Rangrang Wang
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View article: The Anxiolytic Drug Tandospirone Enhances Cisplatin Efficacy by Reducing Tumor Cell Cholesterol Levels: Dual Roles in Emotional Distress Management and Chemosensitization for NSCLC Patients
The Anxiolytic Drug Tandospirone Enhances Cisplatin Efficacy by Reducing Tumor Cell Cholesterol Levels: Dual Roles in Emotional Distress Management and Chemosensitization for NSCLC Patients Open
Patients undergoing lung cancer surgery face a significantly increased risk of emotional distress (ED), including anxiety and depression. This distress not only severely impairs their quality of life but may also negatively affect treatmen…
View article: Impact of varied immunosuppressive agents and post-transplant diabetes mellitus on prognosis among diverse transplant recipients (experimental studies)
Impact of varied immunosuppressive agents and post-transplant diabetes mellitus on prognosis among diverse transplant recipients (experimental studies) Open
The success of solid organ transplantation (SOT) and the use of immunosuppressive agents offer hope to patients with end-stage diseases. However, the impact of post-transplant diabetes mellitus (PTDM) on SOT patients has become increasingl…
View article: A prognostic nomogram integrating carcinoembryonic antigen levels for predicting overall survival in elderly patients with stage II–III colorectal cancer
A prognostic nomogram integrating carcinoembryonic antigen levels for predicting overall survival in elderly patients with stage II–III colorectal cancer Open
We constructed a prediction nomogram for stage II-III elderly CRC patients by combining pre-treatment carcinoembryonic antigen (CEA) levels, which can accurately predict patient survival. This facilitates clinicians to accurately assess pa…
View article: FEN1 Promotes Hepatocellular Carcinoma Progression by Activating Cell Cycle Transition from G2 To M Phase
FEN1 Promotes Hepatocellular Carcinoma Progression by Activating Cell Cycle Transition from G2 To M Phase Open
Flap endonuclease 1 (FEN1) is a structure-specific nuclease that is involved in the occurrence and development of various types of tumors. Previous studies have shown that FEN1 plays an important role in the development of hepatocellular c…
View article: Prognostic value of E‑26 transformation‑specific‑related gene in prostate cancer based on immunohistochemistry analysis
Prognostic value of E‑26 transformation‑specific‑related gene in prostate cancer based on immunohistochemistry analysis Open
E-26 transformation-specific-related gene (ERG) has been implicated in prostate cancer; however, its prognostic role remains unclear. Therefore, the present study aimed to investigate the association of ERG with the prognosis after radical…
View article: Impact of Varied Immunosuppressive Agents and Posttransplant Diabetes Mellitus on Prognosis Among Diverse Transplant Recipients
Impact of Varied Immunosuppressive Agents and Posttransplant Diabetes Mellitus on Prognosis Among Diverse Transplant Recipients Open
View article: Role of DTL in Hepatocellular Carcinoma and Its Impact on the Tumor Microenvironment
Role of DTL in Hepatocellular Carcinoma and Its Impact on the Tumor Microenvironment Open
Background The crucial role of DTL has been previously implicated in genomic stability; however, its prognostic value and its relation with tumor immunity in hepatocellular carcinoma (HCC) remain to be further explored. Methods Transcripti…
View article: TOP2A promotes proliferation and metastasis of hepatocellular carcinoma regulated by miR-144-3p
TOP2A promotes proliferation and metastasis of hepatocellular carcinoma regulated by miR-144-3p Open
Topoisomerase II alpha (TOP2A) is an important nuclear protein which is found in various types of cancers. Whether TOP2A plays an important role in hepatocellular carcinoma (HCC) remains unclear. Through bioinformatic analysis and clinical…
View article: Estradiol is significantly associated with prognosis in non-surgical liver cancer patients: from bench to bedside
Estradiol is significantly associated with prognosis in non-surgical liver cancer patients: from bench to bedside Open
There are rarely systematic studies to analyze the prognostic factors among non-surgical liver cancer patients. Whether there is a gender difference in the survival of non-surgical liver cancer patients and what may cause this difference i…
View article: USP11 induce resistance to 5-Fluorouracil in Colorectal Cancer through activating autophagy by stabilizing VCP
USP11 induce resistance to 5-Fluorouracil in Colorectal Cancer through activating autophagy by stabilizing VCP Open
Chemotherapy plays an important role in the treatment of patients with colorectal cancer (CRC). However, the resistance to chemotherapy severely affects the prognosis of CRC patients and the mechanisms are still poorly understood. Our stud…
View article: Primary pulmonary diffuse large B-cell lymphoma with multiple ground-glass nodules as the primary manifestation
Primary pulmonary diffuse large B-cell lymphoma with multiple ground-glass nodules as the primary manifestation Open
Introduction: Primary pulmonary lymphoma (PPL) is a rare extranodal lymphoma. Only 5% to 20% of patients suffering from PPL have diffuse large β-cell lymphoma (DLBCL), and their chest computed tomography (CT) findings show single- or doubl…
View article: USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway
USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway Open
USP11 promoted tumor growth and metastasis in CRC via the ERK/MAPK pathway by stabilizing PPP1CA, suggesting USP11 is a potential prognostic marker. FUND: This work was supported by National Natural Science Foundation of China (NSFC8153004…
View article: Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway
Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway Open
Little is known about the function of Keratin 80 (KRT80), an epithelial keratin, in cancer. This study investigated the role of KRT80 in the prognosis of colorectal carcinoma (CRC) and the underlying mechanisms involved in CRC migration an…