Ramya Sugumar
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View article: Indian medicinal plants as neuroprotective agents in Parkinson’s disease: Bridging tradition and therapeutics
Indian medicinal plants as neuroprotective agents in Parkinson’s disease: Bridging tradition and therapeutics Open
Parkinson’s disease (PD), a progressive neurodegenerative disorder, presents a significant challenge due to its complex etiology and lack of curative treatments. Conventional therapies, primarily dopamine replacement strategies, provide sy…
View article: Comparative evaluation of MPTP and rotenone as inducing agents for Parkinson's disease in adult zebrafish: Behavioural and histopathological insights
Comparative evaluation of MPTP and rotenone as inducing agents for Parkinson's disease in adult zebrafish: Behavioural and histopathological insights Open
Parkinson's disease (PD), a prevalent neurodegenerative disorder, is marked by dopaminergic neuron loss and motor impairments. This study aimed to establish and compare PD models in adult zebrafish using two neurotoxins, MPTP and rotenone,…
View article: Investigation on phytochemical composition, anti-oxidant and anticancer properties of methanolic extract of Phyllanthus niruri schumach & thonn. And protein modelling and drug docking
Investigation on phytochemical composition, anti-oxidant and anticancer properties of methanolic extract of Phyllanthus niruri schumach & thonn. And protein modelling and drug docking Open
The study aims to investigate the Phytochemical Composition, Anti-oxidant and Anticancer properties of methanolic extract of Phyllanthus niruri Schumach & Thonn And the Protein Modelling and drug docking. The research deals with the methan…
View article: Evaluation of Roflumilast (BCRP inhibitor) and Methotrexate (BCRP substrate) on Viability of Primary Squamous Cell Carcinoma – An in vitro Study
Evaluation of Roflumilast (BCRP inhibitor) and Methotrexate (BCRP substrate) on Viability of Primary Squamous Cell Carcinoma – An in vitro Study Open
In this study we evaluated the possible beneficial drug- interaction between Roflumilast (BCRP inhibitor) and Methotrexate (BCRP substrate) on viability of primary squamous cell carcinoma cell line using an in vitro technique. The KB cell …
View article: CCDC 915922: Experimental Crystal Structure Determination
CCDC 915922: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Assessment of Bacterial Load in the Fresh Water Lake System of Tamil Nadu
Assessment of Bacterial Load in the Fresh Water Lake System of Tamil Nadu Open
Microbial study was done on two freshwater systems located in Viluppuram District of Tamil Nadu.Total bacterial density ranged from 6.2 -14.410 7 cfu/lit in Mukaiyur lake and from 5.4 -8.610 6 cfu/lit in Tirukoilur lake.Maximum Total Bac…
View article: Study on Antimicrobial Activity of Algal Isolated from a Freshwater Lake
Study on Antimicrobial Activity of Algal Isolated from a Freshwater Lake Open
To study the antimicrobial activity, algal and cyanobacterial species like Anabaena aequalis, Lyngbya aestuarii, Oscillatoria angusta, Spirulina laxa and Synechocystis aquatilis were selected. Antimicrobial and antifungal activities of alg…
View article: Virtual Screening of Phytochemicals to Novel Target (HAT) Rtt109 in Pneumocystis Jirovecii using Bioinformatics Tools
Virtual Screening of Phytochemicals to Novel Target (HAT) Rtt109 in Pneumocystis Jirovecii using Bioinformatics Tools Open
Baicalin has good binding with Rtt 109 in Pneumocystis jirovecii and can be considered as a novel and valuable treatment option for Pneumocystis pneumonia patients after subjecting it to invivo and invitro studies.