Rami Saade
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View article: NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer
NOTCH1 Acts as a Tumor Suppressor That Induces Early Differentiation in Head and Neck Cancer Open
We identified frequent inactivating notch1 mutations in HNSCC over a decade ago, indicating its role as a tumor suppressor—unlike its oncogenic function in leukemias and salivary gland tumors. However, there has been much debate in the lit…
Nasal Reshaping Using Barbed Threads Combined With Hyaluronic Acid Filler and Botulinum Toxin A Open
Background Rhinoplasty is a prominent procedure in facial aesthetics, but extended surgical downtime remains its significant limitation. Nonsurgical rhinoplasty has gained popularity as an alternative, offering significant aesthetic improv…
Primary Posterior Neck Hydatid Cyst: A Case Report and Review of the Literature Open
Introduction: Hydatid cyst disease is an endemic parasitic infection caused by Echinococcus granulosus . Hydatid cysts occur mainly in the liver and lungs and are rare in the head and neck region, even in endemic areas. Due to their nonspe…
View article: Data from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma
Data from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Purpose: Aggressive cutaneous squamous cell carcinoma (cSCC) is often a disfiguring and lethal disease. Very little is currently known about the mutations that drive aggressive cSCC.Experimental Design: Whole-exome sequencing was performed…
Supplemental Figures and Methods from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Supplemental Figures S1-S2 and Methods. Figure S1: Mutation types and number by previous radiation treatment. Figure S2: Copy number alterations.
Supplemental Figures and Methods from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Supplemental Figures S1-S2 and Methods. Figure S1: Mutation types and number by previous radiation treatment. Figure S2: Copy number alterations.
Supplemental Tables S1-S4 and S6-S13 from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Supplemental Tables S1-S4 and S6-S13. Supplemental Table S1: Summary of Patient Characteristics. Supplemental Table S2: Patient Characteristics and Key Mutations. Supplemental Table S3: Tumor purity and ploidy calculations. Supplemental Ta…
Supplemental Table S5 from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Supplemental Table S5: mutation annotation file.
Data from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Purpose: Aggressive cutaneous squamous cell carcinoma (cSCC) is often a disfiguring and lethal disease. Very little is currently known about the mutations that drive aggressive cSCC.Experimental Design: Whole-exome sequencing was performed…
Supplemental Tables S1-S4 and S6-S13 from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Supplemental Tables S1-S4 and S6-S13. Supplemental Table S1: Summary of Patient Characteristics. Supplemental Table S2: Patient Characteristics and Key Mutations. Supplemental Table S3: Tumor purity and ploidy calculations. Supplemental Ta…
Supplemental Table S5 from Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma Open
Supplemental Table S5: mutation annotation file.
View article: International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System
International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System Open
Objectives Sinonasal mucosal melanoma (SNMM) is an extremely rare and challenging sinonasal malignancy with a poor prognosis. Standard treatment involves complete surgical resection, but the role of adjuvant therapy remains unclear. Crucia…
Role of<i>CRTC1/MAML2</i>Translocation in the Prognosis and Clinical Outcomes of Mucoepidermoid Carcinoma Open
Detection of the CRTC1/MAML2 fusion transcript provides useful information for MEC diagnosis but is not associated with differences in survival outcomes.