Ranran Chen
YOU?
Author Swipe
View article: Correction: Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis
Correction: Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis Open
[This corrects the article DOI: 10.3389/fnagi.2025.1522073.].
View article: STING regulates NETs formation by activating GSDMD in influenza viral pneumonia
STING regulates NETs formation by activating GSDMD in influenza viral pneumonia Open
Background Viral pneumonia is the most common and lethal pandemic disease, but there are no broad-spectrum antiviral drugs with high genetic barriers to resistance. To elucidate the mechanisms of viral pneumonia progression and potential t…
View article: Polymethoxyflavones extracted from Bauhinia championii alleviate LPS-induced acute lung injury by ameliorating endoplasmic reticulum stress
Polymethoxyflavones extracted from Bauhinia championii alleviate LPS-induced acute lung injury by ameliorating endoplasmic reticulum stress Open
Background Acute lung injury (ALI), a critical respiratory condition, often escalates into acute respiratory distress syndrome, which is associated with significant morbidity and mortality. Bauhinia championii , a botanical drug used in tr…
View article: Effect of aspartic acid on the hydration process and setting performance of hemihydrate gypsum under alkaline conditions
Effect of aspartic acid on the hydration process and setting performance of hemihydrate gypsum under alkaline conditions Open
This study employs Ca(OH)2 (CH) as an alkaline regulator to adjust the pH of β-hemihydrate gypsum (β-HH), and l-aspartic acid (LA) as a retarder. The effects of LA on the hydration performance of β-HH under different alkaline conditions we…
View article: Skin pathology in ALS: Diagnostic implications and biomarker potential
Skin pathology in ALS: Diagnostic implications and biomarker potential Open
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of motor neurons in the spinal cord and brain, resulting in motor deficits and muscle atrophy. Approximately 5–10% of ALS patients are famil…
View article: Morus alba L. alleviates influenza viral pneumonia. Evidences of its mechanism of action
Morus alba L. alleviates influenza viral pneumonia. Evidences of its mechanism of action Open
MLE can alleviate PR8-induced viral pneumonia through inhibiting the Dectin-1/Syk pathway.
View article: Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis
Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis Open
Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons (MNs). Genetic mutations in Optineurin (OPTN) and Superoxide Dismutase 1 (SOD1) have been identified as causal facto…
View article: Baddeleyite <scp>SK10</scp>‐3: A Natural Reference Material for Microbeam U‐Pb Geochronology and Hf Isotopic Measurements
Baddeleyite <span>SK10</span>‐3: A Natural Reference Material for Microbeam U‐Pb Geochronology and Hf Isotopic Measurements Open
Baddeleyite is an important U‐Pb geochronometer and Hf isotope tracer that commonly occurs as an accessory phase in silica‐undersaturated igneous rocks of terrestrial and extra‐terrestrial origin. Currently, very few well‐characterised, la…
View article: Corrigendum: Predicting 24-hour intraocular pressure peaks and averages with machine learning
Corrigendum: Predicting 24-hour intraocular pressure peaks and averages with machine learning Open
[This corrects the article DOI: 10.3389/fmed.2024.1459629.].
View article: Machine Learning Models for Predicting 24-Hour Intraocular Pressure Changes: A Comparative Study
Machine Learning Models for Predicting 24-Hour Intraocular Pressure Changes: A Comparative Study Open
BACKGROUND Predicting 24-hour intraocular pressure (IOP) fluctuations is crucial for enhancing glaucoma management. Traditional methods of measuring 24-hour IOP fluctuations are complex and present certain limitations. The present study le…
View article: Physical‐Matched Nanoplatelets Boost Heterogeneous Thrombi Targeting Through Self‐Adaptive Deformation for Thrombolysis and Endothelial Repairing
Physical‐Matched Nanoplatelets Boost Heterogeneous Thrombi Targeting Through Self‐Adaptive Deformation for Thrombolysis and Endothelial Repairing Open
The heterogeneity of thrombi in terms of composition, structure, and blood rheology parameters presents a challenge for effective thrombus‐targeting drug delivery. To address this, a self‐adaptive nano‐delivery system, termed D‐PLT, is dev…
View article: Predicting 24-hour intraocular pressure peaks and averages with machine learning
Predicting 24-hour intraocular pressure peaks and averages with machine learning Open
Purpose Predicting 24-hour peak and average intraocular pressure (IOP) is essential for the diagnosis and management of glaucoma. This study aimed to develop and assess a machine learning model for predicting 24-hour peak and average IOP, …
View article: Full-mouth rehabilitation with lithium disilicate ceramic crowns in hypoplastic amelogenesis imperfecta: a case report and review of literature
Full-mouth rehabilitation with lithium disilicate ceramic crowns in hypoplastic amelogenesis imperfecta: a case report and review of literature Open
Patients with severe hypoplastic AI require proper full-mouth rehabilitation. Using full-crown lithium disilicate restorations to increase the OVD by 2‒4 mm is a safe and predictable recommendation for such cases. In addition, patients wit…
View article: Boron Neutron Capture Therapy‐Derived Extracellular Vesicles via DNA Accumulation Boost Antitumor Dendritic Cell Vaccine Efficacy
Boron Neutron Capture Therapy‐Derived Extracellular Vesicles via DNA Accumulation Boost Antitumor Dendritic Cell Vaccine Efficacy Open
Radiated tumor cell‐derived extracellular vesicles (RT‐EVs) encapsulate abundant DNA fragments from irradiated tumor cells, in addition to acting as integrators of multiple tumor antigens. Accumulating evidence indicates these DNA fragment…
View article: Effect of Composition Characteristics on Mechanical Properties of UHPMC Based on Response Surface Methodology and Acoustic Emission Monitoring
Effect of Composition Characteristics on Mechanical Properties of UHPMC Based on Response Surface Methodology and Acoustic Emission Monitoring Open
Manufactured sand (MS) is a promising alternative aggregate to quartz sand (QS) in ultra-high-performance concrete (UHPC) in the preparation of ultra-high-performance manufactured sand concrete (UHPMC), which possesses the characteristics …
View article: Study of Molecular Dimer Morphology Based on Organic Spin Centers: Nitronyl Nitroxide Radicals
Study of Molecular Dimer Morphology Based on Organic Spin Centers: Nitronyl Nitroxide Radicals Open
In this work, in order to investigate the short-range interactions between molecules, the spin-magnetic unit nitronyl nitroxide (NN) was introduced to synthesize self-assembly single radical molecules with hydrogen bond donors and acceptor…
View article: A novel shockwave-driven nanomotor composite microneedle transdermal delivery system for the localized treatment of osteoporosis: a basic science study
A novel shockwave-driven nanomotor composite microneedle transdermal delivery system for the localized treatment of osteoporosis: a basic science study Open
Background: Clinical protocols in osteoporosis treatment could not meet the requirement of increasing local bone mineral density. A local delivery system was brought in to fix this dilemma. The high-energy extracorporeal shock wave (ESW) c…
View article: Application of recombinase polymerase amplification with <scp>CRISPR</scp>/Cas12a and multienzyme isothermal rapid amplification with lateral flow dipstick assay for <scp><i>Bactrocera correcta</i></scp>
Application of recombinase polymerase amplification with <span>CRISPR</span>/Cas12a and multienzyme isothermal rapid amplification with lateral flow dipstick assay for <span><i>Bactrocera correcta</i></span> Open
BACKGROUND Bactrocera correcta is a quarantine pest that negatively impacts the fruit and vegetable industry. Differentiating B. correcta from similar species, especially in non‐adult stages, remains challenging. Rapid molecular identifica…
View article: Close-packed nitronyl nitroxide radicals by Au–S self-assembly: strong ferromagnetic coupling
Close-packed nitronyl nitroxide radicals by Au–S self-assembly: strong ferromagnetic coupling Open
Organic radicals (nitronyl nitroxide) modified AuNPs based on Au–S self-assembly exhibit strong ferromagnetic coupling (spin interactions).
View article: Fundamental roles of the Optineurin gene in the molecular pathology of Amyotrophic Lateral Sclerosis
Fundamental roles of the Optineurin gene in the molecular pathology of Amyotrophic Lateral Sclerosis Open
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons (MNs) in the brain and spinal cord. It is caused by multiple factors, including mutations in any one of several speci…
View article: Predicting 24-hour Intraocular Pressure Fluctuations using Machine Learning: A Retrospective Analysis
Predicting 24-hour Intraocular Pressure Fluctuations using Machine Learning: A Retrospective Analysis Open
24-hour intraocular pressure fluctuation is at a risk of glaucomatous progression. We thus aimed to develop a machine learning-based predictive model for 24-hour intraocular pressure (IOP) fluctuation. It was a retrospective analysis of el…
View article: Quarantine Disinfestation of Papaya Mealybug, Paracoccus marginatus (Hemiptera: Pseudococcidae) Using Gamma and X-rays Irradiation
Quarantine Disinfestation of Papaya Mealybug, Paracoccus marginatus (Hemiptera: Pseudococcidae) Using Gamma and X-rays Irradiation Open
Paracoccus marginatus is a highly polyphagous invasive pest that poses a significant quarantine threat to tropical and subtropical countries. Infested commodities in international trade should undergo phytosanitary treatment, and irradiati…
View article: Quarantine Disinfestation of Papaya Mealybug (Hemiptera: Pseudococcidae) Using Gamma and X-rays Irradiation
Quarantine Disinfestation of Papaya Mealybug (Hemiptera: Pseudococcidae) Using Gamma and X-rays Irradiation Open
The papaya mealybug Paracoccus marginatus is an invasive, polyphagous pest and poses a quarantine threat to tropical and subtropical countries. Infested commodity internationally should be undergoing phytosanitary treatment, while irradiat…
View article: Quarantine Disinfestation of Papaya Mealybug (Hemiptera: Pseudococcidae) Using Gamma and X-rays Irradiation
Quarantine Disinfestation of Papaya Mealybug (Hemiptera: Pseudococcidae) Using Gamma and X-rays Irradiation Open
The papaya mealybug Paracoccus marginatus is an invasive, polyphagous pest and poses a quarantine threat to tropical and subtropical countries. Infested commodity internationally should be undergoing phytosanitary treatment, while irradiat…