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View article: Left ventricular strain and chamber dimensions in pediatric sickle cell disease: agerelated reduction in myocardial deformation independent of hemolysis and hydroxyurea therapy
Left ventricular strain and chamber dimensions in pediatric sickle cell disease: agerelated reduction in myocardial deformation independent of hemolysis and hydroxyurea therapy Open
Sickle cell disease (SCD) is associated with cardiovascular complications. Speckle-tracking echocardiography enables early detection of myocardial dysfunction before abnormalities appear in conventional echocardiographic parameters. This s…
View article: Chylothorax: a rare postoperative complication in paediatric cardiac surgery patients – a 15-year retrospective study from a tertiary care centre in a developing country
Chylothorax: a rare postoperative complication in paediatric cardiac surgery patients – a 15-year retrospective study from a tertiary care centre in a developing country Open
Chylothorax, a postoperative complication of CHD surgery, involves chyle accumulation in the pleural cavity, posing challenges in diagnosis and management. This retrospective study investigates the prevalence, aetiology, management, and ou…
View article: Myocarditis Following COVID-19 Vaccine: What Did We Learn?
Myocarditis Following COVID-19 Vaccine: What Did We Learn? Open
The COVID-19 pandemic has had a profound global impact, with vaccination emerging as a key strategy for controlling the virus. However, concerns have arisen regarding potential cardiovascular side effects, particularly myocarditis followin…
View article: Antivirals in COVID‐19: A Focus on Pediatric Cardiac Patients
Antivirals in COVID‐19: A Focus on Pediatric Cardiac Patients Open
The COVID‐19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to p…
View article: Unroofed coronary sinus, left-sided superior vena cava and mitral insufficiency: A case report and review of the literature
Unroofed coronary sinus, left-sided superior vena cava and mitral insufficiency: A case report and review of the literature Open
BACKGROUND Unroofed coronary sinus (UCS) is a rare subtype of atrial septal defect. It is frequently associated with a persistent left superior vena cava and is often part of a more intricate cardiac malformation. CASE SUMMARY This report …
View article: Tetralogy of Fallot With Absent Pulmonary Valve Syndrome: The Experience of a Tertiary Care Center in a Developing Country
Tetralogy of Fallot With Absent Pulmonary Valve Syndrome: The Experience of a Tertiary Care Center in a Developing Country Open
Background Tetralogy of Fallot with an absent pulmonary valve is a very rare variant of tetralogy. It is characterized by absent valve tissue, severe pulmonary regurgitation, and secondary aneurysmal dilatation of the pulmonary arteries. A…
View article: Pulmonary artery banding: a 20-year experience at a tertiary care center in a developing country
Pulmonary artery banding: a 20-year experience at a tertiary care center in a developing country Open
Aim Pulmonary artery banding serves as an important palliative procedure used for the management of several congenital heart lesions. This study aims to describe a 20-year experience of pulmonary artery banding at a tertiary care center in…
View article: NT-proBNP cardiac value in COVID-19: a focus on the paediatric population
NT-proBNP cardiac value in COVID-19: a focus on the paediatric population Open
NT-proBNP is a peptide related to brain natriuretic peptide, a cardiac biomarker and a member of the natriuretic family of peptides. NT-proBNP has demonstrated its clinical utility in the assessment of a wide spectrum of cardiac manifestat…
View article: Hybrid stage 1 palliation for HLHS: the experience of a tertiary center in a developing country
Hybrid stage 1 palliation for HLHS: the experience of a tertiary center in a developing country Open
Background Hypoplastic left heart syndrome (HLHS) accounts for 2.6% of congenital heart disease and is an invariably fatal cardiac anomaly if left untreated. Approximately 33,750 babies are born annually with HLHS in developing countries. …
View article: COVID-19 in congenital heart disease patients: what did we learn?!
COVID-19 in congenital heart disease patients: what did we learn?! Open
Aim COVID-19 pandemic has spread widely at unpreceded pace. Cardiovascular comorbidities are significantly correlated with severe and critical illness. Nevertheless, studies examining the impact of congenital heart disease on COVID-19 seve…
View article: Pathogenesis and distribution of infective endocarditis in the pediatric population: a 20-year experience in a tertiary care center in a developing country
Pathogenesis and distribution of infective endocarditis in the pediatric population: a 20-year experience in a tertiary care center in a developing country Open
Introduction Infective endocarditis is an infection of the endothelial surfaces of the heart. It is more prevalent in adults but its incidence in the pediatric population has been on the rise. The most important factor remains congenital h…
View article: Corticosteroids in COVID-19: pros and cons
Corticosteroids in COVID-19: pros and cons Open
The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden on the global healthcare sector. This necessitated a swift response from the international community to reach a solution. Efforts were made in parallel t…
View article: Low molecular weight heparin in COVID-19: benefits and concerns
Low molecular weight heparin in COVID-19: benefits and concerns Open
Since its emergence, the COVID-19 pandemic had a dramatic impact on the public health worldwide and it scarred the medical, economical, and social determinants of health. Even after the significant vaccination advances, the disease of SARS…
View article: Tamponade and massive pleural effusions secondary to peripherally inserted central catheter in neonates–A complication to be aware of
Tamponade and massive pleural effusions secondary to peripherally inserted central catheter in neonates–A complication to be aware of Open
Background Peripherally inserted central catheters (PICC) are frequently used in neonatal intensive care units (NICU) to assist premature and critically ill neonates. Massive pleural effusions, pericardial effusions, and cardiac tamponade …
View article: Myocarditis in COVID-19: a focus on the pediatric population.
Myocarditis in COVID-19: a focus on the pediatric population. Open
The emergence of the novel SARS-CoV-2 virus in late 2019 introduced new, unpreceded global challenges. Complications arising from COVID-19 widely range from mild to severe and, in some cases, lead to death. The myocardium has proven to be …
View article: COVID-19 IN THE MENA REGION: AN UPDATE
COVID-19 IN THE MENA REGION: AN UPDATE Open
This manuscript is an updated version of a previous study that discusses the status of COVID-19 in the Middle East and North Africa (MENA). It aims to analyze the change in COVID-19 caseload and outcome, as well as the progress in vaccinat…
View article: Pulmonary artery debanding in the cath lab: Lessons learned!
Pulmonary artery debanding in the cath lab: Lessons learned! Open
Background Although primary definitive repair of congenital heart disease has become the preferred management approach, pulmonary artery banding (PAB) remains a valuable palliative procedure used to restrict pulmonary blood flow in certain…
View article: A Massive Ewing Sarcoma of the Rib: A Case Report with Literature Review
A Massive Ewing Sarcoma of the Rib: A Case Report with Literature Review Open
A 9-year-old boy with a 16 cm chest wall mass, presenting with progressive cough and exertional dyspnea, was finally diagnosed with Ewing sarcoma of the rib. Such massive tumors usually present with metastasis and carry a bad prognosis. Fo…
View article: Aspirin in COVID-19: Pros and Cons
Aspirin in COVID-19: Pros and Cons Open
Since its emergence, the COVID-19 pandemic has been ravaging the medical and economic sectors even with the significant vaccination advances. In severe presentations, the disease of SARS-CoV-2 can manifest with life-threatening thromboembo…
View article: The Emerging Role of the Gut Microbiome in the Cancer Response to Immune Checkpoint Inhibitors: A Narrative Review
The Emerging Role of the Gut Microbiome in the Cancer Response to Immune Checkpoint Inhibitors: A Narrative Review Open
The discovery of immune checkpoint inhibitors (ICIs) has revolutionized the care of cancer patients. However, the response to ICI therapy exhibits substantial interindividual variability. Efforts have been directed to identify biomarkers t…
View article: Cardiac Manifestations in COVID-19 Patients: A Focus on the Pediatric Population
Cardiac Manifestations in COVID-19 Patients: A Focus on the Pediatric Population Open
Background. SARS-CoV-2 is a new strain of the coronavirus family that emerged by the end of 2019 and led to the unpreceded COVID-19 pandemic. The virus affects multiple organs simultaneously and leads to a high rate of morbidity and mortal…
View article: COVID-19 in Pediatric Patients: A Focus on CHD Patients
COVID-19 in Pediatric Patients: A Focus on CHD Patients Open
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease represent a sma…
View article: Hydroxychloroquine in COVID-19 Patients: Pros and Cons
Hydroxychloroquine in COVID-19 Patients: Pros and Cons Open
The pandemic of COVID-19, caused by SARS-CoV-2, has recently overwhelmed medical centers and paralyzed economies. The unparalleled public distress caused by this pandemic mandated an urgent quest for an effective approach to manage or trea…