Randa Taher
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View article: Bezafibrate for severe refractory intrahepatic cholestasis of pregnancy: a case report and literature review
Bezafibrate for severe refractory intrahepatic cholestasis of pregnancy: a case report and literature review Open
This case highlights a rare, severe, and treatment-refractory presentation of ICP. The marked improvement following bezafibrate supports its potential as a therapeutic consideration in similar high-risk cases. Further research is needed to…
View article: Reduced Predictive Performance of the <scp>FIB</scp>‐4 Index in Chronic Hepatitis B Patients With Concurrent Metabolic Dysfunction‐Associated Liver Disease
Reduced Predictive Performance of the <span>FIB</span>‐4 Index in Chronic Hepatitis B Patients With Concurrent Metabolic Dysfunction‐Associated Liver Disease Open
The coexistence of chronic hepatitis B (CHB) and metabolic dysfunction–associated liver disease (MASLD) gained recognition, but the diagnostic performance of non‐invasive markers regarding it remains underexplored. This study aimed to eval…
View article: Establishing the Clinical Utility of Glucagon-Enhanced MRCP for Improved Hepatopancreatobiliary Assessment
Establishing the Clinical Utility of Glucagon-Enhanced MRCP for Improved Hepatopancreatobiliary Assessment Open
Background: Magnetic Resonance Cholangiopancreatography (MRCP) has continuously evolved to enhance visualization capabilities. However, diagnosing biliary ductal system pathology, particularly early primary sclerosing cholangitis (PSC), re…
View article: Serrated polyps in colorectal cancer prevention: prevalence, characteristics and clinical insights from a large retrospective cohort study
Serrated polyps in colorectal cancer prevention: prevalence, characteristics and clinical insights from a large retrospective cohort study Open
This study highlights our practice's low detection rate of serrated polyps, emphasizing the need for increased awareness and improved diagnostic practices. The high prevalence of flat lesions and elevated rates of dysplasia underscore the …
View article: Prevalence and Risk Factors of Type 2 Diabetes Mellitus Among Hepatitis B Virus Patients: A Large Retrospective Cohort Study
Prevalence and Risk Factors of Type 2 Diabetes Mellitus Among Hepatitis B Virus Patients: A Large Retrospective Cohort Study Open
Background: Hepatitis B virus (HBV) infection and type 2 diabetes mellitus (T2DM) are both major health burdens worldwide. There is a suspected link between the two conditions, but the nature of the relationship is not well understood. Thi…
View article: Characterizing Unique Clinical and Virological Profiles in Concurrent Chronic Hepatitis B and Metabolic Dysfunction-Associated Liver Disease: Insights from a Population-Based Cohort Study
Characterizing Unique Clinical and Virological Profiles in Concurrent Chronic Hepatitis B and Metabolic Dysfunction-Associated Liver Disease: Insights from a Population-Based Cohort Study Open
Background: The concurrent presence of chronic hepatitis B virus (CHB) infection and metabolic dysfunction-associated steatotic liver disease (MASLD) presents a unique clinical scenario with implications that are not yet fully understood. …
View article: Gastroscopy Yield in the Young: Comprehensive Assessment of Endoscopic and Histologic Findings—A Comparative Study
Gastroscopy Yield in the Young: Comprehensive Assessment of Endoscopic and Histologic Findings—A Comparative Study Open
Background. The escalating utilization of gastroscopy in young individuals necessitates an in-depth examination of its diagnostic yield and outcomes in this population. This study aims to investigate and compare various aspects of gastrosc…
View article: The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome
The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome Open
Background: Chronic constipation, a prevalent gastrointestinal complaint, exhibits rising incidence and diverse clinical implications, especially among the aging population. This study aims to assess colonoscopy performance in chronic cons…
View article: Screening and Colonoscopy Quality Measures: Ethnic Disparities and Impact on Patients’ Outcome
Screening and Colonoscopy Quality Measures: Ethnic Disparities and Impact on Patients’ Outcome Open
Background. Recent reports have confirmed the improving trends in colorectal cancer (CRC) incidence and outcomes. Still, disparities in incidence and mortality in CRC continue to persist between major ethnic groups despite the provision of…
View article: Human Neutrophil α-Defensins 1–3 Are Upregulated in the Microenvironment of Fibrotic Liver
Human Neutrophil α-Defensins 1–3 Are Upregulated in the Microenvironment of Fibrotic Liver Open
Background and Objectives: Neutrophil infiltration is an established signature of Non-Alcoholic Fatty Liver Disease (NAFLD) and Steatohepatitis (NASH). The most abundant neutrophilic peptide, alpha-defensin, is considered a new evolving ri…
View article: Pulmonary embolism risk in hospitalized patients with nonalcoholic fatty liver disease: A case-control study
Pulmonary embolism risk in hospitalized patients with nonalcoholic fatty liver disease: A case-control study Open
Abundant research has associated nonalcoholic fatty liver disease (NAFLD) with atherosclerosis, but very few reports have evaluated the association between NAFLD and venous thromboembolism. We aimed to investigate the association between N…
View article: Predictors of Clinical Course and Outcomes of Acute Diverticulitis: The Role of Age and Ethnicity
Predictors of Clinical Course and Outcomes of Acute Diverticulitis: The Role of Age and Ethnicity Open
Background and Objectives: Acute diverticulitis (AD) is the leading and most burdensome complication of colonic diverticulosis. However, risk factors for its development and predictors of its course are still poorly defined. In this regard…
View article: Differentiation between myopericarditis and acute myocardial infarction on presentation in the emergency department using the admission C-reactive protein to troponin ratio
Differentiation between myopericarditis and acute myocardial infarction on presentation in the emergency department using the admission C-reactive protein to troponin ratio Open
Background The treatment of myopericarditis is different than that of acute myocardial infarction (AMI). However, since their clinical presentation is frequently similar it may be difficult to distinguish between these entities despite a d…
View article: The c- reactive protein to troponin ratio enhances the differentiation of perimyocarditis from acute myocardial infarction
The c- reactive protein to troponin ratio enhances the differentiation of perimyocarditis from acute myocardial infarction Open
Funding Acknowledgements Type of funding sources: None. Differentiating perimyocarditis from acute myocardial infarction (AMI) is frequently difficult . Perimyocarditis is primarily an inflammatory disease associated with high C-reactive p…
View article: Acute complicated diverticulitis is associated with an increased advanced neoplasia diagnosis rate
Acute complicated diverticulitis is associated with an increased advanced neoplasia diagnosis rate Open
Recent reports have documented an unchanged rate of occurrence of colorectal cancer (CRC) and have publicised doubts regarding the benefit of prompt colonoscopy procedures after an episode of acute diverticulitis (AD). These reports mandat…
View article: A rare case of adult colocolonic intussusception of the descending colon
A rare case of adult colocolonic intussusception of the descending colon Open
A 28-year-old woman approached the emergency department because of recent diffuse abdominal pain and diarrhoea. Peritoneal signs on physical exam led to abdominal CT scan which demonstrated colonic obstruction, resulting from colocolonic i…