Hu Wan
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View article: Complete Chloroplast Genome of <i>Enkianthus</i> Lour. (Ericaceae): Comparative Analysis, Phylogenetic Relationships, Divergence History, and Adaptive Evolution
Complete Chloroplast Genome of <i>Enkianthus</i> Lour. (Ericaceae): Comparative Analysis, Phylogenetic Relationships, Divergence History, and Adaptive Evolution Open
Enkianthus (Ericaceae) is a small genus of great ornamental and ecological importance, preferring the specialized habitats in montane elfin forests of east Asia. Here, we for the first time sequenced, assembled, and annotated the complete …
View article: Enhanced Control of Tomato Bacterial Wilt Using a Triple‐Responsive Nanopesticide with Self‐Supplying Reactive Oxygen Species
Enhanced Control of Tomato Bacterial Wilt Using a Triple‐Responsive Nanopesticide with Self‐Supplying Reactive Oxygen Species Open
Tomato production, a vital component of global horticulture, is threatened by bacterial wilt caused by Ralstonia solanacearum . To address this, a triple‐responsive nanoplatform (Ber@MON@CuO 2 @HPC) integrating berberine chloride (Ber), co…
View article: AI-Driven Transcriptome Prediction in Human Pathology: From Molecular Insights to Clinical Applications
AI-Driven Transcriptome Prediction in Human Pathology: From Molecular Insights to Clinical Applications Open
Gene expression regulation underpins cellular function and disease progression, yet its complexity and the limitations of conventional detection methods hinder clinical translation. In this review, we define “predict” as the AI-driven infe…
View article: Upregulation of a cytochrome P450 gene, CYP6B50, confers multi-insecticide resistance in Spodoptera frugiperda
Upregulation of a cytochrome P450 gene, CYP6B50, confers multi-insecticide resistance in Spodoptera frugiperda Open
These results identify CYP6B50 as a key generalist detoxification P450 in S. frugiperda and its role in mediating resistance to multiple insecticides. These findings provide insights into the role of cytochrome P450s in the evolution of in…
View article: Protocol for isolating, culturing, and artificially infecting the Arsenophonus endosymbiont of Nilaparvata lugens
Protocol for isolating, culturing, and artificially infecting the Arsenophonus endosymbiont of Nilaparvata lugens Open
Endosymbionts play a crucial role in insect physiology and adaptation. Here, we present a protocol for isolation, cultivation, and artificial infection of the Arsenophonus endosymbiont of Nilaparvata lugens. We describe steps for symbiont …
View article: Evaluating the biocontrol potential and whole genome sequencing of <i>Pseudomonas fluorescens</i><scp>HT1</scp>: a promising agent against southern blight in <i>Coptis chinensis</i>
Evaluating the biocontrol potential and whole genome sequencing of <i>Pseudomonas fluorescens</i><span>HT1</span>: a promising agent against southern blight in <i>Coptis chinensis</i> Open
BACKGROUND Southern blight, caused by Sclerotium rolfsii , poses a formidable threat to the cultivation of Coptis chinensis , especially affecting both yield and crop quality. Given the environmental harm associated with chemical fungicide…
View article: Cooperative microbial metabolism enhances tryptophan-mediated insecticide detoxification in the fall armyworm
Cooperative microbial metabolism enhances tryptophan-mediated insecticide detoxification in the fall armyworm Open
The fall armyworm, Spodoptera frugiperda, is a major global agricultural pest, known for its rapid evolution of insecticide resistance. Although host genetic adaptation contributes to this trait, the role of gut symbiont-mediated metabolic…
View article: Characterization of <scp><i>CYP303A1</i></scp> and its potential application based on <scp>ZIF</scp>‐8 nanoparticle‐wrapped <scp>dsRNA</scp> in <i>Nilaparvata lugens</i> (<scp>Stål</scp>)
Characterization of <span><i>CYP303A1</i></span> and its potential application based on <span>ZIF</span>‐8 nanoparticle‐wrapped <span>dsRNA</span> in <i>Nilaparvata lugens</i> (<span>Stål</span>) Open
BACKGROUND RNA interference (RNAi) technology has been put forward as a promising method for pest control and resistance management. Mining highly efficient lethal genes and constructing stable double‐stranded RNA (dsRNA) delivery systems …
View article: Insecticide susceptibility in a planthopper pest increases following inoculation with cultured <i>Arsenophonus</i>
Insecticide susceptibility in a planthopper pest increases following inoculation with cultured <i>Arsenophonus</i> Open
Facultative vertically transmitted symbionts are a common feature of insects that determine many aspects of their hosts’ phenotype. Our capacity to understand and exploit these symbioses is commonly compromised by the microbes unculturabil…
View article: Differentiation of Morphological Traits and Genome-Wide Expression Patterns between Rice Subspecies Indica and Japonica
Differentiation of Morphological Traits and Genome-Wide Expression Patterns between Rice Subspecies Indica and Japonica Open
Changes in gene expression patterns can lead to the variation of morphological traits. This phenomenon is particularly evident in recent evolution events such as crop domestication and responses to environmental stress, where alterations i…
View article: Identification of propranolol and derivatives that are chemical inhibitors of phosphatidate phosphatase as potential broad-spectrum fungicides
Identification of propranolol and derivatives that are chemical inhibitors of phosphatidate phosphatase as potential broad-spectrum fungicides Open
Plant diseases cause enormous economic losses in agriculture and threaten global food security, and application of agrochemicals is an important method of crop disease control. Exploration of disease-resistance mechanisms and synthesis of …
View article: Sublethal effects of acetamiprid and afidopyropen on Harmonia axyridis: insights from transcriptomics analysis
Sublethal effects of acetamiprid and afidopyropen on Harmonia axyridis: insights from transcriptomics analysis Open
Evaluating the sublethal effects of insecticide is crucial for protecting and utilizing natural enemies. In this study, we determined the sublethal effects of acetamiprid and afidopyropen on Harmonia axyridis (Pallas) and explored the pote…
View article: Resistance monitoring in field populations of <i>Chilo suppressalis</i> (Lepidoptera: Crambidae) in Hubei Province to four insecticides in 2019–2022
Resistance monitoring in field populations of <i>Chilo suppressalis</i> (Lepidoptera: Crambidae) in Hubei Province to four insecticides in 2019–2022 Open
Chilo suppressalis is a highly destructive insect pest of rice crops. Chemical insecticides have been used as an effective method for controlling this pest. In this study, we evaluated the susceptibility of seven field populations of C. su…
View article: Doxorubicin inhibits phosphatidylserine decarboxylase and confers broad-spectrum antifungal activity
Doxorubicin inhibits phosphatidylserine decarboxylase and confers broad-spectrum antifungal activity Open
Summary As phospholipids of cell membranes, phosphatidylethanolamine (PE) and phosphatidylserine (PS) play crucial roles in glycerophospholipid metabolism. Broadly, some phospholipid biosynthesis enzymes serve as potential fungicide target…
View article: The insecticidal activity and mechanism of tebuconazole on <i>Nilaparvata lugens</i> (Stål)
The insecticidal activity and mechanism of tebuconazole on <i>Nilaparvata lugens</i> (Stål) Open
BACKGROUND Previous studies have shown that fungicides have insecticidal activity that can potentially be used as an insecticide resistance management strategy in the brown planthopper Nilaparvata lugens (Stål). However, the mechanism that…
View article: Insecticide resistance monitoring and diagnostics of resistance mechanisms in cotton-melon aphid, Aphis gossypii Glover in central China
Insecticide resistance monitoring and diagnostics of resistance mechanisms in cotton-melon aphid, Aphis gossypii Glover in central China Open
The data that support the finding of the study: Insecticide resistance monitoring and diagnostics of resistance mechanisms in cotton-melon aphid, Aphis gossypii Glover in central China.
View article: Insecticide resistance monitoring in field populations of Chilo suppressalis Walker (Lepidoptera: Crambidae) from central China
Insecticide resistance monitoring in field populations of Chilo suppressalis Walker (Lepidoptera: Crambidae) from central China Open
Chilo suppressalis Walker (Lepidoptera: Crambidae) is a devastating rice crop pest in China. Chemical insecticides have been used to effectively managing C . suppressalis field populations in most of China’s agricultural regions. However, …
View article: Field Evolution of Insecticide Resistance against Sogatella furcifera (Horváth) in Central China, 2011–2021
Field Evolution of Insecticide Resistance against Sogatella furcifera (Horváth) in Central China, 2011–2021 Open
The white-backed planthopper Sogatella furcifera (Horváth) is an important pest on rice plants throughout Asia. The application of chemical insecticides is still the main approach to suppressing the field population of S. furcifera. Howeve…
View article: RM-SSD: In-Storage Computing for Large-Scale Recommendation Inference
RM-SSD: In-Storage Computing for Large-Scale Recommendation Inference Open
To meet the strict service level agreement requirements of recommendation systems, the entire set of embeddings in recommendation systems needs to be loaded into the memory. However, as the model and dataset for production-scale recommenda…
View article: Insecticide Resistance Monitoring in Field Populations of the Whitebacked Planthopper Sogatella furcifera (Horvath) in China, 2019–2020
Insecticide Resistance Monitoring in Field Populations of the Whitebacked Planthopper Sogatella furcifera (Horvath) in China, 2019–2020 Open
Monitoring is an important component of insecticide resistance management. In this study, resistance monitoring was conducted on 18 field populations in China. The results showed that S. furcifera developed high levels of resistance to chl…
View article: Decline in symbiont-dependent host detoxification metabolism contributes to increased insecticide susceptibility of insects under high temperature
Decline in symbiont-dependent host detoxification metabolism contributes to increased insecticide susceptibility of insects under high temperature Open
The interactions between insects and their bacterial symbionts are shaped by a variety of abiotic factors, including temperature. As global temperatures continue to break high records, a great deal of uncertainty surrounds how agricultural…
View article: Lipolytic Activity of a Carboxylesterase from Bumblebee (Bombus ignitus) Venom
Lipolytic Activity of a Carboxylesterase from Bumblebee (Bombus ignitus) Venom Open
Bee venom is a complex mixture composed of peptides, proteins with enzymatic properties, and low-molecular-weight compounds. Although the carboxylesterase in bee venom has been identified as an allergen, the enzyme’s role as a venom compon…
View article: Transcriptional Response of ATP-Binding Cassette (ABC) Transporters to Insecticide in the Brown Planthopper, Nilaparvata lugens (Stål)
Transcriptional Response of ATP-Binding Cassette (ABC) Transporters to Insecticide in the Brown Planthopper, Nilaparvata lugens (Stål) Open
The ATP-binding cassette (ABC) transporter superfamily is one of the largest groups of proteins and plays a non-negligible role in phase III of the detoxification process, which is highly involved in the response of insects to environmenta…
View article: Correction to: The complexity of climate reconstructions using the coexistence approach on Qinghai–Tibetan Plateau
Correction to: The complexity of climate reconstructions using the coexistence approach on Qinghai–Tibetan Plateau Open
After publication of this article (Zhang et al., 2019), it is noticed the article contains some error:
View article: The complexity of climate reconstructions using the coexistence approach on Qinghai–Tibetan Plateau
The complexity of climate reconstructions using the coexistence approach on Qinghai–Tibetan Plateau Open
Quantifying the palaeoclimates of Qinghai-Tibetan Plateau is vital for understanding the uplift history of plateau and the evolution of Asian monsoon since Cenozoic. Recently, the Coexistence Approach (CA) has been employed to reconstruct …