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View article: Outbreak of invasive meningococcal disease caused by a meningococcus serogroup B expressing a rare porA genosubtype (19-54, 15), Spain, March to April 2024
Outbreak of invasive meningococcal disease caused by a meningococcus serogroup B expressing a rare porA genosubtype (19-54, 15), Spain, March to April 2024 Open
In Spain during March–April 2024, an outbreak of invasive meningococcal disease (IMD) occurred in four young adults, exhibiting high case fatality with two deaths. Cases 1 and 4 were confirmed by isolation of Neisseria meningitidis from bl…
View article: Quantifying the impact of the COVID-19 pandemic on invasive bacterial diseases across 27 countries and territories: prospective surveillance by the IRIS Consortium
Quantifying the impact of the COVID-19 pandemic on invasive bacterial diseases across 27 countries and territories: prospective surveillance by the IRIS Consortium Open
Summary Background Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis are leading causes of invasive bacterial disease worldwide. The aims of this study were to measure post-COVID-19 pandemic changes in the inciden…
View article: Exploring the sequence diversity and surface expression of Factor H-Binding Protein among invasive serogroup B meningococcal strains from selected European countries
Exploring the sequence diversity and surface expression of Factor H-Binding Protein among invasive serogroup B meningococcal strains from selected European countries Open
Factor H-Binding Protein (fHbp) is a key component of meningococcal vaccines such as MenB-fHbp, licensed in the EU, UK, and other countries. Sufficient expression of fHbp on the bacterial surface is necessary for vaccine-induced antibodies…
View article: False negative result in both multiplex and monoplex PCR in a case of Neisseria meningitidis bacteremia. Diagnostic, therapeutic and epidemiological implications
False negative result in both multiplex and monoplex PCR in a case of Neisseria meningitidis bacteremia. Diagnostic, therapeutic and epidemiological implications Open
View article: Antimicrobial-resistant Neisseria gonorrhoeae in Europe in 2020 compared with in 2013 and 2018: a retrospective genomic surveillance study
Antimicrobial-resistant Neisseria gonorrhoeae in Europe in 2020 compared with in 2013 and 2018: a retrospective genomic surveillance study Open
European Centre for Disease Prevention and Control and Örebro University Hospital.
View article: Multicentric comparative study: Mortality and morbidity in C2 fractures in the elderly according to the type of treatment performed
Multicentric comparative study: Mortality and morbidity in C2 fractures in the elderly according to the type of treatment performed Open
View article: Immunogenicity of the Conjugate Meningococcal ACWY-TT Vaccine in Children and Adolescents Living with HIV
Immunogenicity of the Conjugate Meningococcal ACWY-TT Vaccine in Children and Adolescents Living with HIV Open
Background: Children and adolescents living with HIV (CALHIV) are at high risk of meningococcal infections and may present lower immune responses to vaccines. The objectives of this study were to assess the immunogenicity of the quadrivale…
View article: Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium
Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium Open
Wellcome Trust, NIHR Oxford Biomedical Research Centre, Spanish Ministry of Science and Innovation, Korea Disease Control and Prevention Agency, Torsten Söderberg Foundation, Stockholm County Council, Swedish Research Council, German Feder…
View article: Effectiveness of a Meningococcal Group B Vaccine (4CMenB) in Children
Effectiveness of a Meningococcal Group B Vaccine (4CMenB) in Children Open
Complete vaccination with 4CMenB was found to be effective in preventing invasive disease by serogroup B and non-serogroup B meningococci in children younger than 5 years of age.
View article: Coriorretinitis toxoplásmica tras inicio de tratamiento antirretroviral
Coriorretinitis toxoplásmica tras inicio de tratamiento antirretroviral Open
View article: Sustained reductions in life-threatening invasive bacterial diseases during the first two years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries participating in the IRIS Consortium
Sustained reductions in life-threatening invasive bacterial diseases during the first two years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries participating in the IRIS Consortium Open
Summary Background The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria m…
View article: Incidence of Nephrotoxicity among People Living with Human Immunodeficiency Virus on Tenofovir Treatment in a Tertiary Hospital in the Philippines
Incidence of Nephrotoxicity among People Living with Human Immunodeficiency Virus on Tenofovir Treatment in a Tertiary Hospital in the Philippines Open
Objective: We aimed to determine the incidence and risk factors of nephrotoxicity among Filipino human immunodeficiency virus (HIV) patients on tenofovir disoproxil fumarate (TDF). Methods:Retrospective cohort study; we reviewed medical re…
View article: Listeriosis outbreak caused by contaminated stuffed pork, Andalusia, Spain, July to October 2019
Listeriosis outbreak caused by contaminated stuffed pork, Andalusia, Spain, July to October 2019 Open
Between 1 July and 26 October 2019 in Andalusia, Spain, a large outbreak with 207 confirmed cases of listeriosis was identified. Confirmed cases had a median age of 44 years (range: 0–94) and 114 were women (55.1%). Most cases (n = 154) ha…
View article: Europe-wide expansion and eradication of multidrug-resistant Neisseria gonorrhoeae lineages: a genomic surveillance study
Europe-wide expansion and eradication of multidrug-resistant Neisseria gonorrhoeae lineages: a genomic surveillance study Open
View article: Pertactin-Deficient <i>Bordetella pertussis</i> with Unusual Mechanism of Pertactin Disruption, Spain, 1986–2018
Pertactin-Deficient <i>Bordetella pertussis</i> with Unusual Mechanism of Pertactin Disruption, Spain, 1986–2018 Open
Bordetella pertussis not expressing pertactin has increased in countries using acellular pertussis vaccines (ACV). The deficiency is mostly caused by pertactin gene disruption by IS481. To assess the effect of the transition from whole-cel…
View article: Impact of the Nicotinic Acetylcholine Receptor Mutation R81t on the Response of European Myzus Persicae Populations to Imidacloprid and Sulfoxaflor in Laboratory and in the Field
Impact of the Nicotinic Acetylcholine Receptor Mutation R81t on the Response of European Myzus Persicae Populations to Imidacloprid and Sulfoxaflor in Laboratory and in the Field Open
View article: Increase of invasive meningococcal serogroup W disease in Europe, 2013 to 2017
Increase of invasive meningococcal serogroup W disease in Europe, 2013 to 2017 Open
Background The total incidence of invasive meningococcal disease (IMD) in Europe has been declining in recent years; however, a rising incidence due to serogroup W (MenW), predominantly sequence type 11 (ST-11), clonal complex 11 (cc11), w…
View article: Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data
Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data Open
View article: Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide
Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide Open
gMATS can replace MATS in predicting 4CMenB strain coverage in four out of five cases, without requiring a cultivable isolate, and is open to further improvement. Both methods underestimated VE in England. Strain coverage predictions in ot…
View article: Epidemiology, molecular characterisation and antimicrobial susceptibility of<i>Neisseria gonorrhoeae</i>isolates in Madrid, Spain, in 2016
Epidemiology, molecular characterisation and antimicrobial susceptibility of<i>Neisseria gonorrhoeae</i>isolates in Madrid, Spain, in 2016 Open
With the aim to elucidate gonococcal antimicrobial resistance (AMR)–risk factors, we undertook a retrospective analysis of the molecular epidemiology and AMR of 104 Neisseria gonorrhoeae isolates from clinical samples (urethra, rectum, pha…
View article: Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide
Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide Open
Background: The Meningococcal Antigen Typing System (MATS) was developed to identify meningococcus group B strains with a high likelihood of being covered by the 4CMenB vaccine, but is limited by the requirement for viable isolates from cu…
View article: Increase of invasive meningococcal serogroup W disease in Europe, 2013 to 2017
Increase of invasive meningococcal serogroup W disease in Europe, 2013 to 2017 Open
BackgroundThe total incidence of invasive meningococcal disease (IMD) in Europe has been declining in recent years; however, a rising incidence due to serogroup W (MenW), predominantly sequence type 11 (ST-11), clonal complex 11 (cc11), wa…
View article: Meningococcal serogroups and surveillance: a systematic review and survey
Meningococcal serogroups and surveillance: a systematic review and survey Open
Due to the large geographical variations in circulating meningococcal serogroups, each country should continue to be monitored for changes in major disease-causing serogroups in order to inform vaccine and control policies. Similarly, labo…
View article: Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey
Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey Open
View article: Predicting the Susceptibility of Meningococcal Serogroup B Isolates to Bactericidal Antibodies Elicited by Bivalent rLP2086, a Novel Prophylactic Vaccine
Predicting the Susceptibility of Meningococcal Serogroup B Isolates to Bactericidal Antibodies Elicited by Bivalent rLP2086, a Novel Prophylactic Vaccine Open
Bivalent rLP2086 (Trumenba), a vaccine for prevention of Neisseria meningitidis serogroup B (NmB) disease, was licensed for use in adolescents and young adults after it was demonstrated that it elicits antibodies that initiate complement-m…
View article: 32-week premature rupture of membranes caused by oropharyngeal microbiota
32-week premature rupture of membranes caused by oropharyngeal microbiota Open
Introduction. Preterm premature rupture of membranes (PPROM) usually has a multifactorial etiology that is often unknown, although the most frequently reported cause is infection by group B Streptococcus . Therefore, the etiology of PPROM,…
View article: The epidemiology of invasive meningococcal disease in EU/EEA countries, 2004–2014
The epidemiology of invasive meningococcal disease in EU/EEA countries, 2004–2014 Open
Our findings support evidence that routine MCC vaccination was the driving force behind the decreasing SgC trend. Vaccinating against SgB in the first year of life could help reduce the burden of IMD due to this serogroup. Changing serogro…
View article: Comparison between standard and drift reducing nozzles for pesticide application in citrus: Part I. Effects on wind tunnel and field spray drift
Comparison between standard and drift reducing nozzles for pesticide application in citrus: Part I. Effects on wind tunnel and field spray drift Open
View article: Two Cases of <i>Neisseria meningitidis</i> Proctitis in HIV-Positive Men Who Have Sex with Men
Two Cases of <i>Neisseria meningitidis</i> Proctitis in HIV-Positive Men Who Have Sex with Men Open
We report 2 cases from Spain of infectious proctitis caused by Neisseria meningitidis in HIV-positive men who have sex with men. Genetic characterization of the isolates showed that they are unusual strains not found in other more frequent…
View article: Comparison between standard and drift reducing nozzles for pesticide application in citrus: Part II. Effects on canopy spray distribution, control efficacy of Aonidiella aurantii (Maskell), beneficial parasitoids and pesticide residues on fruit
Comparison between standard and drift reducing nozzles for pesticide application in citrus: Part II. Effects on canopy spray distribution, control efficacy of Aonidiella aurantii (Maskell), beneficial parasitoids and pesticide residues on fruit Open
Venturi nozzles are often recommended to reduce drift, which is one of the major pollution sources caused by the application of plant protection products on high growing crops. The coarse droplets produced by this type of nozzle could howe…