Rami Doukky
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View article: American Society of Nuclear Cardiology quality metrics for cardiac amyloid radionuclide imaging
American Society of Nuclear Cardiology quality metrics for cardiac amyloid radionuclide imaging Open
This document from the American Society of Nuclear Cardiology develops metrics for the assessment of quality for laboratories that perform cardiac amyloid radionuclide imaging. These metrics are based on clinical guidelines, appropriate us…
View article: Cardiovascular Testing in the United States during the COVID-19 Pandemic: Volume Recovery and Worldwide Comparison
Cardiovascular Testing in the United States during the COVID-19 Pandemic: Volume Recovery and Worldwide Comparison Open
The reductions in cardiac testing during the early pandemic have recovered within a year to prepandemic baselines in the United States and NUHICs, while procedure volumes remain depressed in lower-income countries.Keywords: SPECT, Cardiac,…
View article: Chronological comparison of TAVI and SAVR stratified to surgical risk: a systematic review, meta-analysis, and meta-regression
Chronological comparison of TAVI and SAVR stratified to surgical risk: a systematic review, meta-analysis, and meta-regression Open
Transcatheter aortic valve implantation (TAVI) has been established as a reasonable alternative to surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis. However, long-term outcomes including valve durability and…
View article: Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding
Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding Open
Introduction We sought to investigate the association between left-sided prosthetic valve dysfunction and gastrointestinal (GI) bleeding. Methods In a retrospective cohort of patients with left-sided prostheses, we identified those who exp…
View article: Prevalence and predictors of Twiddler's syndrome
Prevalence and predictors of Twiddler's syndrome Open
Background Twiddler's syndrome is a poorly understood clinical phenomenon when patients either consciously or subconsciously rotate their cardiac device resulting in lead dislodgement. We aimed to determine the true prevalence and risk fac…
View article: Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding
Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding Open
Purpose We sought to investigate the association between left-sided prosthetic valve dysfunction and gastrointestinal (GI) bleeding. Methods In a retrospective cohort of patients with left-sided prostheses, we identified those who experien…
View article: Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding Short Title: Prosthetic Valve Dysfunction and GI Bleeding
Left-Sided Prosthetic Valve Dysfunction and Gastrointestinal Bleeding Short Title: Prosthetic Valve Dysfunction and GI Bleeding Open
The association between left-sided prosthetic valve (PV) dysfunction and gastrointestinal (GI) bleeding is not well established. In a retrospective cohort of patients with left-sided prostheses, we identified those who experienced one or m…
View article: Invasive therapy versus conservative therapy for patients with stable coronary artery disease: An updated <scp>meta‐analysis</scp>
Invasive therapy versus conservative therapy for patients with stable coronary artery disease: An updated <span>meta‐analysis</span> Open
Background Heart disease remains the leading cause of death in the United States. Although there are clear indications for revascularization in patients with acute coronary syndromes, there is debate regarding the benefits of revasculariza…
View article: Discontinuation and non‐publication of heart failure randomized controlled trials: a call to publish all trial results
Discontinuation and non‐publication of heart failure randomized controlled trials: a call to publish all trial results Open
Aims Discontinuation or non‐publication of trials may hinder scientific progress and violates the commitment made to research participants. We sought to identify the prevalence of discontinuation and non‐publication of heart failure (HF) c…
View article: BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition
BRASH Syndrome with Hyperkalemia: An Under-Recognized Clinical Condition Open
BRASH syndrome is characterized by bradycardia, renal failure, use of an atrioventricular nodal blocker (AVNB), shock, and hyperkalemia. These symptoms represent an ongoing vicious cycle in a patient with a low glomerular filtration rate t…
View article: Elderly Medication Adherence Intervention Using the My Interventional Drug-Eluting Stent Educational App: Multisite Randomized Feasibility Trial
Elderly Medication Adherence Intervention Using the My Interventional Drug-Eluting Stent Educational App: Multisite Randomized Feasibility Trial Open
Background A lifesaving treatment for myocardial infarction is the placement of a stent in a closed or obstructed coronary artery. The largest modifiable risk factor after receiving a stent is medication adherence to Dual AntiPlatelet Ther…
View article: Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk Open
Our meta-analysis indicates that, in the short term, TAVI probably has little or no mortality difference compared to SAVR for severe AS in individuals with low surgical risk. Similarly, there is probably little or no difference in risk of …
View article: Fragility Index in Cardiovascular Randomized Controlled Trials
Fragility Index in Cardiovascular Randomized Controlled Trials Open
Background: Efficacy of an intervention is commonly evaluated using P values, in addition to effect size measures such as absolute risk reduction, relative risk reduction, and numbers needed to treat. However, these measures are not always…
View article: Elderly Medication Adherence Intervention Using the My Interventional Drug-Eluting Stent Educational App: Multisite Randomized Feasibility Trial (Preprint)
Elderly Medication Adherence Intervention Using the My Interventional Drug-Eluting Stent Educational App: Multisite Randomized Feasibility Trial (Preprint) Open
BACKGROUND A lifesaving treatment for myocardial infarction is the placement of a stent in a closed or obstructed coronary artery. The largest modifiable risk factor after receiving a stent is medication adherence to Dual AntiPlatelet The…
View article: Level and Prevalence of Spin in Published Cardiovascular Randomized Clinical Trial Reports With Statistically Nonsignificant Primary Outcomes
Level and Prevalence of Spin in Published Cardiovascular Randomized Clinical Trial Reports With Statistically Nonsignificant Primary Outcomes Open
This study suggests that in reports of cardiovascular RCTs with statistically nonsignificant primary outcomes, investigators often manipulate the language of the report to detract from the neutral primary outcomes. To best apply evidence t…
View article: Assessing the Quality of Abstracts in Randomized Controlled Trials Published in High Impact Cardiovascular Journals
Assessing the Quality of Abstracts in Randomized Controlled Trials Published in High Impact Cardiovascular Journals Open
Background: In the busy world of cardiovascular medicine, abstracts may be the only part of a publication that clinicians read. Therefore, it is critical for abstracts to accurately reflect article content. The extended CONSORT (Consolidat…
View article: Transcatheter versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Transcatheter versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk Open
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the benefits and harms of TAVR compared to SAVR in people with severe AS and low surgical risk.
View article: Percutaneous Mitral Valve Repair versus Optimal Medical Therapy in Patients with Functional Mitral Regurgitation: A Systematic Review and Meta-Analysis
Percutaneous Mitral Valve Repair versus Optimal Medical Therapy in Patients with Functional Mitral Regurgitation: A Systematic Review and Meta-Analysis Open
Objectives . To compare percutaneous mitral valve repair (PMVR) with optimal medical therapy (OMT) in patients with heart failure (HF) and severe functional mitral regurgitation (FMR). Background . Many patients with HF and FMR are not sui…
View article: Artificial Intelligence in Nuclear Cardiology
Artificial Intelligence in Nuclear Cardiology Open
> What we want is a machine that can learn from experience. > > —Alan Turing, London, 1947 The ability to accurately predict future cardiovascular events has been the holy grail of cardiovascular medicine. Thanks to a large body of support…