Raphaëlle Youf
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View article: Direct ink writing of sustainable multifunctional biodegradable porous Fe-eggshell scaffolds
Direct ink writing of sustainable multifunctional biodegradable porous Fe-eggshell scaffolds Open
Medical devices contribute to the carbon footprint generated by the healthcare sector. The development of implants and biomaterials using recycled waste materials promotes sustainable advances in tissue engineering. Additively manufactured…
View article: The (re)emergence of aerosol delivery: Treatment of pulmonary diseases and its clinical challenges
The (re)emergence of aerosol delivery: Treatment of pulmonary diseases and its clinical challenges Open
Aerosol delivery represents a rapid and non-invasive way to directly reach the lungs while escaping the hepatic first-pass effect. The development of pulmonary drugs for respiratory diseases such as cystic fibrosis, lung infections, pulmon…
View article: Repetitive combined doses of bacteriophages and gentamicin protect against <i>Staphylococcus aureus</i> implant-related infections in <i>Galleria mellonella</i>
Repetitive combined doses of bacteriophages and gentamicin protect against <i>Staphylococcus aureus</i> implant-related infections in <i>Galleria mellonella</i> Open
Aims Bacteriophages infect, replicate inside bacteria, and are released from the host through lysis. Here, we evaluate the effects of repetitive doses of the Staphylococcus aureus phage 191219 and gentamicin against haematogenous and early…
View article: Development of a Galleria mellonella Infection Model to Evaluate the Efficacy of Antibiotic-Loaded Polymethyl Methacrylate (PMMA) Bone Cement
Development of a Galleria mellonella Infection Model to Evaluate the Efficacy of Antibiotic-Loaded Polymethyl Methacrylate (PMMA) Bone Cement Open
Prosthetic joint infections (PJIs) can have disastrous consequences for patient health, including removal of the device, and placement of cemented implants is often required during surgery to eradicate PJIs. In translational research, in v…
View article: Impact of mucus and biofilm on antimicrobial photodynamic therapy: Evaluation using Ruthenium(II) complexes
Impact of mucus and biofilm on antimicrobial photodynamic therapy: Evaluation using Ruthenium(II) complexes Open
The biofilm lifestyle of bacterial pathogens is a hallmark of chronic lung infections such as in cystic fibrosis (CF) patients. Bacterial adaptation to the complex conditions in CF-affected lungs and repeated antibiotherapies lead to incre…
View article: Ruthenium(II) Polypyridyl Complexes for Antimicrobial Photodynamic Therapy: Prospects for Application in Cystic Fibrosis Lung Airways
Ruthenium(II) Polypyridyl Complexes for Antimicrobial Photodynamic Therapy: Prospects for Application in Cystic Fibrosis Lung Airways Open
Antimicrobial photodynamic therapy (aPDT) depends on a variety of parameters notably related to the photosensitizers used, the pathogens to target and the environment to operate. In a previous study using a series of Ruthenium(II) polypyri…
View article: High Throughput Screening of Antimicrobial Resistance Genes in Gram-Negative Seafood Bacteria
High Throughput Screening of Antimicrobial Resistance Genes in Gram-Negative Seafood Bacteria Open
From a global view of antimicrobial resistance over different sectors, seafood and the marine environment are often considered as potential reservoirs of antimicrobial resistance genes (ARGs) and mobile genetic elements (MGEs); however, th…
View article: Antimicrobial Photodynamic Therapy: Latest Developments with a Focus on Combinatory Strategies
Antimicrobial Photodynamic Therapy: Latest Developments with a Focus on Combinatory Strategies Open
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the numerous possibilities to combine aPDT with other antimicrobial trea…