Randall W. Brown
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View article: The Role of Depression in Pain Coping and Opioid Use in Traumatic Injury Patients
The Role of Depression in Pain Coping and Opioid Use in Traumatic Injury Patients Open
View article: M15 Quantification of clinical deterioration of asthma based on threshold for SABA use in two studies of the digihaler system
M15 Quantification of clinical deterioration of asthma based on threshold for SABA use in two studies of the digihaler system Open
Background In two studies of the Digihaler System (DS), patients with suboptimally controlled asthma used an albuterol inhaler with an integrated sensor that objectively recorded real-time reliever use. US asthma experts, through a modifie…
View article: Impact of the COVID-19 Pandemic on Outcomes of CAPTURE: A Primary Care Chronic Obstructive Pulmonary Disease Screening Clinical Trial
Impact of the COVID-19 Pandemic on Outcomes of CAPTURE: A Primary Care Chronic Obstructive Pulmonary Disease Screening Clinical Trial Open
"Impact of the SARS-CoV-2 Pandemic on Outcomes of CAPTURE; a Primary Care COPD Screening Study." Annals of the American Thoracic Society, 0(ja), pp.
View article: Discriminative Accuracy of the CAPTURE Tool for Identifying Chronic Obstructive Pulmonary Disease in US Primary Care Settings
Discriminative Accuracy of the CAPTURE Tool for Identifying Chronic Obstructive Pulmonary Disease in US Primary Care Settings Open
Importance Chronic obstructive pulmonary disease (COPD) is underdiagnosed in primary care. Objective To evaluate the operating characteristics of the CAPTURE (COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and …
View article: A Predictive Machine Learning Tool for Asthma Exacerbations: Results from a 12-Week, Open-Label Study Using an Electronic Multi-Dose Dry Powder Inhaler with Integrated Sensors
A Predictive Machine Learning Tool for Asthma Exacerbations: Results from a 12-Week, Open-Label Study Using an Electronic Multi-Dose Dry Powder Inhaler with Integrated Sensors Open
A machine learning model to predict impending asthma exacerbations using data from the eMDPI was successfully developed. This approach may support a shift from reactive care to proactive, preventative, and personalized management of chroni…
View article: Effectiveness of a Digital Inhaler System for Patients With Asthma: A 12-Week, Open-Label, Randomized Study (CONNECT1)
Effectiveness of a Digital Inhaler System for Patients With Asthma: A 12-Week, Open-Label, Randomized Study (CONNECT1) Open
In this study, participants using the RDS had greater odds of clinically meaningful improvements in asthma control versus SoC after 3 months. Further investigation of the potential of the RDS to help improve asthma management is warranted.
View article: Assessment of Real-World Escalation to Biologics in US Patients With Asthma
Assessment of Real-World Escalation to Biologics in US Patients With Asthma Open
In this study, most patients initiating biologic therapy had mild-to-moderate asthma or suboptimal maintenance medication adherence, possibly indicating inappropriate escalation. Incorporating objective medication adherence monitoring into…
View article: COVID-19 DATA FROM THE PRIMARY CARE POPULATION OF THE CAPTURE STUDY
COVID-19 DATA FROM THE PRIMARY CARE POPULATION OF THE CAPTURE STUDY Open
View article: Short-Acting Beta-Agonist Bursts and Overuse in Patients with Poorly Controlled Asthma, as Recorded by a Digital Inhaler
Short-Acting Beta-Agonist Bursts and Overuse in Patients with Poorly Controlled Asthma, as Recorded by a Digital Inhaler Open
View article: Chronic Obstructive Pulmonary Disease Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE): Multi-Method Qualitative Findings Support Implementation Readiness of a New COPD Screening Tool in Primary Care Practice
Chronic Obstructive Pulmonary Disease Assessment in Primary Care to Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE): Multi-Method Qualitative Findings Support Implementation Readiness of a New COPD Screening Tool in Primary Care Practice Open
Rationale: Enhancing COPD management should include optimal disease recognition at the primary care level. As effective COPD diagnosis may involve all levels of primary care clinic staff, the CAPTURE validation study included workflow revi…
View article: Digital Health Technology in Asthma: A Comprehensive Scoping Review
Digital Health Technology in Asthma: A Comprehensive Scoping Review Open
Digital health interventions show substantial promise for asthma disease monitoring and personalization of treatment. To be successful, future interventions will need to include both inhaler device and software elements, combining accurate…
View article: Protocol Summary of the COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE) Validation in Primary Care Study
Protocol Summary of the COPD Assessment in Primary Care To Identify Undiagnosed Respiratory Disease and Exacerbation Risk (CAPTURE) Validation in Primary Care Study Open
Chronic obstructive pulmonary disease (COPD) often remains undiagnosed and untreated. To date, COPD screening/case finding has not been designed to identify clinically significant COPD, disease ready for therapies beyond smoking ces…
View article: REMOTELY RECORDED PEAK INHALATION FLOW PATTERNS AMONG PATIENTS WITH COPD USING PROAIR DIGIHALER FOR RESCUE MEDICATION
REMOTELY RECORDED PEAK INHALATION FLOW PATTERNS AMONG PATIENTS WITH COPD USING PROAIR DIGIHALER FOR RESCUE MEDICATION Open
View article: Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide
Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide Open
View article: Can CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment?
Can CAPTURE be used to identify undiagnosed patients with mild-to-moderate COPD likely to benefit from treatment? Open
CAPTURE (450/350) may be useful for identifying symptomatic patients with mild-to-moderate airflow obstruction in need of diagnostic evaluation for COPD.
View article: A randomized clinical trial of a culturally responsive intervention for African American women with asthma
A randomized clinical trial of a culturally responsive intervention for African American women with asthma Open
View article: Impact of Goal Setting and Goal Attainment Methods on Asthma Outcomes
Impact of Goal Setting and Goal Attainment Methods on Asthma Outcomes Open
Optimal use of goal-setting strategies in self-management efforts with high-risk individuals with asthma is not well understood. This study aimed to describe factors associated with goal attainment in an asthma self-management intervention…
View article: Plerixafor Used in a “Just in Time” Fashion Allows Timely Autologous Hematopoietic Cell Transplant (HCT) in Patients Who Are at High Risk for Inadequate Apheresis
Plerixafor Used in a “Just in Time” Fashion Allows Timely Autologous Hematopoietic Cell Transplant (HCT) in Patients Who Are at High Risk for Inadequate Apheresis Open
One of the challenges for autologous HCT is the ability to collect an adequate number of progenitor cells in patients with limited hematopoietic reserve. We prospectively explored the ability of plerixafor, a CXCR4 inhibitor, when used in …
View article: Asthma Patient Education: Partnership in Care
Asthma Patient Education: Partnership in Care Open
Background Asthma education is a necessary and critical component of asthma management. Methods A review of the most‐to‐date global and national (US) guidelines and standards provides the basis for this concise asthma education primer. Res…
View article: Poor Peripheral Blood Stem Cell Mobilization Correlates with Worse Long-Term Outcomes in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Poor Peripheral Blood Stem Cell Mobilization Correlates with Worse Long-Term Outcomes in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation Open
Poor peripheral blood stem cell (PBSC) mobilization has been shown to be associated with worse outcomes in lymphoma patients undergoing autologous stem cell transplantation (ASCT). The impact of poor mobilization on the outcome of ASCT in …