Ranjana Pal
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View article: Ascorbic acid modulates immune responses through Jumonji‐C domain containing histone demethylases and Ten eleven translocation (TET) methylcytosine dioxygenase
Ascorbic acid modulates immune responses through Jumonji‐C domain containing histone demethylases and Ten eleven translocation (TET) methylcytosine dioxygenase Open
Ascorbic acid is a redox regulator in many physiological processes. Besides its antioxidant activity, many intriguing functions of ascorbic acid in the expression of immunoregulatory genes have been suggested. Ascorbic acid acts as a co‐fa…
View article: CCDC 2177825: Experimental Crystal Structure Determination
CCDC 2177825: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2177824: Experimental Crystal Structure Determination
CCDC 2177824: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Supplementation of L-ascorbic acid and α-tocopherol alleviate arsenic induced immunotoxicities in thymus and spleen by dwindling oxidative stress induced inflammation
Supplementation of L-ascorbic acid and α-tocopherol alleviate arsenic induced immunotoxicities in thymus and spleen by dwindling oxidative stress induced inflammation Open
Herein, we investigated whether L-ascorbic acid and α-tocopherol supplementation has potential to alleviate arsenic induced immunotoxicities in thymus, spleen and circulating leukocytes. Forty-eight adult male Wistar rats were randomly div…
View article: Enhanced expression of death receptor 5 is responsible for increased cytotoxicity of theophylline in combination with recombinant human TRAIL in MDA-MB-231 breast cancer cells
Enhanced expression of death receptor 5 is responsible for increased cytotoxicity of theophylline in combination with recombinant human TRAIL in MDA-MB-231 breast cancer cells Open
Background: Theophylline has been reported to induce cytotoxicity and cell cycle arrest in cancer cells. On the other hand, TRAIL, a secretory ligand, is known for its unique ability to induce cell death only in tumor cells. In the present…
View article: A Descriptive Study on Prevalence of Occupational Health Hazards among Employees of Selected Sugarcane Factory in Deharadun, Uttarakhand
A Descriptive Study on Prevalence of Occupational Health Hazards among Employees of Selected Sugarcane Factory in Deharadun, Uttarakhand Open
Occupational health hazards have deleterious effect on the individual health and safety as well as the organizational effectiveness.Emerging occupational health problems are to be tackled along with existing public health problems like com…
View article: CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage
CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage Open
CUX1 and CUX2 proteins are characterized by the presence of three highly similar regions called Cut repeats 1, 2, and 3. Although CUX1 is ubiquitously expressed, CUX2 plays an important role in the specification of neuronal cells and conti…
View article: The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts
The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts Open
Despite having long telomeres, mouse embryo fibroblasts (MEFs) senesce more rapidly than human diploid fibroblasts because of the accumulation of oxidative DNA damage. The CUX1 homeodomain protein was recently found to prevent senescence i…