and future mental health problems for the mothers. Early identification and effective tr…
View article: Socio-Demographic, Clinical Profile, Life Stress Events and Psychiatric Comorbidities in Patients with First Attempt Suicide
Socio-Demographic, Clinical Profile, Life Stress Events and Psychiatric Comorbidities in Patients with First Attempt Suicide Open
Background: Contemporary literature focuses on various socio-demographic, clinical profile and psychiatric comorbitidies in patients with first attempt suicide. Aim: 1. To study the socio-demographic factors and the clinical profile of sub…
View article: Sexual Dysfunction and Marital Relationship in Women With Schizophrenia in Comparison with Caregivers: A Hospital-based Study
Sexual Dysfunction and Marital Relationship in Women With Schizophrenia in Comparison with Caregivers: A Hospital-based Study Open
Background: Sexual dysfunction is common in females with schizophrenia and is attributed to multiple causes, including individual psychopathology and antipsychotics. Understanding the impact of relationship satisfaction on sexual functioni…
View article: Occurrence and Motives Associated with Relapse after a De-addiction Treatment in Men with Alcohol Dependence Syndrome in a Tertiary Care HospitalA Cross-sectional Study
Occurrence and Motives Associated with Relapse after a De-addiction Treatment in Men with Alcohol Dependence Syndrome in a Tertiary Care HospitalA Cross-sectional Study Open
Introduction: Alcohol dependence is a chronic relapsing brain disorder. A combination of biological, psychological and social factors influences the outcome of de-addiction treatment. Understanding these factors help in formulation of effe…
View article: Risperidone-induced retrograde ejaculation and lurasidone may be the alternative
Risperidone-induced retrograde ejaculation and lurasidone may be the alternative Open
Medication adherence with antipsychotics is adversely impacted by the burden of untoward adverse effects. In particular, sexual side effects are often underreported by patients, which may interfere with drug compliance. Presented here is t…
View article: Behavioral problems and temperamental characteristics among children in alcoholic families
Behavioral problems and temperamental characteristics among children in alcoholic families Open
Background: Children of alcoholics (COAs) are at high risk for behavioral problems and temperamental difficulties. Aim: The aim of this study was to compare the behavioral problems and temperamental characteristics in children of persons w…
View article: A rare case report of alektorophobia in an adult male
A rare case report of alektorophobia in an adult male Open
Alektorophobia is a term specific to fear of chickens/hens. It is a type of ornithophobia (fear of birds) which comes under specific phobia, animal type. Alektorophobia is derived from the Greek word ”Alektor” which means ”rooster” and ”ph…
View article: The dementia epidemic: Impact, prevention, and challenges for India
The dementia epidemic: Impact, prevention, and challenges for India Open
In 1947, when India achieved independence, the average life expectancy of an Indian was 32 years, with birth rate being high and few people surviving to old age. With the advancement of medical sciences and implementation of family plannin…
View article: Caregiver Burden in Alcohol Dependence Syndrome
Caregiver Burden in Alcohol Dependence Syndrome Open
Background . Alcoholism is a major threat to the individual as well as the society and the maximum burden of the illness is borne by the family. Aim . The study is aimed at assessing the pattern of burden on the caregivers of alcohol depen…
View article: COMPARATIVE STUDY ON EARLY ONSET AND LATE ONSET ALCOHOL DEPENDENCE PATIENTS
COMPARATIVE STUDY ON EARLY ONSET AND LATE ONSET ALCOHOL DEPENDENCE PATIENTS Open
CONTEXTEarly onset of alcohol use is a major public health concern in terms of its impact on adolescent morbidity and mortality. AIMComparative study of early and late onset alcohol dependent patients with their correlates such as demograp…