Ramzi Khalil
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View article: Assessing volume status in heart failure: The role of renal duplex ultrasound in evaluating cardiorenal morbidity and heart failure mortality
Assessing volume status in heart failure: The role of renal duplex ultrasound in evaluating cardiorenal morbidity and heart failure mortality Open
Background Critical care physicians face challenges managing decompensated heart failure. This study aims to examine the volume status of patients with decompensated heart failure and evaluate the effectiveness of the renal resistive index…
View article: Benign But Burdensome
Benign But Burdensome Open
A 71-year-old woman presented with dyspnea on exertion. Subsequent evaluation identified lipomatous hypertrophy of the interatrial septum (LHIS), which had findings of hypermetabolic activity owing to the presence of brown fat in the inter…
View article: Evaluation of left ventricular function and volume by two-dimensional echocardiography in a pediatric population: Correlation with cardiac magnetic resonance imaging
Evaluation of left ventricular function and volume by two-dimensional echocardiography in a pediatric population: Correlation with cardiac magnetic resonance imaging Open
Background: Echocardiographic quantification of left ventricular (LV) volume and ejection fraction (EF) is widely used in the pediatric population. However, there is no consensus on the most accurate method of quantifying ventricular volum…
View article: Transmembrane protein <scp>14A</scp> protects glomerular filtration barrier integrity
Transmembrane protein <span>14A</span> protects glomerular filtration barrier integrity Open
Transmembrane protein 14A (TMEM14A) is a relatively unknown protein that is now identified to be required for maintaining the integrity of the glomerular filtration barrier. It is an integral transmembrane protein of 99 amino acids with th…
View article: Management of Postprocedural Conduction Disturbances Using a Prespecified Algorithm in the Optimize PRO Study
Management of Postprocedural Conduction Disturbances Using a Prespecified Algorithm in the Optimize PRO Study Open
Effective management of CDs using a standard algorithm following Evolut TAVR provides similar 30-day safety outcomes to patients without CDs who undergo routine next day discharge. The CD algorithm may provide an effective strategy to reco…
View article: Clinical Impact of Standardized TAVR Technique and Care Pathway
Clinical Impact of Standardized TAVR Technique and Care Pathway Open
The use of the TAVR care pathway and COT resulted in favorable clinical outcomes with no moderate or severe AR and low PPI rates at 30 days while facilitating early discharge and reproducible outcomes across various sites and operators. (O…
View article: Acute Severe Aortic Regurgitation From Catastrophic Pannus Obstruction in a Patient With Mechanical Aortic Valve Replacement
Acute Severe Aortic Regurgitation From Catastrophic Pannus Obstruction in a Patient With Mechanical Aortic Valve Replacement Open
View article: Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier
Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier Open
In this study, the effect of heterozygous germline mutations in the heparan sulfate (HS) glycosaminoglycan chain co-polymerases EXT1 and EXT2 on glomerular barrier function and the endothelial glycocalyx in humans is investigated. Heparan …
View article: Preventing Coronary Obstruction During Transcatheter Aortic Valve Replacement
Preventing Coronary Obstruction During Transcatheter Aortic Valve Replacement Open
View article: Tip-to-Base LAMPOON for Transcatheter Mitral Valve Replacement With a Protected Mitral Annulus
Tip-to-Base LAMPOON for Transcatheter Mitral Valve Replacement With a Protected Mitral Annulus Open
View article: Peer Review #1 of "Overexpression of Myo1e promotes albumin endocytosis by mouse glomerular podocytes mediated by Dynamin (v0.1)"
Peer Review #1 of "Overexpression of Myo1e promotes albumin endocytosis by mouse glomerular podocytes mediated by Dynamin (v0.1)" Open
Background: As a fundamental process internalizing molecules from the plasma membrane, endocytosis plays a crucial role in podocyte biology.Our previous study has identified that overexpression of Myole may enhance podocyte endocytosis.How…
View article: Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos
Glomerular permeability is not affected by heparan sulfate glycosaminoglycan deficiency in zebrafish embryos Open
Proteinuria develops when specific components in the glomerular filtration barrier have impaired function. Although the precise components involved in maintaining this barrier have not been fully identified, heparan sulfate proteoglycans a…
View article: Increased dynamin expression precedes proteinuria in glomerular disease
Increased dynamin expression precedes proteinuria in glomerular disease Open
Dynamin plays an essential role in maintaining the structure and function of the glomerular filtration barrier. Specifically, dynamin regulates the actin cytoskeleton and the turnover of nephrin in podocytes, and knocking down dynamin expr…
View article: Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction
Cystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction Open
View article: A Review of PMMA Bone Cement and Intra‐Cardiac Embolism
A Review of PMMA Bone Cement and Intra‐Cardiac Embolism Open
Percutaneous vertebroplasty procedure is of major importance, given the significantly increasing aging population and the higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex techni…
View article: A Review of PMMA Bone Cement and Intra-Cardiac Embolism
A Review of PMMA Bone Cement and Intra-Cardiac Embolism Open
Percutaneous vertebroplasty procedure is of major importance, given the significant increasing aging population and higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique in…
View article: Perioperative Stress Cardiomyopathy in Simultaneous Liver and Kidney Transplantation: A Call for Early Consideration of Mechanical Circulatory Support
Perioperative Stress Cardiomyopathy in Simultaneous Liver and Kidney Transplantation: A Call for Early Consideration of Mechanical Circulatory Support Open
View article: Severe Acute Traumatic Mitral Regurgitation, Cardiogenic Shock Secondary to Embolized Polymethylmethracrylate Cement Foreign Body After a Percutaneous Vertebroplasty
Severe Acute Traumatic Mitral Regurgitation, Cardiogenic Shock Secondary to Embolized Polymethylmethracrylate Cement Foreign Body After a Percutaneous Vertebroplasty Open
View article: A Unique Case of Successful Mechanical Thrombectomy and Stenting of Cabrol Graft: A Case Report
A Unique Case of Successful Mechanical Thrombectomy and Stenting of Cabrol Graft: A Case Report Open
Cabrol technique and its modification are used as second line or bailout procedure in reimplantation of coronary arteries after aortic root replacement. Percutaneous interventions of Cabrol graft with aspiration thrombectomy and stenting h…
View article: Acute Stent Thrombosis Following Concomitant Balloon Aortic Valvuloplasty and Percutaneous Coronary Intervention
Acute Stent Thrombosis Following Concomitant Balloon Aortic Valvuloplasty and Percutaneous Coronary Intervention Open
Balloon aortic valvuloplasty is often used as a palliative measure or as a bridge to transcatheter aortic valve replacement in the management of aortic stenosis in high risk or inoperable patients. Severe aortic stenosis coexisting with co…
View article: Mechanical Thrombectomy in Post-Transplant Heart
Mechanical Thrombectomy in Post-Transplant Heart Open
Coronary allograft vasculopathy (CAV) is an accelerated form of coronary artery disease that is responsible for significant mortality after cardiac transplantation. We report a case of CAV with significant thrombus burden which was managed…
View article: Transient Mid-Ventricular Ballooning Due to Bad Dream in a Postmenopausal Woman
Transient Mid-Ventricular Ballooning Due to Bad Dream in a Postmenopausal Woman Open
Mid ventricular ballooning syndrome (MBS) was diagnosed in a 55-year-old woman who was admitted to emergency room due to acute chest pain. The trigger for the chest pain was reported as “bad dream” about her husband. MBS, a variant of Tako…
View article: Exclusion of Giant Coronary Artery Aneurysm with Covered Stent Combined with Coil Embolization of Vessel Outflow
Exclusion of Giant Coronary Artery Aneurysm with Covered Stent Combined with Coil Embolization of Vessel Outflow Open
Background: Coronary artery aneurysms (CAA) are rare abnormal dilatation of the coronary arteries. They are termed giant if their diameter exceeds the reference vessel diameter by more than 4 times or if they are more than 8 mm in diameter…
View article: Non-aneurysmal aberrant right subclavian artery causing dysphagia in a young girl: challenges encountered using supraclavicular approach
Non-aneurysmal aberrant right subclavian artery causing dysphagia in a young girl: challenges encountered using supraclavicular approach Open
Aberrant right subclavian artery is the most common anomaly of the aortic arch. Patients are often asymptomatic and discovered accidentally. Occasionally, they present with symptoms related to oesophageal or tracheal compression.A 13-year-…